Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor
Thomson, Douglas W, Poeckel, Daniel, Zinn, Nico, Rau, Christina, Strohmer, Katrin, Wagner, Anne J, Graves, Alan P, Perrin, Jessica, Bantscheff, Marcus, Duempelfeld, Birgit, Kasparcova, Viera, Ramanjulu, Joshi M, Pesiridis, G. Scott, Muelbaier, Marcel, Bergamini, Giovanna
Published in ACS medicinal chemistry letters (09.05.2019)
Published in ACS medicinal chemistry letters (09.05.2019)
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Journal Article
Design of amidobenzimidazole STING receptor agonists with systemic activity
Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John
Published in Nature (London) (01.12.2018)
Published in Nature (London) (01.12.2018)
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Journal Article
A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection
Sze-Ling, Ng, Maehr, Rene, Morales, Angel, Ramanjulu, Joshi M
Published in Science Immunology (18.05.2021)
Published in Science Immunology (18.05.2021)
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Journal Article
Web Resource
STING Agonist Induced Innate Immune Responses Drive Anti-Respiratory Virus Activity In Vitro with Limited Antiviral Efficacy In Vivo
Broeckel, Rebecca, Browne, Amanda, Sucoloski, Scott, Cantizani, Juan, Simpson, Juliet. K., Pesiridis, Scott, Ramanjulu, Joshi M., Stokes, Neil, Luthra, Priya
Published in ACS infectious diseases (13.09.2024)
Published in ACS infectious diseases (13.09.2024)
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Journal Article
Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction
Ramanjulu, Joshi M, Williams, Shawn P, Lakdawala, Ami S, DeMartino, Michael P, Lan, Yunfeng, Marquis, Robert W
Published in ACS medicinal chemistry letters (09.09.2021)
Published in ACS medicinal chemistry letters (09.09.2021)
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Journal Article
Titanium(IV) Isopropoxide Mediated Synthesis of Pyrimidin-4-ones
Ramanjulu, Joshi M, DeMartino, Michael P, Lan, Yunfeng, Marquis, Robert
Published in Organic letters (21.05.2010)
Published in Organic letters (21.05.2010)
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Journal Article
Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity
Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John
Published in Nature (London) (01.06.2019)
Published in Nature (London) (01.06.2019)
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Journal Article
Total Synthesis of Vancomycin-Part 1: Design and Development of Methodology
Nicolaou, K. C., Li, Hui, Boddy, Christopher N. C., Ramanjulu, Joshi M., Yue, Tai-Yuen, Natarajan, Swaminathan, Chu, Xin-Jie, Bräse, Stefan, Rübsam, Frank
Published in Chemistry : a European journal (03.09.1999)
Published in Chemistry : a European journal (03.09.1999)
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Journal Article
Total Synthesis of Vancomycin Aglycon-Part 1: Synthesis of Amino Acids 4-7 and Construction of the AB-COD Ring Skeleton
Nicolaou, K. C., Natarajan, Swaminathan, Li, Hui, Jain, Nareshkumar F., Hughes, Robert, Solomon, Michael E., Ramanjulu, Joshi M., Boddy, Christopher N. C., Takayanagi, Masaru
Published in Angewandte Chemie International Edition (16.10.1998)
Published in Angewandte Chemie International Edition (16.10.1998)
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Journal Article
Total Synthesis of Vancomycin-Part 2: Retrosynthetic Analysis, Synthesis of Amino Acid Building Blocks and Strategy Evaluations
Nicolaou, K. C., Boddy, Christopher N. C., Li, Hui, Koumbis, Alexandros E., Hughes, Robert, Natarajan, Swaminathan, Jain, Nareshkumar F., Ramanjulu, Joshi M., Bräse, Stefan, Solomon, Michael E.
