Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
Yang, Lifeng, Achreja, Abhinav, Yeung, Tsz-Lun, Mangala, Lingegowda S., Jiang, Dahai, Han, Cecil, Baddour, Joelle, Marini, Juan C., Ni, Joseph, Nakahara, Ryuichi, Wahlig, Stephen, Chiba, Lisa, Kim, Sun Hye, Morse, Joshua, Pradeep, Sunila, Nagaraja, Archana Sidalaghatta, Haemmerle, Monika, Kyunghee, Noh, Derichsweiler, Mathew, Plackemeier, Thomas, Mercado-Uribe, Imelda, Lopez-Berestein, Gabriel, Moss, Tyler, Ram, Prahlad T., Liu, Jinsong, Lu, Xiongbin, Mok, Samuel C., Sood, Anil K., Nagrath, Deepak
Published in Cell metabolism (08.11.2016)
Published in Cell metabolism (08.11.2016)
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Journal Article
Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
Zhao, Hongyun, Yang, Lifeng, Baddour, Joelle, Achreja, Abhinav, Bernard, Vincent, Moss, Tyler, Marini, Juan C, Tudawe, Thavisha, Seviour, Elena G, San Lucas, F Anthony, Alvarez, Hector, Gupta, Sonal, Maiti, Sourindra N, Cooper, Laurence, Peehl, Donna, Ram, Prahlad T, Maitra, Anirban, Nagrath, Deepak
Published in eLife (27.02.2016)
Published in eLife (27.02.2016)
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Journal Article
A pan-cancer proteomic perspective on The Cancer Genome Atlas
Akbani, Rehan, Ng, Patrick Kwok Shing, Werner, Henrica M. J., Shahmoradgoli, Maria, Zhang, Fan, Ju, Zhenlin, Liu, Wenbin, Yang, Ji-Yeon, Yoshihara, Kosuke, Li, Jun, Ling, Shiyun, Seviour, Elena G., Ram, Prahlad T., Minna, John D., Diao, Lixia, Tong, Pan, Heymach, John V., Hill, Steven M., Dondelinger, Frank, Städler, Nicolas, Byers, Lauren A., Meric-Bernstam, Funda, Weinstein, John N., Broom, Bradley M., Verhaak, Roeland G. W., Liang, Han, Mukherjee, Sach, Lu, Yiling, Mills, Gordon B.
Published in Nature communications (29.05.2014)
Published in Nature communications (29.05.2014)
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Journal Article
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
Yang, Lifeng, Moss, Tyler, Mangala, Lingegowda S, Marini, Juan, Zhao, Hongyun, Wahlig, Stephen, Armaiz‐Pena, Guillermo, Jiang, Dahai, Achreja, Abhinav, Win, Julia, Roopaimoole, Rajesha, Rodriguez‐Aguayo, Cristian, Mercado‐Uribe, Imelda, Lopez‐Berestein, Gabriel, Liu, Jinsong, Tsukamoto, Takashi, Sood, Anil K., Ram, Prahlad T, Nagrath, Deepak
Published in Molecular systems biology (01.05.2014)
Published in Molecular systems biology (01.05.2014)
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Journal Article
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
Taube, Joseph H., Herschkowitz, Jason I., Komurov, Kakajan, Zhou, Alicia Y., Gupta, Supriya, Yang, Jing, Hartwell, Kimberly, Onder, Tamer T., Gupta, Piyush B., Evans, Kurt W., Hollier, Brett G., Ram, Prahlad T., Lander, Eric S., Rosen, Jeffrey M., Weinberg, Robert A., Mani, Sendurai A.
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2010)
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Journal Article
Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho-Proteomics and Computational Network Analysis
LADEVAIA, Sergio, YILING LU, MORALES, Fabiana C, MILLS, Gordon B, RAM, Prahlad T
Published in Cancer research (Chicago, Ill.) (01.09.2010)
Published in Cancer research (Chicago, Ill.) (01.09.2010)
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Journal Article
NetWalker: a contextual network analysis tool for functional genomics
Komurov, Kakajan, Dursun, Serkan, Erdin, Serkan, Ram, Prahlad T
Published in BMC genomics (25.06.2012)
Published in BMC genomics (25.06.2012)
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Journal Article
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
Mills, Gordon B, Hennessy, Bryan T, Smith, Debra L, Ram, Prahlad T, Lu, Yiling
Published in Nature reviews. Drug discovery (01.12.2005)
Published in Nature reviews. Drug discovery (01.12.2005)
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Journal Article
Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling
Parashar, Deepak, Nair, Bindu, Geethadevi, Anjali, George, Jasmine, Nair, Ajay, Tsaih, Shirng-Wern, Kadamberi, Ishaque P, Gopinadhan Nair, Gopa Kumar, Lu, Yiling, Ramchandran, Ramani, Uyar, Denise S, Rader, Janet S, Ram, Prahlad T, Mills, Gordon B, Pradeep, Sunila, Chaluvally-Raghavan, Pradeep
Published in Cancer research (Chicago, Ill.) (15.12.2020)
Published in Cancer research (Chicago, Ill.) (15.12.2020)
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Journal Article
Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction
