Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria
Ranganath, L. R., Milan, A. M., Hughes, A. T., Davison, A. S., M, Khedr, Norman, B. P., Bou-Gharios, G., Gallagher, J. A., Imrich, R., Arnoux, J. B., Rudebeck, M., Olsson, B.
Published in Scientific reports (27.09.2022)
Published in Scientific reports (27.09.2022)
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Journal Article
The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria
Taylor, A. M., Boyde, A., Wilson, P. J. M., Jarvis, J. C., Davidson, J. S., Hunt, J. A., Ranganath, L. R., Gallagher, J. A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2011)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2011)
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Journal Article
Evaluating the aortic stenosis phenotype before and after the effect of homogentisic acid lowering therapy: Analysis of a large cohort of eighty-one alkaptonuria patients
Ranganath, L.R., Heseltine, T., Khedr, M., Fisher, M.F.
Published in Molecular genetics and metabolism (01.07.2021)
Published in Molecular genetics and metabolism (01.07.2021)
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Journal Article
Alkaptonuria - Many questions answered, further challenges beckon
Davison, A S, Hughes, A T, Milan, A M, Sireau, N, Gallagher, J A, Ranganath, L R
Published in Annals of clinical biochemistry (01.03.2020)
Published in Annals of clinical biochemistry (01.03.2020)
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Journal Article
Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre
Ranganath, L.R., Khedr, M., Milan, A.M., Davison, A.S., Hughes, A.T., Usher, J.L., Taylor, S., Loftus, N., Daroszewska, A., West, E., Jones, A., Briggs, M., Fisher, M., McCormick, M., Judd, S., Vinjamuri, S., Griffin, R., Psarelli, E.E., Cox, T.F., Sireau, N., Dillon, J.P., Devine, J.M., Hughes, G., Harrold, J., Barton, G.J., Jarvis, J.C., Gallagher, J.A.
Published in Molecular genetics and metabolism (01.09.2018)
Published in Molecular genetics and metabolism (01.09.2018)
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Journal Article
Identifying joint-specific gait mechanisms causing impaired gait in alkaptonuria patients
Shepherd, H.R., Robinson, M.A., Ranganath, L.R., Barton, G.J.
Published in Gait & posture (01.01.2022)
Published in Gait & posture (01.01.2022)
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Journal Article
Anthropometric, Body Composition, and Nutritional Indicators with and without Nutritional Intervention during Nitisinone Therapy in Alkaptonuria
Ranganath, L R, Khedr, M, Milan, A M, Davison, A S, Hughes, A T, Norman, B P, Bygott, H, Luangrath, E, Judd, S, Soulsby, C, Olsson, B, Imrich, R
Published in Nutrients (15.08.2024)
Published in Nutrients (15.08.2024)
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Journal Article
Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria
Norman, B. P., Sutherland, H., Wilson, P. J. M., Rutland, D. A., Milan, A. M., Hughes, A. T., Davison, A. S., Khedr, M., Jarvis, J. C., Gallagher, J. A., Bou‐Gharios, G., Ranganath, L. R.
Published in Journal of inherited metabolic disease (01.07.2024)
Published in Journal of inherited metabolic disease (01.07.2024)
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Journal Article
Quantification of the flux of tyrosine pathway metabolites during nitisinone treatment of Alkaptonuria
Milan, A M, Hughes, A T, Davison, A S, Khedr, M, Rovensky, J, Psarelli, E E, Cox, T F, Rhodes, N P, Gallagher, J A, Ranganath, L R
Published in Scientific reports (11.07.2019)
Published in Scientific reports (11.07.2019)
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Journal Article
Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project
Braconi, D., Giustarini, D., Marzocchi, B., Peruzzi, L., Margollicci, M., Rossi, R., Bernardini, G., Millucci, L., Gallagher, J.A., Le Quan Sang, K.-H., Imrich, R., Rovensky, J., Al-Sbou, M., Ranganath, L.R., Santucci, A.
Published in Osteoarthritis and cartilage (01.08.2018)
Published in Osteoarthritis and cartilage (01.08.2018)
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Journal Article
Acute fatal metabolic complications in alkaptonuria
Davison, A. S., Milan, A. M., Gallagher, J. A., Ranganath, L. R.
Published in Journal of Inherited Metabolic Disease (01.03.2016)
Published in Journal of Inherited Metabolic Disease (01.03.2016)
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Book Review
Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis
Taylor, A.M., Jenks, D.D., Kammath, V.D., Norman, B.P., Dillon, J.P., Gallagher, J.A., Ranganath, L.R., Kerns, J.G.
Published in Osteoarthritis and cartilage (01.08.2019)
Published in Osteoarthritis and cartilage (01.08.2019)
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Journal Article
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging
Davison, A. S., Strittmatter, N., Sutherland, H., Hughes, A. T., Hughes, J., Bou-Gharios, G., Milan, A. M., Goodwin, R. J. A., Ranganath, L. R., Gallagher, J. A.
Published in Metabolomics (01.05.2019)
Published in Metabolomics (01.05.2019)
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Journal Article
Urine homogentisic acid and tyrosine: Simultaneous analysis by liquid chromatography tandem mass spectrometry
Hughes, A.T., Milan, A.M., Christensen, P., Ross, G., Davison, A.S., Gallagher, J.A., Dutton, J.J., Ranganath, L.R.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.07.2014)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.07.2014)
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Journal Article
Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone
Davison, A.S., Harrold, J.A., Hughes, G., Norman, B.P., Devine, J., Usher, J., Hughes, A.T., Khedr, M., Gallagher, J.A., Milan, A.M., J.C.G., Halford, Ranganath, L.R.
Published in Molecular genetics and metabolism (01.09.2018)
Published in Molecular genetics and metabolism (01.09.2018)
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