Search Results - "Ray, Soumya S." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1

Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1

by Najjar, Malek, Suebsuwong, Chalada, Ray, Soumya S., Thapa, Roshan J., Maki, Jenny L., Nogusa, Shoko, Shah, Saumil, Saleh, Danish, Gough, Peter J., Bertin, John, Yuan, Junying, Balachandran, Siddharth, Cuny, Gregory D., Degterev, Alexei
Published in Cell reports (Cambridge) (24.03.2015)

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Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates

Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates

by Duvall, Jeremy R., Thomas, Joshua D., Bukhalid, Raghida A., Catcott, Kalli C., Bentley, Keith W., Collins, Scott D., Eitas, Timothy, Jones, Brian D., Kelleher, Eugene W., Lancaster, Kelly, Protopopova, Marina, Ray, Soumya S., Ter-Ovanesyan, Elena, Xu, Ling, Yang, Liping, Zurita, Jeffrey, Damelin, Marc, Toader, Dorin, Lowinger, Timothy B.
Published in Journal of medicinal chemistry (10.08.2023)

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Structure–activity relationship study of beta-carboline derivatives as haspin kinase inhibitors

Structure–activity relationship study of beta-carboline derivatives as haspin kinase inhibitors

by Cuny, Gregory D., Ulyanova, Natalia P., Patnaik, Debasis, Liu, Ji-Feng, Lin, Xiangjie, Auerbach, Ken, Ray, Soumya S., Xian, Jun, Glicksman, Marcie A., Stein, Ross L., Higgins, Jonathan M.G.
Published in Bioorganic & medicinal chemistry letters (01.03.2012)

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Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH

Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH

by Kirubakaran, Sivapriya, Gorla, Suresh Kumar, Sharling, Lisa, Zhang, Minjia, Liu, Xiaoping, Ray, Soumya S., MacPherson, Iain S., Striepen, Boris, Hedstrom, Lizbeth, Cuny, Gregory D.
Published in Bioorganic & medicinal chemistry letters (01.03.2012)

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Structural Basis for Conformational Plasticity of the Parkinson's Disease-Associated Ubiquitin Hydrolase UCH-L1

Structural Basis for Conformational Plasticity of the Parkinson's Disease-Associated Ubiquitin Hydrolase UCH-L1

by Das, Chittaranjan, Hoang, Quyen Q., Kreinbring, Cheryl A., Luchansky, Sarah J., Meray, Robin K., Ray, Soumya S., Lansbury, Peter T., Ringe, Dagmar, Petsko, Gregory A.
Published in Proceedings of the National Academy of Sciences - PNAS (21.03.2006)

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Small-Molecule-Mediated Stabilization of Familial Amyotrophic Lateral Sclerosis-Linked Superoxide Dismutase Mutants against Unfolding and Aggregation

Small-Molecule-Mediated Stabilization of Familial Amyotrophic Lateral Sclerosis-Linked Superoxide Dismutase Mutants against Unfolding and Aggregation

by Ray, Soumya S., Nowak, Richard J., Brown, Robert H., Lansbury, Peter T., Petsko, Gregory A.
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2005)

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An Intersubunit Disulfide Bond Prevents in Vitro Aggregation of a Superoxide Dismutase-1 Mutant Linked to Familial Amytrophic Lateral Sclerosis

An Intersubunit Disulfide Bond Prevents in Vitro Aggregation of a Superoxide Dismutase-1 Mutant Linked to Familial Amytrophic Lateral Sclerosis

by Ray, Soumya S, Nowak, Richard J, Strokovich, Konstantin, Brown, Robert H, Walz, Thomas, Lansbury, Peter T
Published in Biochemistry (Easton) (04.05.2004)

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Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1

Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1

by Maki, Jenny L., Smith, Elizabeth E., Teng, Xin, Ray, Soumya S., Cuny, Gregory D., Degterev, Alexei
Published in Analytical biochemistry (15.08.2012)

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Are Deep Learning Structural Models Sufficiently Accurate for Free-Energy Calculations? Application of FEP+ to AlphaFold2-Predicted Structures

Are Deep Learning Structural Models Sufficiently Accurate for Free-Energy Calculations? Application of FEP+ to AlphaFold2-Predicted Structures

by Beuming, Thijs, Martín, Helena, Díaz-Rovira, Anna M., Díaz, Lucía, Guallar, Victor, Ray, Soumya S.
Published in Journal of chemical information and modeling (26.09.2022)

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Are Deep Learning Structural Models Sufficiently Accurate for Virtual Screening? Application of Docking Algorithms to AlphaFold2 Predicted Structures