Allen, Julie K, Armaiz-Pena, Guillermo N, Nagaraja, Archana S, Sadaoui, Nouara C, Ortiz, Tatiana, Dood, Robert, Ozcan, Merve, Herder, Danielle M, Haemmerle, Monika, Gharpure, Kshipra M, Rupaimoole, Rajesha, Previs, Rebecca A, Wu, Sherry Y, Pradeep, Sunila, Xu, Xiaoyun, Han, Hee Dong, Zand, Behrouz, Dalton, Heather J, Taylor, Morgan, Hu, Wei, Bottsford-Miller, Justin, Moreno-Smith, Myrthala, Kang, Yu, Mangala, Lingegowda S, Rodriguez-Aguayo, Cristian, Sehgal, Vasudha, Spaeth, Erika L, Ram, Prahlad T, Wong, Stephen T C, Marini, Frank C, Lopez-Berestein, Gabriel, Cole, Steve W, Lutgendorf, Susan K, De Biasi, Mariella, Sood, Anil K
Published in Cancer research (Chicago, Ill.) (15.06.2018)
Published in Cancer research (Chicago, Ill.) (15.06.2018)
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A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease
Nishikawa, Taichiro, Bellance, Nadège, Damm, Aaron, Bing, Han, Zhu, Zhen, Handa, Kan, Yovchev, Mladen I, Sehgal, Vasudha, Moss, Tyler J, Oertel, Michael, Ram, Prahlad T, Pipinos, Iraklis I, Soto-Gutierrez, Alejandro, Fox, Ira J, Nagrath, Deepak
Published in Journal of hepatology (01.06.2014)
Published in Journal of hepatology (01.06.2014)
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Journal Article
G Protein Pathways
Neves, Susana R., Ram, Prahlad T., Iyengar, Ravi
Published in Science (American Association for the Advancement of Science) (31.05.2002)
Published in Science (American Association for the Advancement of Science) (31.05.2002)
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Journal Article
Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data
Komurov, Kakajan, White, Michael A, Ram, Prahlad T
Published in PLoS computational biology (01.08.2010)
Published in PLoS computational biology (01.08.2010)
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Journal Article
CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance
Ma, Shaolin, Mangala, Lingegowda S., Hu, Wen, Bayaktar, Emine, Yokoi, Akira, Hu, Wei, Pradeep, Sunila, Lee, Sanghoon, Piehowski, Paul D., Villar-Prados, Alejandro, Wu, Sherry Y., McGuire, Michael H., Lara, Olivia D., Rodriguez-Aguayo, Cristian, LaFargue, Christopher J., Jennings, Nicholas B., Rodland, Karin D., Liu, Tao, Kundra, Vikas, Ram, Prahlad T., Ramakrishnan, Sundaram, Lopez-Berestein, Gabriel, Coleman, Robert L., Sood, Anil K.
Published in Cell reports (Cambridge) (17.08.2021)
Published in Cell reports (Cambridge) (17.08.2021)
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Journal Article
The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells
Komurov, Kakajan, Tseng, Jen‐Te, Muller, Melissa, Seviour, Elena G, Moss, Tyler J, Yang, Lifeng, Nagrath, Deepak, Ram, Prahlad T
Published in Molecular systems biology (2012)
Published in Molecular systems biology (2012)
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Journal Article
The ZNF304-integrin axis protects against anoikis in cancer
Aslan, Burcu, Monroig, Paloma, Hsu, Ming-Chuan, Pena, Guillermo Armaiz, Rodriguez-Aguayo, Cristian, Gonzalez-Villasana, Vianey, Rupaimoole, Rajesha, Nagaraja, Archana Sidalaghatta, Mangala, Selanere, Han, Hee-Dong, Yuca, Erkan, Wu, Sherry Y., Ivan, Cristina, Moss, Tyler J., Ram, Prahlad T., Wang, Huamin, Gol-Chambers, Alexandra, Ozkayar, Ozgur, Kanlikilicer, Pinar, Fuentes-Mattei, Enrique, Kahraman, Nermin, Pradeep, Sunila, Ozpolat, Bulent, Tucker, Susan, Hung, Mien-Chie, Baggerly, Keith, Bartholomeusz, Geoffrey, Calin, George, Sood, Anil K., Lopez-Berestein, Gabriel
Published in Nature communications (17.06.2015)
Published in Nature communications (17.06.2015)
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Journal Article
Formation of Regulatory Patterns During Signal Propagation in a Mammalian Cellular Network
Ma'ayan, Avi, Jenkins, Sherry L, Neves, Susana, Hasseldine, Anthony, Grace, Elizabeth, Dubin-Thaler, Benjamin, Eungdamrong, Narat J, Weng, Gehzi, Ram, Prahlad T, Rice, J. Jeremy, Kershenbaum, Aaron, Stolovitzky, Gustavo A, Blitzer, Robert D, Iyengar, Ravi
Published in Science (American Association for the Advancement of Science) (12.08.2005)
Published in Science (American Association for the Advancement of Science) (12.08.2005)
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Journal Article
Robust Selection Algorithm (RSA) for Multi-Omic Biomarker Discovery; Integration with Functional Network Analysis to Identify miRNA Regulated Pathways in Multiple Cancers
Sehgal, Vasudha, Seviour, Elena G, Moss, Tyler J, Mills, Gordon B, Azencott, Robert, Ram, Prahlad T
Published in PloS one (27.10.2015)
Published in PloS one (27.10.2015)
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