Targeting microRNAs in cancer: rationale, strategies and challenges
Garzon, Ramiro, Croce, Carlo M, Marcucci, Guido
Published in Nature reviews. Drug discovery (01.10.2010)
Published in Nature reviews. Drug discovery (01.10.2010)
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CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia
Chen, Ye, Jacamo, Rodrigo, Konopleva, Marina, Garzon, Ramiro, Croce, Carlo, Andreeff, Michael
Published in The Journal of clinical investigation (01.06.2013)
Published in The Journal of clinical investigation (01.06.2013)
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Non-Coding RNAs Are Implicit in Chronic Myeloid Leukemia Therapy Resistance
Rudich, Alexander, Garzon, Ramiro, Dorrance, Adrienne
Published in International journal of molecular sciences (14.10.2022)
Published in International journal of molecular sciences (14.10.2022)
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Journal Article
Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells
Bill, Marius, Papaioannou, Dimitrios, Karunasiri, Malith, Kohlschmidt, Jessica, Pepe, Felice, Walker, Christopher J., Walker, Allison E., Brannan, Zachary, Pathmanathan, Aparna, Zhang, Xiaoli, Mrózek, Krzysztof, LaRocco, Allison, Volinia, Stefano, Bloomfield, Clara D., Garzon, Ramiro, Dorrance, Adrienne M.
Published in Leukemia (01.09.2019)
Published in Leukemia (01.09.2019)
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The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia
Papaioannou, Dimitrios, Petri, Andreas, Dovey, Oliver M., Terreri, Sara, Wang, Eric, Collins, Frances A., Woodward, Lauren A., Walker, Allison E., Nicolet, Deedra, Pepe, Felice, Kumchala, Prasanthi, Bill, Marius, Walker, Christopher J., Karunasiri, Malith, Mrózek, Krzysztof, Gardner, Miranda L., Camilotto, Virginia, Zitzer, Nina, Cooper, Jonathan L., Cai, Xiongwei, Rong-Mullins, Xiaoqing, Kohlschmidt, Jessica, Archer, Kellie J., Freitas, Michael A., Zheng, Yi, Lee, Robert J., Aifantis, Iannis, Vassiliou, George, Singh, Guramrit, Kauppinen, Sakari, Bloomfield, Clara D., Dorrance, Adrienne M., Garzon, Ramiro
Published in Nature communications (25.11.2019)
Published in Nature communications (25.11.2019)
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Journal Article
Expression and prognostic impact of lncRNAs in acute myeloid leukemia
Garzon, Ramiro, Volinia, Stefano, Papaioannou, Dimitrios, Nicolet, Deedra, Kohlschmidt, Jessica, Yan, Pearlly S, Mrózek, Krzysztof, Bucci, Donna, Carroll, Andrew J, Baer, Maria R, Wetzler, Meir, Carter, Thomas H, Powell, Bayard L, Kolitz, Jonathan E, Moore, Joseph O, Eisfeld, Ann-Kathrin, Blachly, James S, Blum, William, Caligiuri, Michael A, Stone, Richard M, Marcucci, Guido, Croce, Carlo M, Byrd, John C, Bloomfield, Clara D
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2014)
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Journal Article
Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia
Ranganathan, Parvathi, Yu, Xueyan, Na, Caroline, Santhanam, Ramasamy, Shacham, Sharon, Kauffman, Michael, Walker, Alison, Klisovic, Rebecca, Blum, William, Caligiuri, Michael, Croce, Carlo M., Marcucci, Guido, Garzon, Ramiro
Published in Blood (30.08.2012)
Published in Blood (30.08.2012)
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Journal Article
Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation
Li, Zhaoyong, Hassan, Mohammad Q., Jafferji, Mohammed, Aqeilan, Rami I., Garzon, Ramiro, Croce, Carlo M., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Published in The Journal of biological chemistry (05.06.2009)
Published in The Journal of biological chemistry (05.06.2009)
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Journal Article
MicroRNA 29b functions in acute myeloid leukemia
Garzon, Ramiro, Heaphy, Catherine E.A., Havelange, Violaine, Fabbri, Muller, Volinia, Stefano, Tsao, Twee, Zanesi, Nicola, Kornblau, Steven M., Marcucci, Guido, Calin, George A., Andreeff, Michael, Croce, Carlo M.
