Mechanisms, regulation and functions of the unfolded protein response
Hetz, Claudio, Zhang, Kezhong, Kaufman, Randal J.
Published in Nature reviews. Molecular cell biology (01.08.2020)
Published in Nature reviews. Molecular cell biology (01.08.2020)
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ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development
Nakagawa, Hayato, Umemura, Atsushi, Taniguchi, Koji, Font-Burgada, Joan, Dhar, Debanjan, Ogata, Hisanobu, Zhong, Zhenyu, Valasek, Mark A., Seki, Ekihiro, Hidalgo, Juan, Koike, Kazuhiko, Kaufman, Randal J., Karin, Michael
Published in Cancer cell (08.09.2014)
Published in Cancer cell (08.09.2014)
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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
Han, Jaeseok, Back, Sung Hoon, Hur, Junguk, Lin, Yu-Hsuan, Gildersleeve, Robert, Shan, Jixiu, Yuan, Celvie L., Krokowski, Dawid, Wang, Shiyu, Hatzoglou, Maria, Kilberg, Michael S., Sartor, Maureen A., Kaufman, Randal J.
Published in Nature cell biology (01.05.2013)
Published in Nature cell biology (01.05.2013)
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Targeting endoplasmic reticulum stress in metabolic disease
Cao, Stewart Siyan, Kaufman, Randal J
Published in Expert opinion on therapeutic targets (01.04.2013)
Published in Expert opinion on therapeutic targets (01.04.2013)
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Journal Article
Biosynthesis, structure, and folding of the insulin precursor protein
Liu, Ming, Weiss, Michael A., Arunagiri, Anoop, Yong, Jing, Rege, Nischay, Sun, Jinhong, Haataja, Leena, Kaufman, Randal J., Arvan, Peter
Published in Diabetes, obesity & metabolism (01.09.2018)
Published in Diabetes, obesity & metabolism (01.09.2018)
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Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome
Oslowski, Christine M., Hara, Takashi, O'Sullivan-Murphy, Bryan, Kanekura, Kohsuke, Lu, Simin, Hara, Mariko, Ishigaki, Shinsuke, Zhu, Lihua J., Hayashi, Emiko, Hui, Simon T., Greiner, Dale, Kaufman, Randal J., Bortell, Rita, Urano, Fumihiko
Published in Cell metabolism (08.08.2012)
Published in Cell metabolism (08.08.2012)
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ER stress and inflammation crosstalk in obesity
Ajoolabady, Amir, Lebeaupin, Cynthia, Wu, Ne N., Kaufman, Randal J., Ren, Jun
Published in Medicinal research reviews (01.01.2023)
Published in Medicinal research reviews (01.01.2023)
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Maternal immune activation in mice disrupts proteostasis in the fetal brain
Kalish, Brian T., Kim, Eunha, Finander, Benjamin, Duffy, Erin E., Kim, Hyunju, Gilman, Casey K., Yim, Yeong Shin, Tong, Lilin, Kaufman, Randal J., Griffith, Eric C., Choi, Gloria B., Greenberg, Michael E., Huh, Jun R.
Published in Nature neuroscience (01.02.2021)
Published in Nature neuroscience (01.02.2021)
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IRE1α-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis
Wang, Shiyu, Chen, Zhouji, Lam, Vivian, Han, Jaeseok, Hassler, Justin, Finck, Brian N., Davidson, Nicholas O., Kaufman, Randal J.
Published in Cell metabolism (03.10.2012)
Published in Cell metabolism (03.10.2012)
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Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice
Li, Yan, Tinoco, Roberto, Elmén, Lisa, Segota, Igor, Xian, Yibo, Fujita, Yu, Sahu, Avinash, Zarecki, Raphy, Marie, Kerrie, Feng, Yongmei, Khateb, Ali, Frederick, Dennie T., Ashkenazi, Shiri K., Kim, Hyungsoo, Perez, Eva Guijarro, Day, Chi-Ping, Segura Muñoz, Rafael S., Schmaltz, Robert, Yooseph, Shibu, Tam, Miguel A., Zhang, Tongwu, Avitan-Hersh, Emily, Tzur, Lihi, Roizman, Shoshana, Boyango, Ilanit, Bar-Sela, Gil, Orian, Amir, Kaufman, Randal J., Bosenberg, Marcus, Goding, Colin R., Baaten, Bas, Levesque, Mitchell P., Dummer, Reinhard, Brown, Kevin, Merlino, Glenn, Ruppin, Eytan, Flaherty, Keith, Ramer-Tait, Amanda, Long, Tao, Peterson, Scott N., Bradley, Linda M., Ronai, Ze’ev A.
Published in Nature communications (02.04.2019)
Published in Nature communications (02.04.2019)
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The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice
Cao, Stewart Siyan, Zimmermann, Ellen M, Chuang, Brandy–Mengchieh, Song, Benbo, Nwokoye, Anosike, Wilkinson, J. Erby, Eaton, Kathryn A, Kaufman, Randal J
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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