Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal
Wierenga, Kathryn A, Wee, Josephine, Gilley, Kristen N, Rajasinghe, Lichchavi D, Bates, Melissa A, Gavrilin, Mikhail A, Holian, Andrij, Pestka, James J
Published in Frontiers in immunology (20.09.2019)
Published in Frontiers in immunology (20.09.2019)
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Journal Article
Crystalline silica-induced proinflammatory eicosanoid storm in novel alveolar macrophage model quelled by docosahexaenoic acid supplementation
Favor, Olivia K, Rajasinghe, Lichchavi D, Wierenga, Kathryn A, Maddipati, Krishna R, Lee, Kin Sing Stephen, Olive, Andrew J, Pestka, James J
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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Journal Article
Subchronic intranasal lipopolysaccharide exposure induces pulmonary autoimmunity and glomerulonephritis in NZBWF1 mice
Heine, Lauren K, Rajasinghe, Lichchavi D, Wagner, James G, Lewandowski, Ryan P, Li, Quan-Zhen, Richardson, Alexa L, Tindle, Ashleigh N, Shareef, Jenan J, Harkema, Jack R, Pestka, James J
Published in Autoimmunity (Chur, Switzerland) (01.12.2024)
Published in Autoimmunity (Chur, Switzerland) (01.12.2024)
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Journal Article
Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice
Rajasinghe, Lichchavi D., Li, Quan-Zhen, Zhu, Chengsong, Yan, Mei, Chauhan, Preeti S., Wierenga, Kathryn A., Bates, Melissa A., Harkema, Jack R., Benninghoff, Abby D., Pestka, James J.
Published in Autoimmunity (Chur, Switzerland) (02.10.2020)
Published in Autoimmunity (Chur, Switzerland) (02.10.2020)
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Journal Article
Dietary docosahexaenoic acid supplementation inhibits acute pulmonary transcriptional and autoantibody responses to a single crystalline silica exposure in lupus-prone mice
Chauhan, Preeti S, Benninghoff, Abby D, Favor, Olivia K, Wagner, James G, Lewandowski, Ryan P, Rajasinghe, Lichchavi D, Li, Quan-Zhen, Harkema, Jack R, Pestka, James J
Published in Frontiers in immunology (01.02.2024)
Published in Frontiers in immunology (01.02.2024)
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Journal Article
Silica Induction of Diverse Inflammatory Proteome in Lungs of Lupus-Prone Mice Quelled by Dietary Docosahexaenoic Acid Supplementation
Rajasinghe, Lichchavi D, Bates, Melissa A, Benninghoff, Abby D, Wierenga, Kathryn A, Harkema, Jack R, Pestka, James J
Published in Frontiers in immunology (21.01.2022)
Published in Frontiers in immunology (21.01.2022)
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Journal Article
Omega-3 Polyunsaturated Fatty Acid Intervention Against Established Autoimmunity in a Murine Model of Toxicant-Triggered Lupus
Pestka, James J, Akbari, Peyman, Wierenga, Kathryn A, Bates, Melissa A, Gilley, Kristen N, Wagner, James G, Lewandowski, Ryan P, Rajasinghe, Lichchavi D, Chauhan, Preeti S, Lock, Adam L, Li, Quan-Zhen, Harkema, Jack R
Published in Frontiers in immunology (07.04.2021)
Published in Frontiers in immunology (07.04.2021)
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Journal Article
Omega-3 Docosahexaenoic Acid (DHA) Impedes Silica-Induced Macrophage Corpse Accumulation by Attenuating Cell Death and Potentiating Efferocytosis
Rajasinghe, Lichchavi D, Chauhan, Preeti S, Wierenga, Kathryn A, Evered, Augustus O, Harris, Shamya N, Bates, Melissa A, Gavrilin, Mikhail A, Pestka, James J
Published in Frontiers in immunology (06.10.2020)
Published in Frontiers in immunology (06.10.2020)
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Journal Article
Comparative effects of human-equivalent low, moderate, and high dose oral prednisone intake on autoimmunity and glucocorticoid-related toxicity in a murine model of environmental-triggered lupus
Heine, Lauren K, Benninghoff, Abby D, Ross, Elizabeth A, Rajasinghe, Lichchavi D, Wagner, James G, Lewandowski, Ryan P, Richardson, Alexa L, Li, Quan-Zhen, Buchweitz, John P, Zyskowski, Justin, Tindle, Ashleigh N, Skedel, Anna E, Chargo, Nicholas J, McCabe, Laura R, Harkema, Jack R, Pestka, James J
Published in Frontiers in immunology (19.10.2022)
Published in Frontiers in immunology (19.10.2022)
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Journal Article