Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids
Obeng, Samuel, Kamble, Shyam H, Reeves, Morgan E, Restrepo, Luis F, Patel, Avi, Behnke, Mira, Chear, Nelson J.-Y, Ramanathan, Surash, Sharma, Abhisheak, León, Francisco, Hiranita, Takato, Avery, Bonnie A, McMahon, Lance R, McCurdy, Christopher R
Published in Journal of medicinal chemistry (09.01.2020)
Published in Journal of medicinal chemistry (09.01.2020)
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Journal Article
Accelerated Solvent Extractions (ASE) of Mitragyna speciosa Korth. (Kratom) Leaves: Evaluation of Its Cytotoxicity and Antinociceptive Activity
Goh, Yong Sean, Karunakaran, Thiruventhan, Murugaiyah, Vikneswaran, Santhanam, Rameshkumar, Abu Bakar, Mohamad Hafizi, Ramanathan, Surash
Published in Molecules (Basel, Switzerland) (17.06.2021)
Published in Molecules (Basel, Switzerland) (17.06.2021)
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Journal Article
Comparative Toxicity Assessment of Kratom Decoction, Mitragynine and Speciociliatine Versus Morphine on Zebrafish (Danio rerio) Embryos
Damodaran, Thenmoly, Chear, Nelson Jeng-Yeou, Murugaiyah, Vikneswaran, Mordi, Mohd Nizam, Ramanathan, Surash
Published in Frontiers in pharmacology (20.08.2021)
Published in Frontiers in pharmacology (20.08.2021)
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Journal Article
Mitragynine (Kratom) impairs spatial learning and hippocampal synaptic transmission in rats
Hassan, Zurina, Suhaimi, Farah W, Ramanathan, Surash, Ling, King-Hwa, Effendy, Mohamad A, Müller, Christian P, Dringenberg, Hans C
Published in Journal of psychopharmacology (Oxford) (01.07.2019)
Published in Journal of psychopharmacology (Oxford) (01.07.2019)
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Journal Article
Understanding the physicochemical properties of mitragynine, a principal alkaloid of Mitragyna speciosa, for preclinical evaluation
Ramanathan, Surash, Parthasarathy, Suhanya, Murugaiyah, Vikneswaran, Magosso, Enrico, Tan, Soo Choon, Mansor, Sharif Mahsufi
Published in Molecules (Basel, Switzerland) (18.03.2015)
Published in Molecules (Basel, Switzerland) (18.03.2015)
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Journal Article
Chitosan-Based Nanoencapsulated Essential Oils: Potential Leads against Breast Cancer Cells in Preclinical Studies
Tan, Wen-Nee, Samling, Benedict Anak, Tong, Woei-Yenn, Chear, Nelson Jeng-Yeou, Yusof, Siti R, Lim, Jun-Wei, Tchamgoue, Joseph, Leong, Chean-Ring, Ramanathan, Surash
Published in Polymers (01.02.2024)
Published in Polymers (01.02.2024)
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Journal Article
In Vitro antioxidant and xanthine oxidase inhibitory activities of methanolic Swietenia mahagoni seed extracts
Sahgal, Geethaa, Ramanathan, Surash, Sasidharan, Sreenivasan, Mordi, Mohd Nizam, Ismail, Sabariah, Mansor, Sharif Mahsufi
Published in Molecules (Basel, Switzerland) (06.11.2009)
Published in Molecules (Basel, Switzerland) (06.11.2009)
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Journal Article
Evaluation of antioxidant and antibacterial activities of aqueous, methanolic and alkaloid extracts from Mitragyna speciosa (Rubiaceae family) leaves
Parthasarathy, Suhanya, Bin Azizi, Juzaili, Ramanathan, Surash, Ismail, Sabariah, Sasidharan, Sreenivasan, Said, Mohd I Mohd, Mansor, Sharif Mahsufi
Published in Molecules (Basel, Switzerland) (09.10.2009)
Published in Molecules (Basel, Switzerland) (09.10.2009)
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Journal Article
RP-HPLC-DAD Analysis of Mitragynine Content in Mitragyna speciosa Korth. (Ketum) Leaf Extracts Prepared Using Ultrasound Assisted Extraction Technique and Their Cytotoxicity
Karunakaran, Thiruventhan, Goh, Yong Sean, Santhanam, Rameshkumar, Murugaiyah, Vikneswaran, Abu Bakar, Mohamad Hafizi, Ramanathan, Surash
Published in Separations (01.11.2022)
Published in Separations (01.11.2022)
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Journal Article
Evaluation of the antinociceptive activity and acute oral toxicity of standardized ethanolic extract of the rhizome of Curcuma xanthorrhiza Roxb
Devaraj, Sutha, Esfahani, Azadeh Sabetghadam, Ismail, Sabariah, Ramanathan, Surash, Yam, Mun Fei
Published in Molecules (Basel, Switzerland) (22.04.2010)
Published in Molecules (Basel, Switzerland) (22.04.2010)
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Journal Article
Natural Corynanthe-Type Cholinesterase Inhibitors from Malaysian Uncaria attenuata Korth.: Isolation, Characterization, In Vitro and In Silico Studies
Chear, Nelson Jeng-Yeou, Ching-Ga, Tan Ai Fein, Khaw, Kooi-Yeong, León, Francisco, Tan, Wen-Nee, Yusof, Siti R, McCurdy, Christopher R, Murugaiyah, Vikneswaran, Ramanathan, Surash
Published in Metabolites (07.03.2023)
Published in Metabolites (07.03.2023)
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Journal Article
In vitro and in vivo effects of three different Mitragyna speciosa korth leaf extracts on phase II drug metabolizing enzymes--glutathione transferases (GSTs)
Azizi, Juzaili, Ismail, Sabariah, Mordi, Mohd Nizam, Ramanathan, Surash, Said, Mohd Ikram Mohd, Mansor, Sharif Mahsufi
Published in Molecules (Basel, Switzerland) (01.01.2010)
Published in Molecules (Basel, Switzerland) (01.01.2010)
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Journal Article
A comparative study on the antioxidant activity of methanolic leaf extracts of Ficus religiosa L, Chromolaena odorata (L.) King & Rabinson, Cynodon dactylon (L.) Pers. and Tridax procumbens L
Melinda, Krishanti P, Rathinam, Xavier, Marimuthu, Kasi, Diwakar, Ayyalu, Ramanathan, Surash, Kathiresan, Sadasivam, Subramaniam, Sreeramanan
Published in Asian Pacific journal of tropical medicine (01.05.2010)
Published in Asian Pacific journal of tropical medicine (01.05.2010)
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Journal Article