GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees
Lanford, Robert E, Guerra, Bernadette, Chavez, Deborah, Giavedoni, Luis, Hodara, Vida L, Brasky, Kathleen M, Fosdick, Abigail, Frey, Christian R, Zheng, Jim, Wolfgang, Grushenka, Halcomb, Randall L, Tumas, Daniel B
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2013)
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Pharmacokinetic and pharmacodynamic properties of GS-9620, a novel Toll-like receptor 7 agonist, demonstrate interferon-stimulated gene induction without detectable serum interferon at low oral doses
Fosdick, Abigail, Zheng, Jim, Pflanz, Stefan, Frey, Christian R, Hesselgesser, Joseph, Halcomb, Randall L, Wolfgang, Grushenka, Tumas, Daniel B
Published in The Journal of pharmacology and experimental therapeutics (01.01.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2014)
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Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis
Roethle, Paul A, McFadden, Ryan M, Yang, Hong, Hrvatin, Paul, Hui, Hon, Graupe, Michael, Gallagher, Brian, Chao, Jessica, Hesselgesser, Joseph, Duatschek, Paul, Zheng, Jim, Lu, Bing, Tumas, Daniel B, Perry, Jason, Halcomb, Randall L
Published in Journal of medicinal chemistry (26.09.2013)
Published in Journal of medicinal chemistry (26.09.2013)
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Total Synthesis of (+)-Phomactin A Using a B-Alkyl Suzuki Macrocyclization
Mohr, Peter J, Halcomb, Randall L
Published in Journal of the American Chemical Society (19.02.2003)
Published in Journal of the American Chemical Society (19.02.2003)
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Design and Synthesis of Conformationally Constrained Glycosylated Amino Acids
Koviach, Jennifer L, Chappell, Mark D, Halcomb, Randall L
Published in Journal of organic chemistry (06.04.2001)
Published in Journal of organic chemistry (06.04.2001)
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Ligand Recognition by E-Selectin: Synthesis, Inhibitory Activity and Conformational Analysis of Bivalent Sialyl Lewis x Analogs
DeFrees, Shawn A, Kosch, Winfried, Way, William, Paulson, James C, Sabesan, Subramanian, Halcomb, Randall L, Huang, Dee-Hua, Ichikawa, Yoshitaka, Wong, Chi-Huey
Published in Journal of the American Chemical Society (1995)
Published in Journal of the American Chemical Society (1995)
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Antibody–Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs
Behrens, Christopher R, Ha, Edward H, Chinn, Lawrence L, Bowers, Simeon, Probst, Gary, Fitch-Bruhns, Maureen, Monteon, Jorge, Valdiosera, Amanda, Bermudez, Abel, Liao-Chan, Sindy, Wong, Tiffany, Melnick, Jonathan, Theunissen, Jan-Willem, Flory, Mark R, Houser, Derrick, Venstrom, Kristy, Levashova, Zoia, Sauer, Paul, Migone, Thi-Sau, van der Horst, Edward H, Halcomb, Randall L, Jackson, David Y
Published in Molecular pharmaceutics (02.11.2015)
Published in Molecular pharmaceutics (02.11.2015)
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Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase α
Kincaid, Kristi, Beckman, Jeff, Zivkovic, Aleksandra, Halcomb, Randall L., Engels, Joachim W., Kuchta, Robert D.
Published in Nucleic acids research (2005)
Published in Nucleic acids research (2005)
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On the conversion of biologically interesting amines to hydroxylamines
Wittman, Mark D, Halcomb, Randall L, Danishefsky, Samuel J
Published in Journal of organic chemistry (01.03.1990)
Published in Journal of organic chemistry (01.03.1990)
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