A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells
Harris, Katherine E., Lorentsen, Kyle J., Malik-Chaudhry, Harbani K., Loughlin, Kaitlyn, Basappa, Harish Medlari, Hartstein, Sharon, Ahmil, Ghenima, Allen, Nicole S., Avanzino, Brian C., Balasubramani, Aarti, Boudreau, Andrew A., Chang, Karen, Cuturi, Maria-Cristina, Davison, Laura M., Ho, Dennis M., Iyer, Suhasini, Rangaswamy, Udaya S., Sankaran, Preethi, Schellenberger, Ute, Buelow, Roland, Trinklein, Nathan D.
Published in Scientific reports (19.05.2021)
Published in Scientific reports (19.05.2021)
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Journal Article
TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL
Malik-Chaudhry, Harbani K, Prabhakar, Kirthana, Ugamraj, Harshad S, Boudreau, Andrew A, Buelow, Benjamin, Dang, Kevin, Davison, Laura M, Harris, Katherine E, Jorgensen, Brett, Ogana, Heather, Pham, Duy, Schellenberger, Ute, Van Schooten, Wim, Buelow, Roland, Iyer, Suhasini, Trinklein, Nathan D, Rangaswamy, Udaya S
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer
Avanzino, Brian C., Prabhakar, Kirthana, Dalvi, Pranjali, Hartstein, Sharon, Kehm, Hannes, Balasubramani, Aarti, Boudreau, Andrew A., Buelow, Ben, Chang, Karen, Davison, Laura M., Iyer, Suhasini, Kalwit, Vidyut, Lewis Wilson, Kristin, Malik-Chaudhry, Harbani K., Pierson, Will, Pineda, Geovanni, Rangaswamy, Udaya S., Saiganesh, Sowmya, Schellenberger, Ute, Ugamraj, Harshad S., Yabut, Rodolfovan D., Buelow, Roland, Chapman, Jocelyn, Trinklein, Nathan D., Harris, Katherine E.
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Journal Article
Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies
Harris, Katherine E, Aldred, Shelley Force, Davison, Laura M, Ogana, Heather Anne N, Boudreau, Andrew, Brüggemann, Marianne, Osborn, Michael, Ma, Biao, Buelow, Benjamin, Clarke, Starlynn C, Dang, Kevin H, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy T, Pratap, Payal P, Rangaswamy, Udaya S, Schellenberger, Ute, van Schooten, Wim C, Ugamraj, Harshad S, Vafa, Omid, Buelow, Roland, Trinklein, Nathan D
Published in Frontiers in immunology (24.04.2018)
Published in Frontiers in immunology (24.04.2018)
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Journal Article
Newcastle Disease Virus Establishes Persistent Infection in Tumor Cells In Vitro : Contribution of the Cleavage Site of Fusion Protein and Second Sialic Acid Binding Site of Hemagglutinin-Neuraminidase
Rangaswamy, Udaya S, Wang, Weijia, Cheng, Xing, McTamney, Patrick, Carroll, Danielle, Jin, Hong
Published in Journal of virology (15.08.2017)
Published in Journal of virology (15.08.2017)
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Journal Article
Evaluation of Newcastle disease virus mediated dendritic cell activation and cross‐priming tumor‐specific immune responses ex vivo
Xu, Qi, Rangaswamy, Udaya S., Wang, Weijia, Robbins, Scott H., Harper, James, Jin, Hong, Cheng, Xing
Published in International journal of cancer (15.01.2020)
Published in International journal of cancer (15.01.2020)
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Journal Article
Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies
Trinklein, Nathan D, Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C, Dang, Kevin, Harris, Katherine E, Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P, Rangaswamy, Udaya S, Ugamraj, Harshad S, Vafa, Omid, Wiita, Arun P, van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley
Published in mAbs (19.05.2019)
Published in mAbs (19.05.2019)
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Journal Article
Abstract 1554: Uncoupling tumor-cell cytotoxicity from cytokine release with novel T-cell engaging bispecific antibodies
Lorentsen, Kyle, Sankaran, Preethi, Trinklein, Nathan D., Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C., Dang, Kevin, Harris, Katherine E., Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal, Rangaswamy, Udaya S., Ugamraj, Harshad S., Vafa, Omid, Wiita, Arun P., Schooten, Wim van, Buelow, Roland, Aldred, Shelley Force
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 6244: A T cell engaging bispecific antibody utilizing a bivalent tumor-selective folate receptor alpha binding arm for the treatment of ovarian cancer
Avanzino, Brian C., Prabhakar, Kirthana, Dalvi, Pranjali, Hartstein, Sharon, Kehm, Hannes, Balasubramani, Aarti, Boudreau, Andrew A., Buelow, Ben, Chang, Karen, Davison, Laura M., Iyer, Suhasini, Kalwit, Vidyut, Malik-Chaudhry, Harbani, Pierson, Will, Pineda, Geovanni, Rangaswamy, Udaya S., Saiganesh, Sowmya, Schellenberger, Ute, Ugamraj, Harshad S., Buelow, Roland, Chapman, Jocelyn, Trinklein, Nathan D., Harris, Katherine E.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL
Malik-Chaudhry, Harbani K., Prabhakar, Kirthana, Ugamraj, Harshad S., Boudreau, Andrew A., Buelow, Benjamin, Dang, Kevin, Davison, Laura M., Harris, Katherine E., Jorgensen, Brett, Ogana, Heather, Pham, Duy, Schellenberger, Ute, Van Schooten, Wim, Buelow, Roland, Iyer, Suhasini, Trinklein, Nathan D., Rangaswamy, Udaya S.
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Report
Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies
Trinklein, Nathan D., Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C., Dang, Kevin, Harris, Katherine E., Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P., Rangaswamy, Udaya S., Ugamraj, Harshad S., Vafa, Omid, Wiita, Arun P., van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley
Published in mAbs (19.05.2019)
Published in mAbs (19.05.2019)
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Multi-specific heavy chain antibodies that bind to CD22 and CD3
TRINKLEIN NATHAN, PRABHAKAR KARTHIK, UGAMARAJ HARISH, RANGASWAMY UDAYA, IYER SURESH
Year of Publication 18.03.2022
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Year of Publication 18.03.2022
Patent
Heavy chain antibodies that bind to CD19
TRINKLEIN NATHAN, HARRIS KATHERINE, ALDRED SHELLEY FORCE, RANGASWAMY UDAYA, VAN SCHOOTEN WIM
Year of Publication 19.09.2023
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Year of Publication 19.09.2023
Patent
Multispecific heavy chain antibodies binding to CD22 and CD3
IYER, SUHASINI, PRABHAKAR, KIRTHANA, RANGASWAMY, UDAYA, TRINKLEIN, NATHAN, UGAMRAJ, HARSHAD
Year of Publication 01.03.2021
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Year of Publication 01.03.2021
Patent
HEAVY CHAIN ANTIBODIES BINDING TO CD19
TRINKLEIN NATHAN, HARRIS KATHERINE, ALDRED SHELLEY FORCE, RANGASWAMY UDAYA, VAN SCHOOTEN WIM
Year of Publication 09.02.2021
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Year of Publication 09.02.2021
Patent