Published in Blood (17.12.2009)
Published in Blood (17.12.2009)
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Journal Article
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
Fabbri, Muller, Garzon, Ramiro, Cimmino, Amelia, Liu, Zhongfa, Zanesi, Nicola, Callegari, Elisa, Liu, Shujun, Alder, Hansjuerg, Costinean, Stefan, Fernandez-Cymering, Cecilia, Volinia, Stefano, Guler, Gulnur, Morrison, Carl D, Chan, Kenneth K, Marcucci, Guido, Calin, George A, Huebner, Kay, Croce, Carlo M
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2007)
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Journal Article
A MicroRNA Signature of Hypoxia
Kulshreshtha, Ritu, Ferracin, Manuela, Wojcik, Sylwia E., Garzon, Ramiro, Alder, Hansjuerg, Agosto-Perez, Francisco J., Davuluri, Ramana, Liu, Chang-Gong, Croce, Carlo M., Negrini, Massimo, Calin, George A., Ivan, Mircea
Published in Molecular and Cellular Biology (01.03.2007)
Published in Molecular and Cellular Biology (01.03.2007)
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Journal Article
Knockout of both miR-15/16 loci induces acute myeloid leukemia
Lovat, Francesca, Fassan, Matteo, Sacchi, Diana, Ranganathan, Parvathi, Palamarchuk, Alexey, Bill, Marius, Karunasiri, Malith, Gasparini, Pierluigi, Nigita, Giovanni, Distefano, Rosario, Veneziano, Dario, Dorrance, Adrienne M., Garzon, Ramiro, Croce, Carlo M.
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2018)
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Journal Article
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
Garzon, Ramiro, Liu, Shujun, Fabbri, Muller, Liu, Zhongfa, Heaphy, Catherine E.A., Callegari, Elisa, Schwind, Sebastian, Pang, Jiuxia, Yu, Jianhua, Muthusamy, Natarajan, Havelange, Violaine, Volinia, Stefano, Blum, William, Rush, Laura J., Perrotti, Danilo, Andreeff, Michael, Bloomfield, Clara D., Byrd, John C., Chan, Kenneth, Wu, Lai-Chu, Croce, Carlo M., Marcucci, Guido
Published in Blood (18.06.2009)
Published in Blood (18.06.2009)
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Journal Article
Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia
XIAOMENG HUANG, SCHWIND, Sebastian, BLUM, William, PERROTTI, Danilo, BYRD, John C, BLOOMFIELD, Clara D, CALIGIURI, Michael A, LEE, Robert J, GARZON, Ramiro, MUTHUSAMY, Natarajan, LEE, Ly James, MARCUCCI, Guido, BO YU, SANTHANAM, Ramasamy, HONGYAN WANG, HOELLERBAUER, Pia, MIMS, Alice, KLISOVIC, Rebecca, WALKER, Alison R, CHAN, Kenneth K
Published in Clinical cancer research (01.05.2013)
Published in Clinical cancer research (01.05.2013)
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Journal Article
MiR-15a and miR-16-1 cluster functions in human leukemia
Calin, George A, Cimmino, Amelia, Fabbri, Muller, Ferracin, Manuela, Wojcik, Sylwia E, Shimizu, Masayoshi, Taccioli, Cristian, Zanesi, Nicola, Garzon, Ramiro, Aqeilan, Rami I, Alder, Hansjuerg, Volinia, Stefano, Rassenti, Laura, Liu, Xiuping, Liu, Chang-gong, Kipps, Thomas J, Negrini, Massimo, Croce, Carlo M
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.2008)
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Journal Article
miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts
Eiring, Anna M., Harb, Jason G., Neviani, Paolo, Garton, Christopher, Oaks, Joshua J., Spizzo, Riccardo, Liu, Shujun, Schwind, Sebastian, Santhanam, Ramasamy, Hickey, Christopher J., Becker, Heiko, Chandler, Jason C., Andino, Raul, Cortes, Jorge, Hokland, Peter, Huettner, Claudia S., Bhatia, Ravi, Roy, Denis C., Liebhaber, Stephen A., Caligiuri, Michael A., Marcucci, Guido, Garzon, Ramiro, Croce, Carlo M., Calin, George A., Perrotti, Danilo
Published in Cell (05.03.2010)
Published in Cell (05.03.2010)
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Journal Article
MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis
Pichiorri, Flavia, Suh, Sung-Suk, Ladetto, Marco, Kuehl, Michael, Palumbo, Tiziana, Drandi, Daniela, Taccioli, Cristian, Zanesi, Nicola, Alder, Hansjuerg, Hagan, John P, Munker, Reinhold, Volinia, Stefano, Boccadoro, Mario, Garzon, Ramiro, Palumbo, Antonio, Aqeilan, Rami I, Croce, Carlo M
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2008)
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