Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry
Zanger, Ulrich M, Raimundo, Sebastian, Eichelbaum, Michel
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.01.2004)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.01.2004)
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Impaired expression of CYP2D6 in intermediate metabolizers carrying the 41 allele caused by the intronic SNP 2988G>A: evidence for modulation of splicing events
Toscano, Claudia, Klein, Kathrin, Blievernicht, Julia, Schaeffeler, Elke, Saussele, Tanja, Raimundo, Sebastian, Eichelbaum, Michel, Schwab, Matthias, Zanger, Ulrich M
Published in Pharmacogenetics and genomics (01.10.2006)
Published in Pharmacogenetics and genomics (01.10.2006)
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A Natural Variant of the Heme-Binding Signature (R441C) Resulting in Complete Loss of Function of CYP2D6
KLEIN, Kathrin, TATZEL, Stephan, RAIMUNDO, Sebastian, SAUSSELE, Tanja, HUSTERT, Elisabeth, PLEISS, Jurgen, EICHELBAUM, Michel, ZANGER, Ulrich M
Published in Drug metabolism and disposition (01.08.2007)
Published in Drug metabolism and disposition (01.08.2007)
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Cloning and sequence of partial cDNAs encoding the human type V and VI adenylyl cyclases and subsequent RNA-quantification in various tissues
Raimundo, Sebastian, Giray, Jeanette, Volff, Jean-Nicolas, Schwab, Matthias, Altenbuchner, Joe, Ratge, Dieter, Wisser, Hermann
Published in Clinica chimica acta (01.07.1999)
Published in Clinica chimica acta (01.07.1999)
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Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6
Zanger, U M, Fischer, J, Raimundo, S, Stüven, T, Evert, B O, Schwab, M, Eichelbaum, M
Published in Pharmacogenetics (London) (01.10.2001)
Published in Pharmacogenetics (London) (01.10.2001)
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Journal Article
A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects
Raimundo, Sebastian, Toscano, Claudia, Klein, Kathrin, Fischer, Joachim, Griese, Ernst-Ulrich, Eichelbaum, Michel, Schwab, Matthias, Zanger, Ulrich M
Published in Clinical pharmacology and therapeutics (01.08.2004)
Published in Clinical pharmacology and therapeutics (01.08.2004)
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A silent mutation (2939G>A, exon 6; CYP2D659) leading to impaired expression and function of CYP2D6
Toscano, Claudia, Raimundo, Sebastian, Klein, Kathrin, Eichelbaum, Michel, Schwab, Matthias, Zanger, Ulrich M
Published in Pharmacogenetics and genomics (01.10.2006)
Published in Pharmacogenetics and genomics (01.10.2006)
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Journal Article