AIM2 in health and disease: Inflammasome and beyond
Kumari, Puja, Russo, Ashley J., Shivcharan, Sonia, Rathinam, Vijay A.
Published in Immunological reviews (01.09.2020)
Published in Immunological reviews (01.09.2020)
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Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
Jin, Tengchuan, Perry, Andrew, Jiang, Jiansheng, Smith, Patrick, Curry, James A., Unterholzner, Leonie, Jiang, Zhaozhao, Horvath, Gabor, Rathinam, Vijay A., Johnstone, Ricky W., Hornung, Veit, Latz, Eicke, Bowie, Andrew G., Fitzgerald, Katherine A., Xiao, T. Sam
Published in Immunity (Cambridge, Mass.) (20.04.2012)
Published in Immunity (Cambridge, Mass.) (20.04.2012)
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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis
Banerjee, Ishita, Behl, Bharat, Mendonca, Morena, Shrivastava, Gaurav, Russo, Ashley J., Menoret, Antoine, Ghosh, Arundhati, Vella, Anthony T., Vanaja, Sivapriya Kailasan, Sarkar, Saumendra N., Fitzgerald, Katherine A., Rathinam, Vijay A.K.
Published in Immunity (Cambridge, Mass.) (18.09.2018)
Published in Immunity (Cambridge, Mass.) (18.09.2018)
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Journal Article
A TLR4-independent critical role for CD14 in intracellular LPS sensing
Vasudevan, Swathy O., Russo, Ashley J., Kumari, Puja, Vanaja, Sivapriya Kailasan, Rathinam, Vijay A.
Published in Cell reports (Cambridge) (03.05.2022)
Published in Cell reports (Cambridge) (03.05.2022)
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Journal Article
Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production
Ghosh, Arundhati, Shao, Lulu, Sampath, Padmavathi, Zhao, Baoyu, Patel, Nidhi V., Zhu, Jianzhong, Behl, Bharat, Parise, Robert A., Beumer, Jan H., O’Sullivan, Roderick J., DeLuca, Neal A., Thorne, Stephen H., Rathinam, Vijay A.K., Li, Pingwei, Sarkar, Saumendra N.
Published in Immunity (Cambridge, Mass.) (15.01.2019)
Published in Immunity (Cambridge, Mass.) (15.01.2019)
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Journal Article
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
Rathinam, Vijay A K, Jiang, Zhaozhao, Vanaja, Sivapriya Kailasan, Vogel, Stefanie N, Waggoner, Lisa, Waggoner, Stephen N, Sharma, Shruti, Monks, Brian G, Ganesan, Sandhya, Cole, Leah E, Hornung, Veit, Fitzgerald, Katherine A, Latz, Eicke, Szomolanyi-Tsuda, Eva
Published in Nature immunology (01.05.2010)
Published in Nature immunology (01.05.2010)
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Journal Article
Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome
Vanaja, Sivapriya Kailasan, Rathinam, Vijay A. K., Atianand, Maninjay K., Kalantari, Parisa, Skehan, Brian, Fitzgerald, Katherine A., Leong, John M.
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
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A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3
Ta, Atri, Ricci-Azevedo, Rafael, Vasudevan, Swathy O, Wright, Skylar S, Kumari, Puja, Havira, Morena S, Surendran Nair, Meera, Rathinam, Vijay A, Vanaja, Sivapriya Kailasan
Published in Nature communications (11.04.2023)
Published in Nature communications (11.04.2023)
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Journal Article
Anti-diabetic and hypolipidemic effects of Cinnamon cassia bark extracts: an in vitro, in vivo, and in silico approach
Vijayakumar, K., Prasanna, B., Rengarajan, R. L., Rathinam, A., Velayuthaprabhu, S., Vijaya Anand, A.
Published in Archives of physiology and biochemistry (04.03.2023)
Published in Archives of physiology and biochemistry (04.03.2023)
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Journal Article
CD169+ macrophage intrinsic IL-10 production regulates immune homeostasis during sepsis
Yeung, Stephen T., Ovando, Luis J., Russo, Ashley J., Rathinam, Vijay A., Khanna, Kamal M.
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Journal Article
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
Sokolovska, Anna, Becker, Christine E, Ip, W K Eddie, Rathinam, Vijay A K, Brudner, Matthew, Paquette, Nicholas, Tanne, Antoine, Vanaja, Sivapriya K, Moore, Kathryn J, Fitzgerald, Katherine A, Lacy-Hulbert, Adam, Stuart, Lynda M
Published in Nature immunology (01.06.2013)
Published in Nature immunology (01.06.2013)
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Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid
Conlon, Joseph, Burdette, Dara L, Sharma, Shruti, Bhat, Numana, Thompson, Mikayla, Jiang, Zhaozhao, Rathinam, Vijay A K, Monks, Brian, Jin, Tengchuan, Xiao, T Sam, Vogel, Stefanie N, Vance, Russell E, Fitzgerald, Katherine A
Published in The Journal of immunology (1950) (15.05.2013)
Published in The Journal of immunology (1950) (15.05.2013)
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