Leveraging Chemotype-Specific Resistance for Drug Target Identification and Chemical Biology
Kapoor, Tarun M., Miller, Rand M.
Published in Trends in pharmacological sciences (Regular ed.) (01.12.2017)
Published in Trends in pharmacological sciences (Regular ed.) (01.12.2017)
Get full text
Journal Article
Covalent docking of large libraries for the discovery of chemical probes
London, Nir, Miller, Rand M, Krishnan, Shyam, Uchida, Kenji, Irwin, John J, Eidam, Oliv, Gibold, Lucie, Cimermančič, Peter, Bonnet, Richard, Shoichet, Brian K, Taunton, Jack
Published in Nature chemical biology (01.12.2014)
Published in Nature chemical biology (01.12.2014)
Get full text
Journal Article
Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription
Josefowicz, Steven Z., Shimada, Miho, Armache, Anja, Li, Charles H., Miller, Rand M., Lin, Shu, Yang, Aerin, Dill, Brian D., Molina, Henrik, Park, Hee-Sung, Garcia, Benjamin A., Taunton, Jack, Roeder, Robert G., Allis, C. David
Published in Molecular cell (20.10.2016)
Published in Molecular cell (20.10.2016)
Get full text
Journal Article
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
Serafimova, Iana M, Pufall, Miles A, Krishnan, Shyam, Duda, Katarzyna, Cohen, Michael S, Maglathlin, Rebecca L, McFarland, Jesse M, Miller, Rand M, Frödin, Morten, Taunton, Jack
Published in Nature chemical biology (01.04.2012)
Published in Nature chemical biology (01.04.2012)
Get full text
Journal Article
WRN inhibition leads to its chromatin-associated degradation via the PIAS4-RNF4-p97/VCP axis
Rodríguez Pérez, Fernando, Natwick, Dean, Schiff, Lauren, McSwiggen, David, Heckert, Alec, Huey, Melina, Morrison, Huntly, Loo, Mandy, Miranda, Rafael G., Filbin, John, Ortega, Jose, Van Buren, Kayla, Murnock, Danny, Tao, Arnold, Butler, Renee, Cheng, Kylie, Tarvestad, William, Zhang, Zhengjian, Gonzalez, Eric, Miller, Rand M., Kelly, Marcus, Tang, Yangzhong, Ho, Jaclyn, Anderson, Daniel, Bashore, Charlene, Basham, Stephen
Published in Nature communications (18.07.2024)
Published in Nature communications (18.07.2024)
Get full text
Journal Article
Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action
Steinman, Jonathan B, Santarossa, Cristina C, Miller, Rand M, Yu, Lola S, Serpinskaya, Anna S, Furukawa, Hideki, Morimoto, Sachie, Tanaka, Yuta, Nishitani, Mitsuyoshi, Asano, Moriteru, Zalyte, Ruta, Ondrus, Alison E, Johnson, Alex G, Ye, Fan, Nachury, Maxence V, Fukase, Yoshiyuki, Aso, Kazuyoshi, Foley, Michael A, Gelfand, Vladimir I, Chen, James K, Carter, Andrew P, Kapoor, Tarun M
Published in eLife (19.05.2017)
Published in eLife (19.05.2017)
Get full text
Journal Article
Correction to “Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis”
Krishnan, Shyam, Miller, Rand M, Tian, Boxue, Mullins, R. Dyche, Jacobson, Matthew P, Taunton, Jack
Published in Journal of the American Chemical Society (17.12.2014)
Published in Journal of the American Chemical Society (17.12.2014)
Get full text
Journal Article
Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity
See, Stephanie K., Hoogendoorn, Sascha, Chung, Andrew H., Ye, Fan, Steinman, Jonathan B., Sakata-Kato, Tomoyo, Miller, Rand M., Cupido, Tommaso, Zalyte, Ruta, Carter, Andrew P., Nachury, Maxence V., Kapoor, Tarun M., Chen, James K.
Published in ACS chemical biology (15.01.2016)
Published in ACS chemical biology (15.01.2016)
Get full text
Journal Article
Targeting chromatin kinases reveals their role in inducible transcription of inflammatory genes
Josefowicz, Steven, Shimada, Miho, Armache, Anja, Li, Charles, Miller, Rand, Lin, Shu, Garcia, Benjamin, Taunton, Jack, Roeder, Robert, Allis, David
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
Get full text
Journal Article
Covalent Docking of Large Libraries for the Discovery of Chemical Probes
London, Nir, Miller, Rand M., Irwin, John J., Eidam, Oliv, Gibold, Lucie, Bonnet, Richard, Shoichet, Brian K., Taunton, Jack
Published in Biophysical journal (28.01.2014)
Published in Biophysical journal (28.01.2014)
Get full text
Journal Article
Erratum: Covalent docking of large libraries for the discovery of chemical probes
London, Nir, Miller, Rand M, Krishnan, Shyam, Uchida, Kenji, Irwin, John J, Eidam, Oliv, Gibold, Lucie, Cimermančič, Peter, Bonnet, Richard, Shoichet, Brian K, Taunton, Jack
Published in Nature chemical biology (01.03.2015)
Published in Nature chemical biology (01.03.2015)
Get full text
Journal Article
WRN Inhibition Leads to its Chromatin-Associated Degradation Via the PIAS4-RNF4-p97/VCP Axis
Fernando Rodríguez Pérez, Natwick, Dean E, Schiff, Lauren, Huey, Melina, Mcswiggen, David, Heckert, Alec, Ortega, Jose, Loo, Mandy, Miranda, Rafael, Morrison, Huntly M, Butler, Renee, Cheng, Kylie, Filbin, John, Gonzalez, Eric, Miller, Rand, Tang, Yangzhong, Ho, Jaclyn J, Zhang, Zhanegjiang, Anderson, Daniel J, Bashore, Charlene, Basham, Steve
Published in bioRxiv (09.12.2023)
Published in bioRxiv (09.12.2023)
Get full text
Paper
Kinase inhibitors
Miller Rand, Taunton, Jr. John William, Maglathlin Rebecca, McFarland Jesse, Serafimova Iana, Cohen Michael S, Krishnan Shyam, Paavilainen Ville
Year of Publication 29.11.2016
Get full text
Year of Publication 29.11.2016
Patent