Are Deep Learning Structural Models Sufficiently Accurate for Virtual Screening? Application of Docking Algorithms to AlphaFold2 Predicted Structures

by Díaz-Rovira, Anna M., Martín, Helena, Beuming, Thijs, Díaz, Lucía, Guallar, Victor, Ray, Soumya S.
Published in Journal of chemical information and modeling (27.03.2023)

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Destabilization of DJ-1 by Familial Substitution and Oxidative Modifications: Implications for Parkinson's Disease

Destabilization of DJ-1 by Familial Substitution and Oxidative Modifications: Implications for Parkinson's Disease

by Hulleman, John D, Mirzaei, Hamid, Guigard, Emmanuel, Taylor, Kellie L, Ray, Soumya S, Kay, Cyril M, Regnier, Fred E, Rochet, Jean-Christophe
Published in Biochemistry (Easton) (15.05.2007)

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Targeted Degradation of the Oncogenic Phosphatase SHP2

Targeted Degradation of the Oncogenic Phosphatase SHP2

by Vemulapalli, Vidyasiri, Donovan, Katherine A, Seegar, Tom C. M, Rogers, Julia M, Bae, Munhyung, Lumpkin, Ryan J, Cao, Ruili, Henke, Matthew T, Ray, Soumya S, Fischer, Eric S, Cuny, Gregory D, Blacklow, Stephen C
Published in Biochemistry (Easton) (31.08.2021)

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Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors

Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors

by Caputo, Samantha, Di Martino, Simona, Cilibrasi, Vincenzo, Tardia, Piero, Mazzonna, Marco, Russo, Debora, Penna, Ilaria, Summa, Maria, Bertozzi, Sine Mandrup, Realini, Natalia, Margaroli, Natasha, Migliore, Marco, Ottonello, Giuliana, Liu, Min, Lansbury, Peter, Armirotti, Andrea, Bertorelli, Rosalia, Ray, Soumya S, Skerlj, Renato, Scarpelli, Rita
Published in Journal of medicinal chemistry (24.12.2020)

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Type II Kinase Inhibitors Show an Unexpected Inhibition Mode against Parkinson’s Disease-Linked LRRK2 Mutant G2019S

Type II Kinase Inhibitors Show an Unexpected Inhibition Mode against Parkinson’s Disease-Linked LRRK2 Mutant G2019S

by Liu, Min, Bender, Samantha A, Cuny, Gregory D, Sherman, Woody, Glicksman, Marcie, Ray, Soumya S
Published in Biochemistry (Easton) (12.03.2013)

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A Possible Therapeutic Target for Lou Gehrig's Disease

A Possible Therapeutic Target for Lou Gehrig's Disease

by Ray, Soumya S., Lansbury, Peter T.
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2004)

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Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors

Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors

by Suebsuwong, Chalada, Pinkas, Daniel M., Ray, Soumya S., Bufton, Joshua C., Dai, Bing, Bullock, Alex N., Degterev, Alexei, Cuny, Gregory D.
Published in Bioorganic & medicinal chemistry letters (15.02.2018)

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Discovery of LRRK2 inhibitors using sequential in silico joint pharmacophore space (JPS) and ensemble docking

Discovery of LRRK2 inhibitors using sequential in silico joint pharmacophore space (JPS) and ensemble docking

by Lang, Christian A., Ray, Soumya S., Liu, Min, Singh, Ambuj K., Cuny, Gregory D.
Published in Bioorganic & medicinal chemistry letters (01.07.2015)

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Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors: a patent and scientific literature review (2002-2016)

Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors: a patent and scientific literature review (2002-2016)

by Cuny, Gregory D, Suebsuwong, Chalada, Ray, Soumya S
Published in Expert opinion on therapeutic patents (03.06.2017)

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Engineered Disulfide Bonds Restore Chaperone-like Function of DJ-1 Mutants Linked to Familial Parkinson’s Disease

Engineered Disulfide Bonds Restore Chaperone-like Function of DJ-1 Mutants Linked to Familial Parkinson’s Disease

by Logan, Todd, Clark, Lindsay, Ray, Soumya S
Published in Biochemistry (Easton) (13.07.2010)

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Improving Binding Specificity of Pharmacological Chaperones That Target Mutant Superoxide Dismutase-1 Linked to Familial Amyotrophic Lateral Sclerosis Using Computational Methods

Improving Binding Specificity of Pharmacological Chaperones That Target Mutant Superoxide Dismutase-1 Linked to Familial Amyotrophic Lateral Sclerosis Using Computational Methods

by Nowak, Richard J, Cuny, Gregory D, Choi, Sungwoon, Lansbury, Peter T, Ray, Soumya S
Published in Journal of medicinal chemistry (08.04.2010)

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