Discovery, Synthesis, and Characterization of an Orally Bioavailable, Brain Penetrant Inhibitor of Mixed Lineage Kinase 3
Goodfellow, Val S, Loweth, Colin J, Ravula, Satheesh B, Wiemann, Torsten, Nguyen, Thong, Xu, Yang, Todd, Daniel E, Sheppard, David, Pollack, Scott, Polesskaya, Oksana, Marker, Daniel F, Dewhurst, Stephen, Gelbard, Harris A
Published in Journal of medicinal chemistry (24.10.2013)
Published in Journal of medicinal chemistry (24.10.2013)
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Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state
Woller, Sarah A, Ravula, Satheesh B, Tucci, Fabio C, Beaton, Graham, Corr, Maripat, Rivkah Isseroff, R, Soulika, Athena M, Chigbrow, Marianne, Eddinger, Kelly A, Yaksh, Tony L
Published in Brain, behavior, and immunity (01.08.2016)
Published in Brain, behavior, and immunity (01.08.2016)
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Lysophosphatidic acid receptor 1 antagonist (EPGN2154) causes regression of NASH in preclinical NASH models
Bhattacharjee, Jashdeep, Beaton, Graham, Ravula, Satheesh B, Lee, Suk Joong, Bacon, Kevin B, Jenkinson, Celia P, Warren, Mikako, Tucci, Fabio C, Kohli, Rohit
Published in Hepatology communications (01.12.2023)
Published in Hepatology communications (01.12.2023)
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90 Efficacy of a Novel Small Molecule RORgt Inverse Agonist in Mouse DSS and TNBS Models of Inflammatory Bowel Disease
Fitzpatrick, Leo R, Zapf, Jim, Flood, Elizabeth M, Ravula, Satheesh B, Lingardo, Laura K, Small, Jeff, Tucci, Fabio, Buhr, Chris A, Alton, Gordon
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2015)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2015)
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피리미딘 및 피리딘 아민 화합물 및 질병의 치료에서 이의 용도
LEE SUK JOONG, RAVULA SATHEESH B, SHAH CHANDRAVADAN R, TUCCI FABIO, BEATON GRAHAM
Year of Publication 06.02.2024
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Year of Publication 06.02.2024
Patent
질환의 치료에 유용한 헤테로환식 화합물
LEE SUK JOONG, RAVULA SATHEESH B, TUCCI FABIO C, SHAH CHANDRAVADAN R, BEATON GRAHAM
Year of Publication 27.01.2021
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Year of Publication 27.01.2021
Patent
HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE
RAVULA SATHEESH B, TUCCI FABIO C, SHAH CHANDRAVADAN R, LIU HIEP, BEATON GRAHAM
Year of Publication 23.11.2015
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Year of Publication 23.11.2015
Patent
OLIG2 활성의 억제
RAVULA SATHEESH B, RUIZ FRANCISCO XAVIER III, CAMPOS BISMARCK, TUCCI FABIO C, MCHARDY STANTON F, LOPEZ AMBROSIO JR, WANG HUA YU LEO, BEATON GRAHAM
Year of Publication 27.11.2017
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Year of Publication 27.11.2017
Patent
Discovery, Synthesis, and Characterization of an Orally Bioavailable, Brain Penetrant Inhibitor of Mixed Lineage Kinase
Goodfellow, Val S., Loweth, Colin J., Ravula, Satheesh B., Wiemann, Torsten, Thong Nguyen, Xu, Yang, Todd, Daniel E., Sheppard, David, Pollack, Scott, Polesskaya, Oksana, Marker, Daniel F., Dewhurst, Stephen, Gelbard, Harris A.
Published in Journal of medicinal chemistry (24.10.2013)
Published in Journal of medicinal chemistry (24.10.2013)
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Journal Article
Heterocyclic compounds useful in the treatment of disease
TUCCI, Fabio C, SHAH, Chandravadan R, BEATON, Graham, LEE, Suk Joong, RAVULA, Satheesh B
Year of Publication 01.08.2024
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Year of Publication 01.08.2024
Patent
PYRIMIDINE AND PYRIDINE AMINE COMPOUNDS AND USAGE THEREOF IN DISEASE TREATMENT
TUCCI, Fabio, SHAH, Chandravadan, R, RAVULA, Satheesh, B, BEATON, Graham, LEE, Suk, Joong
Year of Publication 10.04.2024
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Year of Publication 10.04.2024
Patent
Pyrimidine and pyridine amine compounds and usage thereof in disease treatment
TUCCI Fabio, RAVULA Satheesh B, SHAH Chandravadan R, BEATON Graham, LEE Suk Joong
Year of Publication 01.01.2024
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Year of Publication 01.01.2024
Patent
HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE
TUCCI, Fabio C, SHAH, Chandravadan R, BEATON, Graham, LEE, Suk Joong, RAVULA, Satheesh B
Year of Publication 14.09.2023
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Year of Publication 14.09.2023
Patent
HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE
SHAH, CHANDRAVADAN R, LUU, HIEP, TUCCI, FABIO C, BEATON, GRAHAM, RAVULA, SATHEESH B
Year of Publication 14.03.2023
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Year of Publication 14.03.2023
Patent
PYRIMIDINE AND PYRIDINE AMINE COMPOUNDS AND USAGE THEREOF IN DISEASE TREATMENT
SHAH, CHANDRAVADAN R, LEE, SUK JOONG, BEATON, GRAHAM, RAVULA, SATHEESH B, TUCCI, FABIO
Year of Publication 08.12.2022
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Year of Publication 08.12.2022
Patent
Heterocyclic compounds useful in the treatment of disease
Ravula, Satheesh B, Shah, Chandravadan R, Luu, Hiep, Beaton, Graham, Tucci, Fabio C
Year of Publication 30.08.2022
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Year of Publication 30.08.2022
Patent
HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE
TUCCI, Fabio C, SHAH, Chandravadan R, BEATON, Graham, LEE, Suk Joong, RAVULA, Satheesh B
Year of Publication 23.03.2022
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Year of Publication 23.03.2022
Patent
INHIBITION OF OLIG2 ACTIVITY
TUCCI, Fabio C, CAMPOS, Bismarck, WANG, Hua-Yu Leo, McHARDY, Stanton F, BEATON, Graham, RAVULA, Satheesh B, LOPEZ, Ambrosio, RUIZ, Francisco Xavier
Year of Publication 31.08.2023
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Year of Publication 31.08.2023
Patent