Efficient Industrial Synthesis of the MDM2 Antagonist Idasanutlin via a Cu(I)-catalyzed [3+2] Asymmetric Cycloaddition
Fishlock, Dan, Diodone, Ralph, Hildbrand, Stefan, Kuhn, Bernd, Mössner, Christian, Peters, Carsten, Rege, Pankaj D, Rimmler, Gösta, Schantz, Markus
Published in Chimia (22.08.2018)
Published in Chimia (22.08.2018)
Get full text
Journal Article
An Efficient Process for the Manufacture of Carmegliptin
Abrecht, Stefan, Adam, Jean-Michel, Bromberger, Ulrike, Diodone, Ralph, Fettes, Alec, Fischer, Rolf, Goeckel, Volker, Hildbrand, Stefan, Moine, Gérard, Weber, Martin
Published in Organic process research & development (20.05.2011)
Published in Organic process research & development (20.05.2011)
Get full text
Journal Article
Redox-Switched Bonding of Protons to Ferrocenophanes, Ferrocene Cryptands, and Simple Ferrocene Amines. Correlation of X-ray Structural Data and Cyclic Voltammetry Derived Redox Potentials
Plenio, Herbert, Yang, Jianjun, Diodone, Ralph, Heinze, Juergen
Published in Inorganic chemistry (01.08.1994)
Published in Inorganic chemistry (01.08.1994)
Get full text
Journal Article
Improved Human Bioavailability of Vemurafenib, a Practically Insoluble Drug, Using an Amorphous Polymer-Stabilized Solid Dispersion Prepared by a Solvent-Controlled Coprecipitation Process
Shah, Navnit, Iyer, Raman M., Mair, Hans-Juergen, Choi, Duksoon, Tian, Hung, Diodone, Ralph, Fahnrich, Karsten, Pabst-Ravot, Anni, Tang, Kin, Scheubel, Emmanuel, Grippo, Joseph F., Moreira, Sebastian A., Go, Zenaida, Mouskountakis, James, Louie, Theresa, Ibrahim, Prabha N., Sandhu, Harpreet, Rubia, Linda, Chokshi, Hitesh, Singhal, Dharmendra, Malick, Waseem
Published in Journal of pharmaceutical sciences (01.03.2013)
Published in Journal of pharmaceutical sciences (01.03.2013)
Get full text
Journal Article
Practical Synthesis of MDM2 Antagonist RG7388. Part 2: Development of the Cu(I) Catalyzed [3 + 2] Asymmetric Cycloaddition Process for the Manufacture of Idasanutlin
Rimmler, Gösta, Alker, Andre, Bosco, Marcello, Diodone, Ralph, Fishlock, Dan, Hildbrand, Stefan, Kuhn, Bernd, Moessner, Christian, Peters, Carsten, Rege, Pankaj D, Schantz, Markus
Published in Organic process research & development (16.12.2016)
Published in Organic process research & development (16.12.2016)
Get full text
Journal Article
A Fluorine-Containing Cryptand for the Complexation of Anions and the Utility of 19F NMR Spectroscopy for the Determination of Host-Guest Association
Plenio, Herbert, Diodone, Ralph
Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences (01.07.1995)
Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences (01.07.1995)
Get full text
Journal Article
SOLID FORMS OF PHARMACEUTICALLY ACTIVE COMPOUND
RALPH DIODONE, BHARAT PATEL, URS SCHWITTER, RUDOLF BENZ, JIA ZHONGJIANG, YAN NINGXIN, CHOI DUK SOON
Year of Publication 11.04.2019
Get full text
Year of Publication 11.04.2019
Patent
SOLID FORMS OF PHARMACEUTICALLY ACTIVE SUBSTANCE
RALPH DIODONE, GARY CONARD VISOR, KARSTEN FAEHNRICH, URS SCHWITTER, ZHAO BAOSHU, PRABHA N IBRAHIM, KUANG SHAN-MING
Year of Publication 25.08.2016
Get full text
Year of Publication 25.08.2016
Patent
SOLID FORMS
Hongyan, He, Dott, Pascal Jean Claude, Diodone, Ralph, Siyi, Jiang, Wyttenbach, Nicole, Grassmann, Olaf, Schwitter, Urs
Year of Publication 12.09.2024
Get full text
Year of Publication 12.09.2024
Patent
SOLID FORM OF 5-(3,4-DICHLOROPHENYL)-N-((1R,2R)-2-HYDROXYCYCLOHEXYL)-6-(2,2,2-TRIFLUOROETHOXY)NICOTINAMIDE FOR USE IN TREATING KIDNEY DISEASES
DOTT, Pascal, WHTTENBACH, Nicole, HONGYAN, He, GRASSMANN, Olaf, SCHWITTER, Urs, DIODONE, Ralph, SIYI, Jiang
Year of Publication 17.07.2024
Get full text
Year of Publication 17.07.2024
Patent
SOLID FORM OF 5-(3,4-DICHLOROPHENYL)-N-((1R,2R)-2-HYDROXYCYCLOHEXYL)-6-(2,2,2-TRIFLUOROETHOXY)NICOTINAMIDE FOR USE IN TREATING KIDNEY DISEASES
DOTT, Pascal, WHTTENBACH, Nicole, HONGYAN, He, GRASSMANN, Olaf, SCHWITTER, Urs, DIODONE, Ralph, SIYI, Jiang
Year of Publication 14.03.2024
Get full text
Year of Publication 14.03.2024
Patent