The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach
Raichur, Suryaprakash, Brunner, Bodo, Bielohuby, Maximilian, Hansen, Gitte, Pfenninger, Anja, Wang, Bing, Bruning, Jens C., Larsen, Philip Just, Tennagels, Norbert
Published in Molecular metabolism (Germany) (01.03.2019)
Published in Molecular metabolism (Germany) (01.03.2019)
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Journal Article
Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice
Ziegler, Nicole, Raichur, Suryaprakash, Brunner, Bodo, Hemmann, Ulrike, Stolte, Manuela, Schwahn, Uwe, Prochnow, Hans-Peter, Metz-Weidmann, Christiane, Tennagels, Norbert, Margerie, Daniel, Wohlfart, Paulus, Bielohuby, Maximilian
Published in Frontiers in endocrinology (Lausanne) (28.08.2020)
Published in Frontiers in endocrinology (Lausanne) (28.08.2020)
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Journal Article
Retinoid-related orphan receptor γ regulates several genes that control metabolism in skeletal muscle cells: links to modulation of reactive oxygen species production
Raichur, Suryaprakash, Lau, Patrick, Staels, Bart, Muscat, George E O
Published in Journal of molecular endocrinology (01.07.2007)
Published in Journal of molecular endocrinology (01.07.2007)
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Journal Article
CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance
Raichur, Suryaprakash, Wang, Siew Tein, Chan, Puck Wee, Li, Ying, Ching, Jianhong, Chaurasia, Bhagirath, Dogra, Shaillay, Öhman, Miina K., Takeda, Kosuke, Sugii, Shigeki, Pewzner-Jung, Yael, Futerman, Anthony H., Summers, Scott A.
Published in Cell metabolism (07.10.2014)
Published in Cell metabolism (07.10.2014)
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Journal Article
Mechanistic interplay between ceramide and insulin resistance
Reali, Federico, Morine, Melissa J, Kahramanoğulları, Ozan, Raichur, Suryaprakash, Schneider, Hans-Christoph, Crowther, Daniel, Priami, Corrado
Published in Scientific reports (23.01.2017)
Published in Scientific reports (23.01.2017)
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Journal Article
Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer’s and Parkinson’s diseases
Chai, Jin-Fang, Raichur, Suryaprakash, Khor, Ing Wei, Torta, Federico, Chew, Wee Siong, Herr, Deron Raymond, Ching, Jianhong, Kovalik, Jean-Paul, Khoo, Chin Meng, Wenk, Markus R, Tai, E Shyong, Sim, Xueling
Published in Human molecular genetics (15.01.2020)
Published in Human molecular genetics (15.01.2020)
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Journal Article
Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism: STAGGERER (SG/SG) MICE ARE RESISTANT TO DIET-INDUCED OBESITY
Lau, Patrick, Fitzsimmons, Rebecca L, Raichur, Suryaprakash, Wang, Shu-Ching M, Lechtken, Adriane, Muscat, George E.O
Published in The Journal of biological chemistry (27.06.2008)
Published in The Journal of biological chemistry (27.06.2008)
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Journal Article
CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance
Raichur, Suryaprakash, Wang, Siew Tein, Chan, Puck Wee, Li, Ying, Ching, Jianhong, Chaurasia, Bhagirath, Dogra, Shaillay, Öhman, Miina K., Takeda, Kosuke, Sugii, Shigeki, Pewzner-Jung, Yael, Futerman, Anthony H., Summers, Scott A.
Published in Cell metabolism (04.11.2014)
Published in Cell metabolism (04.11.2014)
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Journal Article
The Orphan Nuclear Receptor, NOR-1, a Target of β-Adrenergic Signaling, Regulates Gene Expression that Controls Oxidative Metabolism in Skeletal Muscle
Pearen, Michael A, Myers, Stephen A, Raichur, Suryaprakash, Ryall, James G, Lynch, Gordon S, Muscat, George E. O
Published in Endocrinology (Philadelphia) (01.06.2008)
Published in Endocrinology (Philadelphia) (01.06.2008)
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Journal Article
Histone deacetylase 5 regulates glucose uptake and insulin action in muscle cells
Raichur, Suryaprakash, Hooi Teh, Song, Ohwaki, Kenji, Gaur, Vidhi, Chau Long, Yun, Hargreaves, Mark, McGee, Sean L, Kusunoki, Jun
Published in Journal of molecular endocrinology (01.12.2012)
Published in Journal of molecular endocrinology (01.12.2012)
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Journal Article
Ragaglitazar: a novel PPARα & PPARγ agonist with potent lipid‐lowering and insulin‐sensitizing efficacy in animal models
Chakrabarti, Ranjan, Vikramadithyan, Reeba K, Misra, Parimal, Hiriyan, Jagadheshan, Raichur, Suryaprakash, Damarla, Ravi K, Gershome, Cynthia, Suresh, Juluri, Rajagopalan, Ramanujam
Published in British journal of pharmacology (01.10.2003)
Published in British journal of pharmacology (01.10.2003)
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Journal Article
Design, synthesis and evaluation of carbazole derivatives as PPARα/γ dual agonists and antioxidants
Kumar, Rakesh, Ramachandran, Uma, Srinivasan, Krishnamoorthy, Ramarao, Poduri, Raichur, Suryaprakash, Chakrabarti, Ranjan
Published in Bioorganic & medicinal chemistry (01.07.2005)
Published in Bioorganic & medicinal chemistry (01.07.2005)
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Journal Article
The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism
Lau, Patrick, Fitzsimmons, Rebecca L., Raichur, Suryaprakash, Wang, Shu-Ching M., Lechtken, Adriane, Muscat, George E.O.
Published in The Journal of biological chemistry (27.06.2008)
Published in The Journal of biological chemistry (27.06.2008)
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Journal Article
Biochemical mechanism of insulin sensitization, lipid modulation and anti-atherogenic potential of PPAR α/γ dual agonist: Ragaglitazar
Sharma, Sudhir, Sowjanya, Angaru, Kumari, Manju, Suryaprakash, Raichur, Cynthia, Gershome, Suresh, Juluri, Chakrabarti, Ranjan
Published in Life sciences (1973) (23.12.2006)
Published in Life sciences (1973) (23.12.2006)
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Journal Article
The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity
Lau, Patrick, Fitzsimmons, Rebecca L, Raichur, Suryaprakash, Wang, Shu-Ching M, Lechtken, Adriane, Muscat, George E O
Published in The Journal of biological chemistry (27.06.2008)
Published in The Journal of biological chemistry (27.06.2008)
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Journal Article
The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism
Patrick Lau, Rebecca L. Fitzsimmons, Suryaprakash Raichur, Shu-Ching M. Wang, Adriane Lechtken, George E. O. Muscat
Published in The Journal of biological chemistry (27.06.2008)
Published in The Journal of biological chemistry (27.06.2008)
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Journal Article
Synthesis, in vitro and in silico evaluation of l-tyrosine containing PPARalpha/gamma dual agonists
Kumar, Rakesh, Ramachandran, Uma, Khanna, Smriti, Bharatam, Prasad V, Raichur, Suryaprakash, Chakrabarti, Ranjan
Published in Bioorganic & medicinal chemistry (01.02.2007)
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Published in Bioorganic & medicinal chemistry (01.02.2007)
Journal Article