A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity
Swaney, Danielle L, Ramms, Dana J, Wang, Zhiyong, Park, Jisoo, Goto, Yusuke, Soucheray, Margaret, Bhola, Neil, Kim, Kyumin, Zheng, Fan, Zeng, Yan, McGregor, Michael, Herrington, Kari A, O'Keefe, Rachel, Jin, Nan, VanLandingham, Nathan K, Foussard, Helene, Von Dollen, John, Bouhaddou, Mehdi, Jimenez-Morales, David, Obernier, Kirsten, Kreisberg, Jason F, Kim, Minkyu, Johnson, Daniel E, Jura, Natalia, Grandis, Jennifer R, Gutkind, J Silvio, Ideker, Trey, Krogan, Nevan J
Published in Science (American Association for the Advancement of Science) (01.10.2021)
Published in Science (American Association for the Advancement of Science) (01.10.2021)
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G α s-Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant G α s-PKA Signaling
Ramms, Dana J, Raimondi, Francesco, Arang, Nadia, Herberg, Friedrich W, Taylor, Susan S, Gutkind, J Silvio
Published in Pharmacological reviews (01.10.2021)
Published in Pharmacological reviews (01.10.2021)
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Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carcinoma with Limited irAEs
Gilardi, Mara, Saddawi-Konefka, Robert, Wu, Victoria H, Lopez-Ramirez, Miguel Angel, Wang, Zhiyong, Soto, Fernando, Ramms, Dana J, Proietto, Marco, Mikulski, Zbigniew, Miki, Haruka, Sharabi, Andrew, Kupor, Daniel, Rueda, Ricardo, Hollern, Daniel P, Wang, Joseph, Gutkind, J Silvio
Published in Molecular cancer therapeutics (01.04.2022)
Published in Molecular cancer therapeutics (01.04.2022)
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Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor
Burghi, Valeria, Paradis, Justine S., Officer, Adam, Adame Garcia, Sendi, Wu, Xingyu, Matthees, Edda SF, Barsi-Rhyne, Benjamin, Ramms, Dana J., Clubb, Lauren, Acosta, Monica, Tamayo, Pablo, Bouvier, Michel, Inoue, Asuka, von Zastrow, Mark, Hoffmann, Carsten, Gutkind, J Silvio
Published in The Journal of biological chemistry (01.11.2023)
Published in The Journal of biological chemistry (01.11.2023)
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Discovery of Highly Selective Inhibitors of Microtubule-Associated Serine/Threonine Kinase-like (MASTL)
Gallego, Rebecca A., Scales, Stephanie, Toledo, Chad, Auth, Marin, Bernier, Louise, Berry, Madeline, Brun, Sonja, Chung, Loanne, Davis, Carl, Diehl, Wade, Dress, Klaus, Eisele, Koleen, Elleraas, Jeff, Ewanicki, Jason, Fobian, Yvette, Greasley, Samantha, Greenwald, Eric C., Johnson, Ted W., Khamphavong, Penney, Lafontaine, Jennifer, Li, Jian, Linton, Angelica, Maestre, Michael, Miller, Nichol, Murtaza, Anwar, Patman, Ryan L., Quinlan, Casey L., Ramms, Dana J., Richardson, Paul, Sach, Neal, Salomon-Ferrer, Romelia, Silva, Francisco, Timofeevski, Sergei, Tran, Phuong, Tran-Dubé, Michelle, Wang, Fen, Wang, Wei, Wythes, Martin, Yang, Shouliang, Zou, Aihua, VanArsdale, Todd, McAlpine, Indrawan
Published in Journal of medicinal chemistry (14.11.2024)
Published in Journal of medicinal chemistry (14.11.2024)
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Journal Article
Interpretation of cancer mutations using a multiscale map of protein systems