Published in Chemistry : a European journal (03.09.1999)
Published in Chemistry : a European journal (03.09.1999)
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Journal Article
Total Synthesis of Vancomycin Aglycon-Part 2: Synthesis of Amino Acids 1-3 and Construction of the AB-COD-DOE Ring Skeleton
Nicolaou, K. C., Jain, Nareshkumar F., Natarajan, Swaminathan, Hughes, Robert, Solomon, Michael E., Li, Hui, Ramanjulu, Joshi M., Takayanagi, Masaru, Koumbis, Alexandros E., Bando, Toshikazu
Published in Angewandte Chemie International Edition (16.10.1998)
Published in Angewandte Chemie International Edition (16.10.1998)
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Journal Article
단백질 조절제로서 유용한 헤테로사이클릭 아미드
LI YUE, DODSON JASON W, RAMANJULU JOSHI M, CHARNLEY ADAM KENNETH, HUGHES TERRY V, NEVINS NEYSA, DARCY MICHAEL G, LIAN YIQIAN
Year of Publication 12.12.2018
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Year of Publication 12.12.2018
Patent
HETEROCYCLIC AMIDES AS KINASE INHIBITORS
RAMANJULU JOSHI M, HARRIS PHILIP ANTHONY, SEHON CLARK A, KANG JIANXING, BANDYOPADHYAY DEEPAK, GOUGH PETER J, KING BRYAN WAYNE, LEISTER LARA KATHRYN, SINGHAUS JR. ROBERT, EIDAM PATRICK M, RAHMAN ATTIQ, LAKDAWALA SHAH AMI, ZHANG DAOHUA, JEONG JAE U, MARQUIS JR. ROBERT W
Year of Publication 22.02.2019
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Year of Publication 22.02.2019
Patent
Inhibition of Protein Synthesis by Didemnins: Cell Potency and SAR
Ahuja, Deepika, Geiger, Adam, Ramanjulu, Joshi M, Vera, Matthew D, SirDeshpande, Bhagyashri, Pfizenmayer, Amy, Abazeed, Mohamed, Krosky, Daniel J, Beidler, David, Joullié, Madeleine M, Toogood, Peter L
Published in Journal of medicinal chemistry (02.11.2000)
Published in Journal of medicinal chemistry (02.11.2000)
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단백질 조정제로서 유용한 헤테로시클릭 아미드
LI YUE, RAMANJULU JOSHI M, CHARNLEY ADAM KENNETH, MEHLMANN JOHN F, HUGHES TERRY V, YE GUOSEN, KANG JIANXING, DARCY MICHAEL G, LEISTER LARA KATHRYN, DODSON JASON W, DONG XIAOYANG, ZHANG DAOHUA, NEVINS NEYSA, LIAN YIQIAN, ROMANO JOSEPH J, WANG GREN Z
Year of Publication 12.12.2018
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Year of Publication 12.12.2018
Patent
HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS
LI YUE, RAMANJULU JOSHI M, CHARNLEY ADAM KENNETH, MEHLMANN JOHN F, HUGHES TERRY V, YE GUOSEN, KANG JIANXING, DARCY MICHAEL G, LEISTER LARA KATHRYN, DODSON JASON W, DONG XIAOYANG, ZHANG DAOHUA, NEVINS NEYSA, LIAN YIQIAN, ROMANO JOSEPH J, WANG GREN Z
Year of Publication 20.11.2018
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Year of Publication 20.11.2018
Patent
AMINO-QUINOLINES AS KINASE INHIBITORS
CASILLAS LINDA N, RAMANJULU JOSHI M, MEHLMANN JOHN F, DEMARTINO MICHAEL P, SINGHAUS ROBERT JR, HAILE PAMELA A
Year of Publication 19.05.2015
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Year of Publication 19.05.2015
Patent
Synthesis of a Reduced Ring Analog of Didemnin B
Ramanjulu, Joshi M, Ding, Xiaobin, Joullié, Madeleine M, Li, Wen-Ren
Published in Journal of organic chemistry (25.07.1997)
Published in Journal of organic chemistry (25.07.1997)
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