Defining the next generation of severe malaria treatment: a target product profile
Achan, Jane, Barry, Aïssata, Leroy, Didier, Kamara, George, Duparc, Stephan, Kaszubska, Wiweka, Gandhi, Preetam, Buffet, Bénédicte, Tshilab, Patrick, Ogutu, Bernhards, Taylor, Terrie, Krishna, Sanjeev, Richardson, Naomi, Ramachandruni, Hanu, Rietveld, Hans
Published in Malaria journal (05.06.2024)
Published in Malaria journal (05.06.2024)
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Journal Article
Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy
Ristroph, Kurt D, Feng, Jie, McManus, Simon A, Zhang, Yingyue, Gong, Kai, Ramachandruni, Hanu, White, Claire E, Prud'homme, Robert K
Published in Journal of translational medicine (22.03.2019)
Published in Journal of translational medicine (22.03.2019)
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Journal Article
Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria
Macintyre, Fiona, Ramachandruni, Hanu, Burrows, Jeremy N, Holm, René, Thomas, Anna, Möhrle, Jörg J, Duparc, Stephan, Hooft van Huijsduijnen, Rob, Greenwood, Brian, Gutteridge, Winston E, Wells, Timothy N C, Kaszubska, Wiweka
Published in Malaria journal (01.11.2018)
Published in Malaria journal (01.11.2018)
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Journal Article
Partnering to fight malaria in India: Past, present and future
Samby, Kirandeep, Ramachandruni, Hanu, Banerji, Jaya, Burrows, Jeremy, Daumerie, Penny, Hooft van Huijsduijnen, Rob, Duparc, Stephan, Wells, Timothy
Published in Journal of vector borne diseases (01.01.2019)
Published in Journal of vector borne diseases (01.01.2019)
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Journal Article
Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria
Salim, Malinda, Khan, Jamal, Ramirez, Gisela, Murshed, Mubtasim, Clulow, Andrew J, Hawley, Adrian, Ramachandruni, Hanu, Beilles, Stephane, Boyd, Ben J
Published in Molecular pharmaceutics (01.04.2019)
Published in Molecular pharmaceutics (01.04.2019)
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Journal Article
Lipid Compositions in Infant Formulas Affect the Solubilization of Antimalarial Drugs Artefenomel (OZ439) and Ferroquine during Digestion
Salim, Malinda, Ramirez, Gisela, Peng, Kang-Yu, Clulow, Andrew J, Hawley, Adrian, Ramachandruni, Hanu, Beilles, Stephane, Boyd, Ben J
Published in Molecular pharmaceutics (06.07.2020)
Published in Molecular pharmaceutics (06.07.2020)
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Journal Article
Amorphous nanoparticles by self-assembly: processing for controlled release of hydrophobic molecules
Feng, Jie, Zhang, Yingyue, McManus, Simon A, Qian, Rolane, Ristroph, Kurt D, Ramachandruni, Hanu, Gong, Kai, White, Claire E, Rawal, Aditya, Prud'homme, Robert K
Published in Soft matter (13.03.2019)
Published in Soft matter (13.03.2019)
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Journal Article
Interactions of Artefenomel (OZ439) with Milk during Digestion: Insights into Digestion-Driven Solubilization and Polymorphic Transformations
Salim, Malinda, Khan, Jamal, Ramirez, Gisela, Clulow, Andrew J, Hawley, Adrian, Ramachandruni, Hanu, Boyd, Ben J
Published in Molecular pharmaceutics (06.08.2018)
Published in Molecular pharmaceutics (06.08.2018)
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A randomized, open-label two-period crossover pilot study to evaluate the relative bioavailability in the fed state of atovaquone-proguanil (Atoguanil™) versus atovaquone-proguanil hydrochloride (Malarone®) in healthy adult participants
Kuemmerle, Andrea, Gossen, Denis, Marx, Michael W., Lorch, Ulrike, Szramowska, Maja, Kumar, Ashok, Singh, Dharmendra, Singh, Satinder, Ramachandruni, Hanu, Thankachen, Byju, Kore, Swapnil, Gaaloul, Myriam El, Borghini-Fuhrer, Isabelle, Chalon, Stephan
Published in Naunyn-Schmiedeberg's archives of pharmacology (25.06.2024)
Published in Naunyn-Schmiedeberg's archives of pharmacology (25.06.2024)
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Journal Article
Encapsulation of OZ439 into Nanoparticles for Supersaturated Drug Release in Oral Malaria Therapy
Lu, Hoang D., Ristroph, Kurt D., Dobrijevic, Ellen L. K., Feng, Jie, McManus, Simon A., Zhang, Yingyue, Mulhearn, William D., Ramachandruni, Hanu, Patel, Anil, Prud’homme, Robert K.
Published in ACS infectious diseases (08.06.2018)
Published in ACS infectious diseases (08.06.2018)
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Journal Article
Effect of High Shear Blending Protocols and Blender Parameters on the Degree of API Agglomeration in Solid Formulations
Llusa, Marcos, Sturm, Kurt, Sudah, Osama, Stamato, Howard, Goldfarb, David J, Ramachandruni, Hanu, Hammond, Steve, Smith, Mark R, Muzzio, Fernando J
Published in Industrial & engineering chemistry research (07.01.2009)
Published in Industrial & engineering chemistry research (07.01.2009)
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Journal Article
A Prodrug Strategy to Reposition Atovaquone as a Long-Acting Injectable for Malaria Chemoprotection
Gupta, Anil K, Eliasen, Anders M, Andahazy, Wil, Zhou, Fei, Henson, Kerstin, Chi, Victor, Woods, Ashley K, Joseph, Sean B, Kuhen, Kelli L, Wisler, John, Ramachandruni, Hanu, Duffy, James, Burrows, Jeremy N, Vadas, Elizabeth, Slade, Andrew, Schultz, Peter G, McNamara, Case W, Chatterjee, Arnab K
Published in bioRxiv (25.06.2024)
Published in bioRxiv (25.06.2024)
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