Differences in expression and function of LEF1 isoforms in normal versus leukemic hematopoiesis
Feder, Kristin, Edmaier-Schröger, Katrin, Rawat, Vijay P S, Kirsten, Nicole, Metzeler, Klaus, Kraus, Johann M, Döhner, Konstanze, Döhner, Hartmut, Kestler, Hans A, Feuring-Buske, Michaela, Buske, Christian
Published in Leukemia (01.04.2020)
Published in Leukemia (01.04.2020)
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vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia
Rawat, Vijay P.S, Arseni, Natalia, Ahmed, Farid, Mulaw, Medhanie A, Thoene, Silvia, Heilmeier, Bernhard, Sadlon, Tim, D'Andrea, Richard J, Hiddemann, Wolfgang, Bohlander, Stefan K, Buske, Christian, Feuring-Buske, Michaela
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.2010)
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Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström's Macroglobulinemia
Kaiser, Lisa Marie, Harms, Mirja, Sauter, Daniel, Rawat, Vijay P S, Glitscher, Mirco, Hildt, Eberhard, Tews, Daniel, Hunter, Zachary, Münch, Jan, Buske, Christian
Published in Cancers (16.02.2021)
Published in Cancers (16.02.2021)
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The microRNA miR-196b acts as a tumor suppressor in Cdx2-driven acute myeloid leukemia
Rawat, Vijay P S, Götze, Maria, Rasalkar, Avinash, Vegi, Naidu M, Ihme, Susann, Thoene, Silvia, Pastore, Alessandro, Bararia, Deepak, Döhner, Hartmut, Döhner, Konstanze, Feuring-Buske, Michaela, Quintanilla-Fend, Leticia, Buske, Christian
Published in Haematologica (Roma) (01.06.2020)
Published in Haematologica (Roma) (01.06.2020)
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High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia
Metzeler, Klaus H., Heilmeier, Bernhard, Edmaier, Katrin E., Rawat, Vijay P.S., Dufour, Annika, Döhner, Konstanze, Feuring-Buske, Michaela, Braess, Jan, Spiekermann, Karsten, Büchner, Thomas, Sauerland, Maria C., Döhner, Hartmut, Hiddemann, Wolfgang, Bohlander, Stefan K., Schlenk, Richard F., Bullinger, Lars, Buske, Christian
Published in Blood (06.09.2012)
Published in Blood (06.09.2012)
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Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia
Rawat, Vijay P.S., Thoene, Silvia, Naidu, Vegi M., Arseni, Natalia, Heilmeier, Bernhard, Metzeler, Klaus, Petropoulos, Konstantin, Deshpande, Aniruddha, Quintanilla-Martinez, Leticia, Bohlander, Stefan K., Spiekermann, Karsten, Hiddemann, Wolfgang, Feuring-Buske, Michaela, Buske, Christian
Published in Blood (01.01.2008)
Published in Blood (01.01.2008)
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MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML
Vegi, Naidu M., Klappacher, Josef, Oswald, Franz, Mulaw, Medhanie A., Mandoli, Amit, Thiel, Verena N., Bamezai, Shiva, Feder, Kristin, Martens, Joost H.A., Rawat, Vijay P.S., Mandal, Tamoghna, Quintanilla-Martinez, Leticia, Spiekermann, Karsten, Hiddemann, Wolfgang, Döhner, Konstanze, Döhner, Hartmut, Stunnenberg, Hendrik G., Feuring-Buske, Michaela, Buske, Christian
Published in Cell reports (Cambridge) (12.07.2016)
Published in Cell reports (Cambridge) (12.07.2016)
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A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis
Petropoulos, Konstantin, Arseni, Natalia, Schessl, Christina, Stadler, Christiane R, Rawat, Vijay P S, Deshpande, Aniruddha J, Heilmeier, Bernhard, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Bohlander, Stefan K, Feuring-Buske, Michaela, Buske, Christian
Published in The Journal of experimental medicine (17.03.2008)
Published in The Journal of experimental medicine (17.03.2008)
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Journal Article
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia
Deshpande, Aniruddha J., Cusan, Monica, Rawat, Vijay P.S., Reuter, Hendrik, Krause, Alexandre, Pott, Christiane, Quintanilla-Martinez, Leticia, Kakadia, Purvi, Kuchenbauer, Florian, Ahmed, Farid, Delabesse, Eric, Hahn, Meinhard, Lichter, Peter, Kneba, Michael, Hiddemann, Wolfgang, Macintyre, Elizabeth, Mecucci, Cristina, Ludwig, Wolf-Dieter, Humphries, R. Keith, Bohlander, Stefan K., Feuring-Buske, Michaela, Buske, Christian
Published in Cancer cell (01.11.2006)
Published in Cancer cell (01.11.2006)
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Ectopic Expression of the Homeobox Gene Cdx2 Is the Transforming Event in a Mouse Model of t(12;13)(p13;q12) Acute Myeloid Leukemia
