Clinical impact of pharmacogenetic profiling with a clinical decision support tool in polypharmacy home health patients: A prospective pilot randomized controlled trial
Elliott, Lindsay S, Henderson, John C, Neradilek, Moni B, Moyer, Nicolas A, Ashcraft, Kristine C, Thirumaran, Ranjit K
Published in PloS one (02.02.2017)
Published in PloS one (02.02.2017)
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Journal Article
Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier
Yasuda, Kazuto, Cline, Cynthia, Vogel, Peter, Onciu, Mihaela, Fatima, Soghra, Sorrentino, Brian P, Thirumaran, Ranjit K, Ekins, Sean, Urade, Yoshihiro, Fujimori, Ko, Schuetz, Erin G
Published in Drug metabolism and disposition (01.04.2013)
Published in Drug metabolism and disposition (01.04.2013)
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Journal Article
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis
Ugurel, Selma, Thirumaran, Ranjit K, Bloethner, Sandra, Gast, Andreas, Sucker, Antje, Mueller-Berghaus, Jan, Rittgen, Werner, Hemminki, Kari, Becker, Jürgen C, Kumar, Rajiv, Schadendorf, Dirk
Published in PloS one (21.02.2007)
Published in PloS one (21.02.2007)
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Journal Article
Cytochrome P-450 gene and drug interaction analysis in patients referred for pharmacogenetic testing
Hocum, Brian Thomas, White, John Raymond, Heck, Jarrod W, Thirumaran, Ranjit K, Moyer, Nicolas, Newman, Richard, Ashcraft, Kristine
Published in American journal of health-system pharmacy (15.01.2016)
Published in American journal of health-system pharmacy (15.01.2016)
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Journal Article
Metabolism of Low-Dose Inorganic Arsenic in a Central European Population: Influence of Sex and Genetic Polymorphisms
Anna-Lena Lindberg, Kumar, Rajiv, Walter Goessler, Ranjit Thirumaran, Eugen Gurzau, Kvetoslava Koppova, Rudnai, Peter, Giovanni Leonardi, Fletcher, Tony, Vahter, Marie
Published in Environmental health perspectives (01.07.2007)
Published in Environmental health perspectives (01.07.2007)
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Journal Article
In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
Yasuda, Kazuto, Cline, Cynthia, Lin, Yvonne S, Scheib, Rachel, Ganguly, Samit, Thirumaran, Ranjit K, Chaudhry, Amarjit, Kim, Richard B, Schuetz, Erin G
Published in Drug metabolism and disposition (01.11.2015)
Published in Drug metabolism and disposition (01.11.2015)
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Journal Article
Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation
Thirumaran, Ranjit K., Lamba, Jatinder K., Kim, Richard B., Urquhart, Brad L., Gregor, Jamie C., Chande, Nilesh, Fan, Yiping, Qi, An, Cheng, Cheng, Thummel, Kenneth E., Hall, Stephen D., Schuetz, Erin G.
Published in Biochemical pharmacology (01.07.2012)
Published in Biochemical pharmacology (01.07.2012)
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Journal Article
Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s
Chaudhry, Amarjit S, Thirumaran, Ranjit K, Yasuda, Kazuto, Yang, Xia, Fan, Yiping, Strom, Stephen C, Schuetz, Erin G
Published in Drug metabolism and disposition (01.08.2013)
Published in Drug metabolism and disposition (01.08.2013)
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Journal Article
Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction
Wang, YongQiang, Guan, Shenheng, Acharya, Poulomi, Liu, Yi, Thirumaran, Ranjit K, Brandman, Relly, Schuetz, Erin G, Burlingame, Alma L, Correia, Maria Almira
Published in Molecular & cellular proteomics (01.02.2012)
Published in Molecular & cellular proteomics (01.02.2012)
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Journal Article
The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans
Ilic, Katarina, Hawke, Roy L, Thirumaran, Ranjit K, Schuetz, Erin G, Hull, J Heyward, Kashuba, Angela D M, Stewart, Paul W, Lindley, Celeste M, Chen, Mei-Ling
Published in Drug metabolism and disposition (01.03.2013)
Published in Drug metabolism and disposition (01.03.2013)
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Journal Article
CYP450 genotyping and cumulative drug-gene interactions: an update for precision medicine
Thirumaran, Ranjit K, Heck, Jarrod W, Hocum, Brian T
Published in Personalized medicine (01.01.2016)
Published in Personalized medicine (01.01.2016)
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Journal Article
Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians
Brown, Kevin C, Hosseinipour, Mina C, Hoskins, Janelle M, Thirumaran, Ranjit K, Tien, Hsiao-Chuan, Weigel, Ralf, Tauzie, Jean, Shumba, Ida, Lamba, Jatinder K, Schuetz, Erin G, McLeod, Howard L, Kashuba, Angela D M, Corbett, Amanda H
Published in Pharmacogenomics (01.01.2012)
Published in Pharmacogenomics (01.01.2012)
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Journal Article
Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma
Figl, Adina, Scherer, Dominique, Nagore, Eduardo, Bermejo, Justo Lorenzo, Botella-Estrada, Rafael, Gast, Andreas, Thirumaran, Ranjit K., Planelles, Dolores, Hemminki, Kari, Schadendorf, Dirk, Kumar, Rajiv
Published in Mutation research (30.09.2010)
Published in Mutation research (30.09.2010)
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Journal Article
MTHFR genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia
Thirumaran, Ranjit K., Gast, Andreas, Flohr, Thomas, Burwinkel, Barbara, Bartram, Claus, Hemminki, Kari, Kumar, Rajiv
Published in Blood (01.10.2005)
Published in Blood (01.10.2005)
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Journal Article
Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin
Thirumaran, Ranjit Kumar, Bermejo, Justo Lorenzo, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Goessler, Walter, Vahter, Marie, Leonardi, Giovanni S., Clemens, Felicity, Fletcher, Tony, Hemminki, Kari, Kumar, Rajiv
Published in Carcinogenesis (New York) (01.08.2006)
Published in Carcinogenesis (New York) (01.08.2006)
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Journal Article
Multisite Phosphorylation of Human Liver Cytochrome P450 3A4 Enhances Its gp78- and CHIP-mediated Ubiquitination
Wang, YongQiang, Guan, Shenheng, Acharya, Poulomi, Liu, Yi, Thirumaran, Ranjit K., Brandman, Relly, Schuetz, Erin G., Burlingame, Alma L., Correia, Maria Almira
Published in Molecular & cellular proteomics (01.02.2012)
Published in Molecular & cellular proteomics (01.02.2012)
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Journal Article
Differential gene expression in melanocytic nevi with the V600E BRAF mutation
Bloethner, Sandra, Snellman, Erna, Bermejo, Justo Lorenzo, Hiripi, Eva, Gast, Andreas, Thirumaran, Ranjit K., Wellenreuther, Ruth, Hemminki, Kari, Kumar, Rajiv
Published in Genes chromosomes & cancer (01.11.2007)
Published in Genes chromosomes & cancer (01.11.2007)
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Journal Article