BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files
Payne, Alexander, Holmes, Nadine, Rakyan, Vardhman, Loose, Matthew
Published in Bioinformatics (Oxford, England) (01.07.2019)
Published in Bioinformatics (Oxford, England) (01.07.2019)
Get full text
Journal Article
Epigenome-wide association studies for common human diseases
Rakyan, Vardhman K, Balding, David J, Beck, Stephan, Down, Thomas A
Published in Nature reviews. Genetics (01.08.2011)
Published in Nature reviews. Genetics (01.08.2011)
Get full text
Journal Article
DNA methylation aging clocks: challenges and recommendations
Bell, Christopher G, Lowe, Robert, Adams, Peter D, Baccarelli, Andrea A, Beck, Stephan, Bell, Jordana T, Christensen, Brock C, Gladyshev, Vadim N, Heijmans, Bastiaan T, Horvath, Steve, Ideker, Trey, Issa, Jean-Pierre J, Kelsey, Karl T, Marioni, Riccardo E, Reik, Wolf, Relton, Caroline L, Schalkwyk, Leonard C, Teschendorff, Andrew E, Wagner, Wolfgang, Zhang, Kang, Rakyan, Vardhman K
Published in Genome Biology (25.11.2019)
Published in Genome Biology (25.11.2019)
Get full text
Journal Article
Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring
Finer, Sarah, Mathews, Chris, Lowe, Rob, Smart, Melissa, Hillman, Sara, Foo, Lin, Sinha, Ajay, Williams, David, Rakyan, Vardhman K, Hitman, Graham A
Published in Human molecular genetics (01.06.2015)
Published in Human molecular genetics (01.06.2015)
Get full text
Journal Article
Protection against De Novo Methylation Is Instrumental in Maintaining Parent-of-Origin Methylation Inherited from the Gametes
Proudhon, Charlotte, Duffié, Rachel, Ajjan, Sophie, Cowley, Michael, Iranzo, Julian, Carbajosa, Guillermo, Saadeh, Heba, Holland, Michelle L., Oakey, Rebecca J., Rakyan, Vardhman K., Schulz, Reiner, Bourc’his, Déborah
Published in Molecular cell (28.09.2012)
Published in Molecular cell (28.09.2012)
Get full text
Journal Article
Correlation of an epigenetic mitotic clock with cancer risk
Yang, Zhen, Wong, Andrew, Kuh, Diana, Paul, Dirk S, Rakyan, Vardhman K, Leslie, R David, Zheng, Shijie C, Widschwendter, Martin, Beck, Stephan, Teschendorff, Andrew E
Published in Genome Biology (03.10.2016)
Published in Genome Biology (03.10.2016)
Get full text
Journal Article
Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Thurner, Matthias, van de Bunt, Martijn, Torres, Jason M, Mahajan, Anubha, Nylander, Vibe, Bennett, Amanda J, Gaulton, Kyle J, Barrett, Amy, Burrows, Carla, Bell, Christopher G, Lowe, Robert, Beck, Stephan, Rakyan, Vardhman K, Gloyn, Anna L, McCarthy, Mark I
Published in eLife (07.02.2018)
Published in eLife (07.02.2018)
Get full text
Journal Article
Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis
Rakyan, Vardhman K, Beyan, Huriya, Down, Thomas A, Hawa, Mohammed I, Maslau, Siarhei, Aden, Deeqo, Daunay, Antoine, Busato, Florence, Mein, Charles A, Manfras, Burkhard, Dias, Kerith-Rae M, Bell, Christopher G, Tost, Jörg, Boehm, Bernhard O, Beck, Stephan, Leslie, R David
Published in PLoS genetics (01.09.2011)
Published in PLoS genetics (01.09.2011)
Get full text
Journal Article
Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
Rakyan, Vardhman K, Down, Thomas A, Maslau, Siarhei, Andrew, Toby, Yang, Tsun-Po, Beyan, Huriya, Whittaker, Pamela, McCann, Owen T, Finer, Sarah, Valdes, Ana M, Leslie, R David, Deloukas, Panogiotis, Spector, Timothy D
Published in Genome research (01.04.2010)