Vijay P. S. Rawat, Cusan, Monica, Deshpande, Aniruddha, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Humphries, R. Keith, Bohlander, Stefan K., Feuring-Buske, Michaela, Buske, Christian
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2004)
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TET3 promotes AML growth and epigenetically regulates glucose metabolism and leukemic stem cell associated pathways
Pulikkottil, Alex Jose, Bamezai, Shiva, Ammer, Tobias, Mohr, Fabian, Feder, Kristin, Vegi, Naidu M, Mandal, Tamoghna, Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Sinha, Amit, Buske, Christian, Rawat, Vijay P S
Published in Leukemia (01.02.2022)
Published in Leukemia (01.02.2022)
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Journal Article
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition
Bamezai, Shiva, Demir, Deniz, Pulikkottil, Alex Jose, Ciccarone, Fabio, Fischbein, Elena, Sinha, Amit, Borga, Chiara, Te Kronnie, Geertruy, Meyer, Lüder-Hinrich, Mohr, Fabian, Götze, Maria, Caiafa, Paola, Debatin, Klaus-Michael, Döhner, Konstanze, Döhner, Hartmut, González-Menéndez, Irene, Quintanilla-Fend, Leticia, Herold, Tobias, Jeremias, Irmela, Feuring-Buske, Michaela, Buske, Christian, Rawat, Vijay P S
Published in Leukemia (01.02.2021)
Published in Leukemia (01.02.2021)
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Concise Review: The Piwi-piRNA Axis: Pivotal Beyond Transposon Silencing
Bamezai, Shiva, Rawat, Vijay P.S., Buske, Christian
Published in Stem cells (Dayton, Ohio) (01.12.2012)
Published in Stem cells (Dayton, Ohio) (01.12.2012)
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A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML
Bamezai, Shiva, Pulikkottil, Alex Jose, Yadav, Tribhuwan, Vegi, Naidu M., Mueller, Julia, Mark, Jasmin, Mandal, Tamoghna, Feder, Kristin, Ihme, Susann, Song, Chenlin, Rosler, Reinhild, Wiese, Sebastian, Hoell, Jessica I., Kloetgen, Andreas, Karsan, Aly, Kumari, Ankita, Wojenski, Luke, Sinha, Amit U., Gonzalez-Menendez, Irene, Quintanilla-Martinez, Leticia, Donato, Elisa, Trumpp, Andreas, Kruse, Elisabeth, Hamperl, Stephan, Zou, Lee, Rawat, Vijay P. S., Buske, Christian
Published in Blood (06.07.2023)
Published in Blood (06.07.2023)
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Somatostatin receptor mediated targeting of acute myeloid leukemia by photodynamic metal complexes for light induced apoptosis
Vegi, Naidu M, Chakrabortty, Sabyasachi, Zegota, Maksymilian M, Kuan, Seah Ling, Stumper, Anne, Rawat, Vijay P S, Sieste, Stefanie, Buske, Christian, Rau, Sven, Weil, Tanja, Feuring-Buske, Michaela
Published in Scientific reports (15.01.2020)
Published in Scientific reports (15.01.2020)
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Journal Article
TET Genes: new players in DNA demethylation and important determinants for stemness
Mohr, Fabian, Döhner, Konstanze, Buske, Christian, Rawat, Vijay P.S
Published in Experimental hematology (01.03.2011)
Published in Experimental hematology (01.03.2011)
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Npm1 haploinsufficiency in collaboration with MEIS1 is sufficient to induce AML in mice
Muranyi, Andrew, Ammer, Tobias, Kechter, Anna, Rawat, Vijay P. S., Sinha, Amit, Gonzalez-Menendez, Irene, Quintanilla-Martinez, Leticia, Azoitei, Anca, Günes, Cagatay, Mupo, Annalisa, Vassiliou, George, Bamezai, Shiva, Buske, Christian
Published in Blood advances (14.02.2023)
Published in Blood advances (14.02.2023)
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Journal Article
VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice
Gentner, Eva, Vegi, Naidu M, Mulaw, Medhanie A, Mandal, Tamoghna, Bamezai, Shiva, Claus, Rainer, Tasdogan, Alpaslan, Quintanilla-Martinez, Leticia, Grunenberg, Alexander, Döhner, Konstanze, Döhner, Hartmut, Bullinger, Lars, Haferlach, Torsten, Buske, Christian, Rawat, Vijay P S, Feuring-Buske, Michaela
Published in Oncotarget (27.12.2016)
Published in Oncotarget (27.12.2016)
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Journal Article
The ParaHox gene Cdx4 induces acute erythroid leukemia in mice
Thoene, Silvia, Mandal, Tamoghna, Vegi, Naidu M., Quintanilla-Martinez, Leticia, Rösler, Reinhild, Wiese, Sebastian, Metzeler, Klaus H., Herold, Tobias, Haferlach, Torsten, Döhner, Konstanze, Döhner, Hartmut, Schwarzmüller, Luisa, Klingmüller, Ursula, Buske, Christian, Rawat, Vijay P.S., Feuring-Buske, Michaela
Published in Blood advances (26.11.2019)
Published in Blood advances (26.11.2019)
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