Rociletinib in EGFR-Mutated Non–Small-Cell Lung Cancer
Sequist, Lecia V, Soria, Jean-Charles, Goldman, Jonathan W, Wakelee, Heather A, Gadgeel, Shirish M, Varga, Andrea, Papadimitrakopoulou, Vassiliki, Solomon, Benjamin J, Oxnard, Geoffrey R, Dziadziuszko, Rafal, Aisner, Dara L, Doebele, Robert C, Galasso, Cathy, Garon, Edward B, Heist, Rebecca S, Logan, Jennifer, Neal, Joel W, Mendenhall, Melody A, Nichols, Suzanne, Piotrowska, Zofia, Wozniak, Antoinette J, Raponi, Mitch, Karlovich, Chris A, Jaw-Tsai, Sarah, Isaacson, Jeffrey, Despain, Darrin, Matheny, Shannon L, Rolfe, Lindsey, Allen, Andrew R, Camidge, D. Ross
Published in The New England journal of medicine (30.04.2015)
Published in The New England journal of medicine (30.04.2015)
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Journal Article
Exosome-Based Detection of EGFR T790M in Plasma from Non-Small Cell Lung Cancer Patients
Castellanos-Rizaldos, Elena, Grimm, Dominik G, Tadigotla, Vasisht, Hurley, James, Healy, John, Neal, Patricia L, Sher, Mia, Venkatesan, Raajdeep, Karlovich, Chris, Raponi, Mitch, Krug, Anne, Noerholm, Mikkel, Tannous, Jihane, Tannous, Bakhos A, Raez, Luis E, Skog, Johan K
Published in Clinical cancer research (15.06.2018)
Published in Clinical cancer research (15.06.2018)
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Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial
Swisher, Elizabeth M, Dr Prof, Lin, Kevin K, PhD, Oza, Amit M, Prof, Scott, Clare L, PhD, Giordano, Heidi, MA, Sun, James, PhD, Konecny, Gottfried E, MD, Coleman, Robert L, Prof, Tinker, Anna V, MD, O'Malley, David M, MD, Kristeleit, Rebecca S, MD, Ma, Ling, MD, Bell-McGuinn, Katherine M, MD, Brenton, James D, Prof, Cragun, Janiel M, MD, Oaknin, Ana, MD, Ray-Coquard, Isabelle, Prof, Harrell, Maria I, PhD, Mann, Elaina, MS, Kaufmann, Scott H, Prof, Floquet, Anne, MD, Leary, Alexandra, MD, Harding, Thomas C, PhD, Goble, Sandra, MS, Maloney, Lara, BA, Isaacson, Jeff, PhD, Allen, Andrew R, MD, Rolfe, Lindsey, MBChB, Yelensky, Roman, PhD, Raponi, Mitch, PhD, McNeish, Iain A, Prof
Published in The lancet oncology (2017)
Published in The lancet oncology (2017)
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Journal Article
MicroRNA Classifiers for Predicting Prognosis of Squamous Cell Lung Cancer
RAPONI, Mitch, DOSSEY, Lesley, JATKOE, Tim, XIAOYING WU, GUOAN CHEN, HONGTAO FAN, BEER, David G
Published in Cancer research (Chicago, Ill.) (15.07.2009)
Published in Cancer research (Chicago, Ill.) (15.07.2009)
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Journal Article
A Highly Sensitive and Quantitative Test Platform for Detection of NSCLC EGFR Mutations in Urine and Plasma
Reckamp, Karen L., Melnikova, Vladislava O., Karlovich, Chris, Sequist, Lecia V., Camidge, D. Ross, Wakelee, Heather, Perol, Maurice, Oxnard, Geoffrey R., Kosco, Karena, Croucher, Peter, Samuelsz, Errin, Vibat, Cecile Rose, Guerrero, Shiloh, Geis, Jennifer, Berz, David, Mann, Elaina, Matheny, Shannon, Rolfe, Lindsey, Raponi, Mitch, Erlander, Mark G., Gadgeel, Shirish
Published in Journal of thoracic oncology (01.10.2016)
Published in Journal of thoracic oncology (01.10.2016)
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Journal Article
Assessment of EGFR Mutation Status in Matched Plasma and Tumor Tissue of NSCLC Patients from a Phase I Study of Rociletinib (CO-1686)
Karlovich, Chris, Goldman, Jonathan W, Sun, Jong-Mu, Mann, Elaina, Sequist, Lecia V, Konopa, Krzysztof, Wen, Wei, Angenendt, Philipp, Horn, Leora, Spigel, David, Soria, Jean-Charles, Solomon, Benjamin, Camidge, D Ross, Gadgeel, Shirish, Paweletz, Cloud, Wu, Lin, Chien, Sean, O'Donnell, Patrick, Matheny, Shannon, Despain, Darrin, Rolfe, Lindsey, Raponi, Mitch, Allen, Andrew R, Park, Keunchil, Wakelee, Heather
Published in Clinical cancer research (15.05.2016)