Zheng, Fan, Kelly, Marcus R, Ramms, Dana J, Heintschel, Marissa L, Tao, Kai, Tutuncuoglu, Beril, Lee, John J, Ono, Keiichiro, Foussard, Helene, Chen, Michael, Herrington, Kari A, Silva, Erica, Liu, Sophie N, Chen, Jing, Churas, Christopher, Wilson, Nicholas, Kratz, Anton, Pillich, Rudolf T, Patel, Devin N, Park, Jisoo, Kuenzi, Brent, Yu, Michael K, Licon, Katherine, Pratt, Dexter, Kreisberg, Jason F, Kim, Minkyu, Swaney, Danielle L, Nan, Xiaolin, Fraley, Stephanie I, Gutkind, J Silvio, Krogan, Nevan J, Ideker, Trey
Published in Science (American Association for the Advancement of Science) (01.10.2021)
Published in Science (American Association for the Advancement of Science) (01.10.2021)
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Journal Article
Interpretation of cancer mutations using a multi-scale map of protein systems
Zheng, Fan, Kelly, Marcus R., Ramms, Dana J., Heintschel, Marissa L., Tao, Kai, Tutuncuoglu, Beril, Lee, John J., Ono, Keiichiro, Foussard, Helene, Chen, Michael, Herrington, Kari A., Silva, Erica, Liu, Sophie, Chen, Jing, Churas, Christopher, Wilson, Nicholas, Kratz, Anton, Pillich, Rudolf T., Patel, Devin N., Park, Jisoo, Kuenzi, Brent, Yu, Michael K., Licon, Katherine, Pratt, Dexter, Kreisberg, Jason F., Kim, Minkyu, Swaney, Danielle L., Nan, Xiaolin, Fraley, Stephanie I., Gutkind, J. Silvio, Krogan, Nevan J., Ideker, Trey
Published in Science (American Association for the Advancement of Science) (01.10.2021)
Published in Science (American Association for the Advancement of Science) (01.10.2021)
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Abstract 5903: MASTL small-molecule inhibition to target mitosis for cancer therapy
Toledo, Chad M., Eisele, Koleen J., Kim, Dong Hyun, Mu, Xinmeng, Brun, Sonja, Davis, Carl, Greenwald, Eric C., Hui, Fion, He, Meilan, Yang, Yanling, Flores-Bojorquez, Ana, Li, Yuxin, Khamphavong, Penney L., Lee, Joseph H., Li, Jian, Ramms, Dana J., Jones, Greg, Auth, Marin, Painter, Cory L., Nager, Andrew, Oyer, Jon, Timofeevski, Sergei L., Pierceall, William E., Murtaza, Anwar, Heyen, Jonathan R., Gallego, Rebecca, Quinlan, Casey, McAlpine, Indrawan, VanArsdale, Todd L.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAF V600E colorectal tumors
Ruiz-Saenz, Ana, Atreya, Chloe E, Wang, Changjun, Pan, Bo, Dreyer, Courtney A, Brunen, Diede, Prahallad, Anirudh, Muñoz, Denise P, Ramms, Dana J, Burghi, Valeria, Spassov, Danislav S, Fewings, Eleanor, Hwang, Yeonjoo C, Cowdrey, Cynthia, Moelders, Christina, Schwarzer, Cecilia, Wolf, Denise M, Hann, Byron, VandenBerg, Scott R, Shokat, Kevan, Moasser, Mark M, Bernards, René, Gutkind, J Silvio, van 't Veer, Laura J, Coppé, Jean-Philippe
Published in Nature cancer (01.02.2023)
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Published in Nature cancer (01.02.2023)
Journal Article
A reversible SRC-relayed COX2-inflammatory program drives therapeutic resistance in BRAF(V600E) colorectal tumors
Ruiz-Saenz, Ana, Atreya, Chloe E, Wang, Changjun, Pan, Bo, Dreyer, Courtney A, Diede Brunen, Prahallad, Anirudh, Munoz, Denise P, Ramms, Dana J, Burghi, Valeria, Spassov, Danislav S, Fewings, Eleanor, Hwang, Yeonjoo C, Cowdrey, Cynthia, Moelders, Christina, Schwarzer, Cecilia, Wolf, Denise M, Hann, Byron, Vandenberg, Scott R, Shokat, Kevan, Moasser, Mark M, Bernards, Rene, J Silvio Gutkind, Van't Veer, Laura J, Coppe, Jean-Philippe
Published in bioRxiv (21.10.2022)
Published in bioRxiv (21.10.2022)
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