Autophagy and p62 in Cardiac Proteinopathy
Zheng, Qingwen, Su, Huabo, Ranek, Mark J, Wang, Xuejun
Published in Circulation research (22.07.2011)
Published in Circulation research (22.07.2011)
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Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
Lee, Dong I., Zhu, Guangshuo, Sasaki, Takashi, Cho, Gun-Sik, Hamdani, Nazha, Holewinski, Ronald, Jo, Su-Hyun, Danner, Thomas, Zhang, Manling, Rainer, Peter P., Bedja, Djahida, Kirk, Jonathan A., Ranek, Mark J., Dostmann, Wolfgang R., Kwon, Chulan, Margulies, Kenneth B., Van Eyk, Jennifer E., Paulus, Walter J., Takimoto, Eiki, Kass, David A.
Published in Nature (London) (26.03.2015)
Published in Nature (London) (26.03.2015)
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COP9 Signalosome Regulates Autophagosome Maturation
HUABO SU, FAQIAN LI, RANEK, Mark J, NING WEI, XUEJUN WANG
Published in Circulation (New York, N.Y.) (08.11.2011)
Published in Circulation (New York, N.Y.) (08.11.2011)
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In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease
Lin, Brian Leei, Matera, Damian, Doerner, Julia F., Zheng, Nan, del Camino, Donato, Mishra, Sumita, Bian, Hong, Zeveleva, Svetlana, Zhen, Xiaoguang, Blair, Nathaniel T., Chong, Jayhong A., Hessler, David P., Bedja, Djahida, Zhu, Guangshuo, Muller, Grace K., Ranek, Mark J., Pantages, Lynn, McFarland, Mary, Netherton, Matthew R., Berry, Angela, Wong, Diane, Rast, Georg, Qian, Hu Sheng, Weldon, Steven M., Kuo, Jay J., Sauer, Achim, Sarko, Chris, Moran, Magdalene M., Kass, David A., Pullen, Steven S.
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
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Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
Zhang, Qing-Jun, Tran, Tram Anh T., Wang, Ming, Ranek, Mark J., Kokkonen-Simon, Kristen M., Gao, Jason, Luo, Xiang, Tan, Wei, Kyrychenko, Viktoriia, Liao, Lan, Xu, Jianming, Hill, Joseph A., Olson, Eric N., Kass, David A., Martinez, Elisabeth D., Liu, Zhi-Ping
Published in Nature communications (07.12.2018)
Published in Nature communications (07.12.2018)
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CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury
Ranek, Mark J., Oeing, Christian, Sanchez-Hodge, Rebekah, Kokkonen-Simon, Kristen M., Dillard, Danielle, Aslam, M. Imran, Rainer, Peter P., Mishra, Sumita, Dunkerly-Eyring, Brittany, Holewinski, Ronald J., Virus, Cornelia, Zhang, Huaqun, Mannion, Matthew M., Agrawal, Vineet, Hahn, Virginia, Lee, Dong I., Sasaki, Masayuki, Van Eyk, Jennifer E., Willis, Monte S., Page, Richard C., Schisler, Jonathan C., Kass, David A.
Published in Nature communications (20.10.2020)
Published in Nature communications (20.10.2020)
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Protein Kinase G Positively Regulates Proteasome-Mediated Degradation of Misfolded Proteins
Ranek, Mark J, Terpstra, Erin J.M, Li, Jie, Kass, David A, Wang, Xuejun
Published in Circulation (New York, N.Y.) (23.07.2013)
Published in Circulation (New York, N.Y.) (23.07.2013)
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Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction
Ngkelo, Anta, Richart, Adèle, Kirk, Jonathan A, Bonnin, Philippe, Vilar, Jose, Lemitre, Mathilde, Marck, Pauline, Branchereau, Maxime, Le Gall, Sylvain, Renault, Nisa, Guerin, Coralie, Ranek, Mark J, Kervadec, Anaïs, Danelli, Luca, Gautier, Gregory, Blank, Ulrich, Launay, Pierre, Camerer, Eric, Bruneval, Patrick, Menasche, Philippe, Heymes, Christophe, Luche, Elodie, Casteilla, Louis, Cousin, Béatrice, Rodewald, Hans-Reimer, Kass, David A, Silvestre, Jean-Sébastien
Published in The Journal of experimental medicine (27.06.2016)
Published in The Journal of experimental medicine (27.06.2016)
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Editorial: Targeting Cardiac Proteotoxicity
Ranek, Mark J, Bhuiyan, Md Shenuarin, Wang, Xuejun
Published in Frontiers in physiology (25.03.2021)
Published in Frontiers in physiology (25.03.2021)
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Journal Article
Targeting Protein Kinase G to Treat Cardiac Proteotoxicity
Oeing, Christian U., Mishra, Sumita, Dunkerly-Eyring, Brittany L., Ranek, Mark J.
Published in Frontiers in physiology (28.07.2020)
Published in Frontiers in physiology (28.07.2020)
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Phosphorylation Modifications Regulating Cardiac Protein Quality Control Mechanisms
Mishra, Sumita, Dunkerly-Eyring, Brittany L, Keceli, Gizem, Ranek, Mark J
Published in Frontiers in physiology (12.11.2020)
Published in Frontiers in physiology (12.11.2020)
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Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at Threonine-221 plays potent role in channel regulation
Mishra, Sumita, Ma, Junfeng, McKoy, Desirae, Sasaki, Masayuki, Farinelli, Federica, Page, Richard C., Ranek, Mark J., Zachara, Natasha, Kass, David A.
Published in iScience (17.03.2023)
Published in iScience (17.03.2023)
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TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy
Patel, Chirag H, Dong, Yi, Koleini, Navid, Wang, Xiaoxu, Dunkerly-Eyring, Brittany L, Wen, Jiayu, Ranek, Mark J, Bartle, Laura M, Henderson, Daniel B, Sagert, Jason, Kass, David A, Powell, Jonathan D
Published in JCI insight (08.11.2023)
Published in JCI insight (08.11.2023)
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Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease
Kokkonen-Simon, Kristen M, Saberi, Amir, Nakamura, Taishi, Ranek, Mark J, Zhu, Guangshuo, Bedja, Djahida, Kuhn, Michaela, Halushka, Marc K, Lee, Dong Ik, Kass, David A
Published in JCI insight (09.08.2018)
Published in JCI insight (09.08.2018)
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Phosphodiesterases: Evolving Concepts and Implications for Human Therapeutics
Kelly, Evan D, Ranek, Mark J, Zhang, Manling, Kass, David A, Muller, Grace K
Published in Annual review of pharmacology and toxicology (25.09.2024)
Published in Annual review of pharmacology and toxicology (25.09.2024)
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PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress
Ranek, Mark J., Kokkonen-Simon, Kristen M., Chen, Anna, Dunkerly-Eyring, Brittany L., Vera, Miguel Pinilla, Oeing, Christian U., Patel, Chirag H., Nakamura, Taishi, Zhu, Guangshuo, Bedja, Djahida, Sasaki, Masayuki, Holewinski, Ronald J., Van Eyk, Jennifer E., Powell, Jonathan D., Lee, Dong Ik, Kass, David A.
Published in Nature (London) (01.02.2019)
Published in Nature (London) (01.02.2019)
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