Published in Clinical cancer research (15.05.2016)
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Journal Article
Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer
Arndt, Greg M, Dossey, Lesley, Cullen, Lara M, Lai, Angela, Druker, Riki, Eisbacher, Michael, Zhang, Chunyan, Tran, Nham, Fan, Hongtao, Retzlaff, Kathy, Bittner, Anton, Raponi, Mitch
Published in BMC cancer (20.10.2009)
Published in BMC cancer (20.10.2009)
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Randomized, Multicenter, Phase II Study of CO-101 Versus Gemcitabine in Patients With Metastatic Pancreatic Ductal Adenocarcinoma: Including a Prospective Evaluation of the Role of hENT1 in Gemcitabine or CO-101 Sensitivity
POPLIN, Elizabeth, WASAN, Harpreet, ORMANNS, Steffen, HEINEMANN, Volker, BASSI, Claudio, EVANS, T. R. Jeffrey, ANDERSSON, Roland, HEJIN HAHN, PICOZZI, Vince, DICKER, Adam, MANN, Elaina, VOONG, Cynthia, ROLFE, Lindsey, KAUR, Paramjit, ISAACSON, Jeff, ALLEN, Andrew, RAPONI, Mitch, IKDAHL, Tone, BONDARENKO, Ihor, DAVIDENKO, Irina, BONDAR, Volodymyr, GARIN, August, BOECK, Stefan
Published in Journal of clinical oncology (10.12.2013)
Published in Journal of clinical oncology (10.12.2013)
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Journal Article
Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung
RAPONI, Mitch, YI ZHANG, BEER, David G, YU, Jack, GUOAN CHEN, LEE, Grace, TAYLOR, Jeremy M. G, MACDONALD, James, THOMAS, Dafydd, MOSKALUK, Christopher, YIXIN WANG
Published in Cancer research (Chicago, Ill.) (01.08.2006)
Published in Cancer research (Chicago, Ill.) (01.08.2006)
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Journal Article
A Quantitative Chemotherapy Genetic Interaction Map Reveals Factors Associated with PARP Inhibitor Resistance
Hu, Hsien-Ming, Zhao, Xin, Kaushik, Swati, Robillard, Lilliane, Barthelet, Antoine, Lin, Kevin K., Shah, Khyati N., Simmons, Andy D., Raponi, Mitch, Harding, Thomas C., Bandyopadhyay, Sourav
Published in Cell reports (Cambridge) (17.04.2018)
Published in Cell reports (Cambridge) (17.04.2018)
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Journal Article
A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia
Raponi, Mitch, Lancet, Jeffrey E., Fan, Hongtao, Dossey, Lesley, Lee, Grace, Gojo, Ivana, Feldman, Eric J., Gotlib, Jason, Morris, Lawrence E., Greenberg, Peter L., Wright, John J., Harousseau, Jean-Luc, Löwenberg, Bob, Stone, Richard M., De Porre, Peter, Wang, Yixin, Karp, Judith E.
Published in Blood (01.03.2008)
Published in Blood (01.03.2008)
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Journal Article
Identification of Molecular Predictors of Response in a Study of Tipifarnib Treatment in Relapsed and Refractory Acute Myelogenous Leukemia
RAPONI, Mitch, HAROUSSEAU, Jean-Luc, LANCET, Jeffrey E, LÖWENBERG, Bob, STONE, Richard, YI ZHANG, RACKOFF, Wayne, YIXIN WANG, ATKINS, David
Published in Clinical cancer research (01.04.2007)
Published in Clinical cancer research (01.04.2007)
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Journal Article
Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia
Raponi, Mitch, Belly, Robert T, Karp, Judith E, Lancet, Jeffrey E, Atkins, David, Wang, Yixin
Published in BMC cancer (25.08.2004)
Published in BMC cancer (25.08.2004)
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Journal Article
Results of ARIEL2: A Phase 2 trial to prospectively identify ovarian cancer patients likely to respond to rucaparib using tumor genetic analysis
McNeish, Iain A., Oza, Amit M., Coleman, Robert L., Scott, Clare L., Konecny, Gottfried E., Tinker, Anna, O'Malley, David M., Brenton, James, Kristeleit, Rebecca Sophie, Bell-McGuinn, Katherine, Oaknin, Ana, Leary, Alexandra, Lin, Kevin, Raponi, Mitch, Giordano, Heidi, Goble, Sandra, Rolfe, Lindsey, Yelensky, Roman, Allen, Andrew R., Swisher, Elizabeth M.