Published in Genome research (01.04.2010)
Get full text
Journal Article
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus
Bell, Christopher G, Finer, Sarah, Lindgren, Cecilia M, Wilson, Gareth A, Rakyan, Vardhman K, Teschendorff, Andrew E, Akan, Pelin, Stupka, Elia, Down, Thomas A, Prokopenko, Inga, Morison, Ian M, Mill, Jonathan, Pidsley, Ruth, Deloukas, Panos, Frayling, Timothy M, Hattersley, Andrew T, McCarthy, Mark I, Beck, Stephan, Hitman, Graham A
Published in PloS one (18.11.2010)
Published in PloS one (18.11.2010)
Get full text
Journal Article
The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations
Åsenius, Fredrika, Gorrie-Stone, Tyler J, Brew, Ama, Panchbhaya, Yasmin, Williamson, Elizabeth, Schalkwyk, Leonard C, Rakyan, Vardhman K, Holland, Michelle L, Marzi, Sarah J, Williams, David J
Published in PLoS genetics (13.10.2020)
Published in PLoS genetics (13.10.2020)
Get full text
Journal Article
Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice
Holland, Michelle L., Lowe, Robert, Caton, Paul W., Gemma, Carolina, Carbajosa, Guillermo, Danson, Amy F., Carpenter, Asha A. M., Loche, Elena, Ozanne, Susan E., Rakyan, Vardhman K.
Published in Science (American Association for the Advancement of Science) (29.07.2016)
Published in Science (American Association for the Advancement of Science) (29.07.2016)
Get full text
Journal Article
Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species
Lowe, Robert, Barton, Carl, Jenkins, Christopher A, Ernst, Christina, Forman, Oliver, Fernandez-Twinn, Denise S, Bock, Christoph, Rossiter, Stephen J, Faulkes, Chris G, Ozanne, Susan E, Walter, Lutz, Odom, Duncan T, Mellersh, Cathryn, Rakyan, Vardhman K
Published in Genome Biology (16.02.2018)
Published in Genome Biology (16.02.2018)
Get full text
Journal Article
Author Correction: The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans
Lowe, Robert, Overhoff, Marita G, Ramagopalan, Sreeram V, Garbe, James C, Koh, James, Stampfer, Martha R, Beach, David H, Rakyan, Vardhman K, Bishop, Cleo L
Published in Genome Biology (10.06.2024)
Published in Genome Biology (10.06.2024)
Get full text
Journal Article
Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
Vinel, Claire, Rosser, Gabriel, Guglielmi, Loredana, Constantinou, Myrianni, Pomella, Nicola, Zhang, Xinyu, Boot, James R., Jones, Tania A., Millner, Thomas O., Dumas, Anaelle A., Rakyan, Vardhman, Rees, Jeremy, Thompson, Jamie L., Vuononvirta, Juho, Nadkarni, Suchita, El Assan, Tedani, Aley, Natasha, Lin, Yung-Yao, Liu, Pentao, Nelander, Sven, Sheer, Denise, Merry, Catherine L. R., Marelli-Berg, Federica, Brandner, Sebastian, Marino, Silvia
Published in Nature communications (21.10.2021)
Published in Nature communications (21.10.2021)
Get full text
Journal Article
DNA methylation profiling of human chromosomes 6, 20 and 22
Eckhardt, Florian, Beck, Stephan, Lewin, Joern, Cortese, Rene, Rakyan, Vardhman K, Attwood, John, Burger, Matthias, Burton, John, Cox, Tony V, Davies, Rob, Down, Thomas A, Haefliger, Carolina, Horton, Roger, Howe, Kevin, Jackson, David K, Kunde, Jan, Koenig, Christoph, Liddle, Jennifer, Niblett, David, Otto, Thomas, Pettett, Roger, Seemann, Stefanie, Thompson, Christian, West, Tony, Rogers, Jane, Olek, Alex, Berlin, Kurt
Published in Nature genetics (01.12.2006)
Published in Nature genetics (01.12.2006)
Get full text
Journal Article