Pd-Catalyzed Enantioselective Aerobic Oxidation of Secondary Alcohols: Applications to the Total Synthesis of Alkaloids
Krishnan, Shyam, Bagdanoff, Jeffrey T, Ebner, David C, Ramtohul, Yeeman K, Tambar, Uttam K, Stoltz, Brian M
Published in Journal of the American Chemical Society (15.10.2008)
Published in Journal of the American Chemical Society (15.10.2008)
Get full text
Journal Article
Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia
Oballa, Renata M, Belair, Liette, Black, W. Cameron, Bleasby, Kelly, Chan, Chi Chung, Desroches, Carole, Du, Xiaobing, Gordon, Robert, Guay, Jocelyne, Guiral, Sebastien, Hafey, Michael J, Hamelin, Emelie, Huang, Zheng, Kennedy, Brian, Lachance, Nicolas, Landry, France, Li, Chun Sing, Mancini, Joseph, Normandin, Denis, Pocai, Alessandro, Powell, David A, Ramtohul, Yeeman K, Skorey, Kathryn, Sørensen, Dan, Sturkenboom, Wayne, Styhler, Angela, Waddleton, Deena M, Wang, Hao, Wong, Simon, Xu, Lijing, Zhang, Lei
Published in Journal of medicinal chemistry (28.07.2011)
Published in Journal of medicinal chemistry (28.07.2011)
Get full text
Journal Article
Palladium-Catalyzed Oxidative Wacker Cyclizations in Nonpolar Organic Solvents with Molecular Oxygen: A Stepping Stone to Asymmetric Aerobic Cyclizations
Trend, Raissa M., Ramtohul, Yeeman K., Ferreira, Eric M., Stoltz, Brian M.
Published in Angewandte Chemie (International ed.) (30.06.2003)
Published in Angewandte Chemie (International ed.) (30.06.2003)
Get full text
Journal Article
Thiazole analog as stearoyl-CoA desaturase 1 inhibitor
Li, Chun Sing, Belair, Liette, Guay, Jocelyne, Murgasva, Renata, Sturkenboom, Wayne, Ramtohul, Yeeman K., Zhang, Lei, Huang, Zheng
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Get full text
Journal Article
Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series
Lachance, Nicolas, Gareau, Yves, Guiral, Sébastien, Huang, Zheng, Isabel, Elise, Leclerc, Jean-Philippe, Léger, Serge, Martins, Evelyn, Nadeau, Christian, Oballa, Renata M., Ouellet, Stéphane G., Powell, David A., Ramtohul, Yeeman K., Tranmer, Geoffrey K., Trinh, Thao, Wang, Hao, Zhang, Lei
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Get full text
Journal Article
SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors
Ramtohul, Yeeman K., Black, Cameron, Chan, Chi-Chung, Crane, Sheldon, Guay, Jocelyne, Guiral, Sébastien, Huang, Zheng, Oballa, Renata, Xu, Li-Jing, Zhang, Lei, Li, Chun Sing
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Get full text
Journal Article
Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: From systemic to liver-targeting inhibitors
Ramtohul, Yeeman K., Powell, David, Leclerc, Jean-Philippe, Leger, Serge, Oballa, Renata, Black, Cameron, Isabel, Elise, Li, Chun Sing, Crane, Sheldon, Robichaud, Joel, Guay, Jocelyne, Guiral, Sébastien, Zhang, Lei, Huang, Zheng
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Get full text
Journal Article
Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series
Lachance, Nicolas, Guiral, Sébastien, Huang, Zheng, Leclerc, Jean-Philippe, Li, Chun Sing, Oballa, Renata M., Ramtohul, Yeeman K., Wang, Hao, Wu, Jin, Zhang, Lei
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Get full text
Journal Article
Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors
Leclerc, Jean-Philippe, Falgueyret, Jean-Pierre, Girardin, Mélina, Guay, Jocelyne, Guiral, Sébastien, Huang, Zheng, Li, Chun Sing, Oballa, Renata, Ramtohul, Yeeman K., Skorey, Kathryn, Tawa, Paul, Wang, Hao, Zhang, Lei
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Get full text
Journal Article
Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics
Tan, Christopher M, Therien, Alex G, Lu, Jun, Lee, Sang H, Caron, Alexandre, Gill, Charles J, Lebeau-Jacob, Christian, Benton-Perdomo, Liliana, Monteiro, João M, Pereira, Pedro M, Elsen, Nathaniel L, Wu, Jin, Deschamps, Kathleen, Petcu, Mihai, Wong, Simon, Daigneault, Etienne, Kramer, Susanne, Liang, Lianzhu, Maxwell, Eugene, Claveau, David, Vaillancourt, John, Skorey, Kathryn, Tam, John, Wang, Hao, Meredith, Timothy C, Sillaots, Susan, Wang-Jarantow, Lisa, Ramtohul, Yeeman, Langlois, Eric, Landry, France, Reid, John C, Parthasarathy, Gopal, Sharma, Sujata, Baryshnikova, Anastasia, Lumb, Kevin J, Pinho, Mariana G, Soisson, Stephen M, Roemer, Terry
Published in Science translational medicine (21.03.2012)
Published in Science translational medicine (21.03.2012)
Get more information
Journal Article
낭성 섬유증 막관통 전도도 조절제로서 사용하기 위한 1,3,4-옥사디아졸 고리를 함유하는 거대환
HADIDA RUAH SARA SABINA, BECHARA WILLIAM SCHULZ, COON TIMOTHY, RAMTOHUL YEEMAN K, ZHOU JINGLAN, BOOKSER BRETT C, VALDEZ LINO, GROOTENHUIS PETER DIEDERIK JAN, LATERREUR JULIE, PARASELLI PRASUNA, BAEK MINSON, STURINO CLAUDIO, CLEVELAND THOMAS, GALLANT MICHEL, REDDY THUMKUNTA JAGADEESWAR, MILLER MARK THOMAS, CLEMENS JEREMY J
Year of Publication 23.08.2023
Get full text
Year of Publication 23.08.2023
Patent
Synthesis of pseudoxazolones and their inhibition of the 3C cysteine proteinases from hepatitis A virus and human rhinovirus-14
Ramtohul, YK, Martin, NI, Silkin, L, James, MNG, Vederas, JC
Published in Perkin 1 : an international journal of organic and bio-organic chemistry (23.05.2002)
Published in Perkin 1 : an international journal of organic and bio-organic chemistry (23.05.2002)
Get more information
Journal Article