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2
Oza, Amit M., Tinker, Anna V., Oaknin, Ana, Shapira-Frommer, Ronnie, McNeish, Iain A., Swisher, Elizabeth M., Ray-Coquard, Isabelle, Bell-McGuinn, Katherine, Coleman, Robert L., O'Malley, David M., Leary, Alexandra, Chen, Lee-may, Provencher, Diane, Ma, Ling, Brenton, James D., Konecny, Gottfried E., Castro, Cesar M., Giordano, Heidi, Maloney, Lara, Goble, Sandra, Lin, Kevin K., Sun, James, Raponi, Mitch, Rolfe, Lindsey, Kristeleit, Rebecca S.
Published in Gynecologic oncology (01.11.2017)
Published in Gynecologic oncology (01.11.2017)
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Journal Article
Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma
Kondrashova, Olga, Nguyen, Minh, Shield-Artin, Kristy, Tinker, Anna V, Teng, Nelson N H, Harrell, Maria I, Kuiper, Michael J, Ho, Gwo-Yaw, Barker, Holly, Jasin, Maria, Prakash, Rohit, Kass, Elizabeth M, Sullivan, Meghan R, Brunette, Gregory J, Bernstein, Kara A, Coleman, Robert L, Floquet, Anne, Friedlander, Michael, Kichenadasse, Ganessan, O'Malley, David M, Oza, Amit, Sun, James, Robillard, Liliane, Maloney, Lara, Bowtell, David, Giordano, Heidi, Wakefield, Matthew J, Kaufmann, Scott H, Simmons, Andrew D, Harding, Thomas C, Raponi, Mitch, McNeish, Iain A, Swisher, Elizabeth M, Lin, Kevin K, Scott, Clare L
Published in Cancer discovery (01.09.2017)
Published in Cancer discovery (01.09.2017)
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Journal Article
Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC
Walter, Annette O, Sjin, Robert Tjin Tham, Haringsma, Henry J, Ohashi, Kadoaki, Sun, Jing, Lee, Kwangho, Dubrovskiy, Aleksandr, Labenski, Matthew, Zhu, Zhendong, Wang, Zhigang, Sheets, Michael, St Martin, Thia, Karp, Russell, van Kalken, Dan, Chaturvedi, Prasoon, Niu, Deqiang, Nacht, Mariana, Petter, Russell C, Westlin, William, Lin, Kevin, Jaw-Tsai, Sarah, Raponi, Mitch, Van Dyke, Terry, Etter, Jeff, Weaver, Zoe, Pao, William, Singh, Juswinder, Simmons, Andrew D, Harding, Thomas C, Allen, Andrew
Published in Cancer discovery (01.12.2013)
Published in Cancer discovery (01.12.2013)
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Journal Article
KRAS mutations predict response to EGFR inhibitors
Raponi, Mitch, Winkler, Hans, Dracopoli, Nicholas C
Published in Current opinion in pharmacology (01.08.2008)
Published in Current opinion in pharmacology (01.08.2008)
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Journal Article
NAPRT Silencing in FH-Deficient Renal Cell Carcinoma Confers Therapeutic Vulnerabilities via NAD+ Depletion
Noronha, Katelyn J., Lucas, Karlie N., Paradkar, Sateja, Edmonds, Joseph, Friedman, Sam, Murray, Matthew A., Liu, Samantha, Sajed, Dipti P., Sachs, Chana, Spurrier, Josh, Raponi, Mitch, Liang, Jiayu, Zeng, Hao, Sundaram, Ranjini K., Shuch, Brian, Vasquez, Juan C., Bindra, Ranjit S.
Published in Molecular cancer research (31.07.2024)
Published in Molecular cancer research (31.07.2024)
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A phase III, double-blind, randomized study of pamiparib versus placebo as maintenance therapy in patients with inoperable, locally advanced, or metastatic gastric cancer (GC) that responded to platinum-based first-line chemotherapy
Ciardiello, Fortunato, Bang, Yung-Jue, Bendell, Johanna C., Cervantes, Andres, Brachmann, Rainer Karl, Zhang, Yuting, Raponi, Mitch, Farin, Heinrich, Lin, Shen
Published in Journal of clinical oncology (01.02.2019)
Published in Journal of clinical oncology (01.02.2019)
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