Considerations and caveats in anti-virulence drug development
Maura, Damien, Ballok, Alicia E, Rahme, Laurence G
Published in Current opinion in microbiology (01.10.2016)
Published in Current opinion in microbiology (01.10.2016)
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Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance
Hazan, Ronen, Que, Yok Ai, Maura, Damien, Strobel, Benjamin, Majcherczyk, Paul Anthony, Hopper, Laura Rose, Wilbur, David J., Hreha, Teri N., Barquera, Blanca, Rahme, Laurence G.
Published in Current biology (25.01.2016)
Published in Current biology (25.01.2016)
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A method for high throughput determination of viable bacteria cell counts in 96-well plates
Hazan, Ronen, Que, Yok-Ai, Maura, Damien, Rahme, Laurence G
Published in BMC microbiology (13.11.2012)
Published in BMC microbiology (13.11.2012)
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A quorum sensing small volatile molecule promotes antibiotic tolerance in bacteria
Que, Yok-Ai, Hazan, Ronen, Strobel, Benjamin, Maura, Damien, He, Jianxin, Kesarwani, Meenu, Panopoulos, Panagiotis, Tsurumi, Amy, Giddey, Marlyse, Wilhelmy, Julie, Mindrinos, Michael N, Rahme, Laurence G
Published in PloS one (19.12.2013)
Published in PloS one (19.12.2013)
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Molecular Insights into Function and Competitive Inhibition of Pseudomonas aeruginosa Multiple Virulence Factor Regulator
Kitao, Tomoe, Lepine, Francois, Babloudi, Seda, Walte, Frederick, Steinbacher, Stefan, Maskos, Klaus, Blaesse, Michael, Negri, Michele, Pucci, Michael, Zahler, Bob, Felici, Antonio, Rahme, Laurence G
Published in mBio (16.01.2018)
Published in mBio (16.01.2018)
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Interconnections of Pseudomonas aeruginosa Quorum-Sensing Systems in Intestinal Permeability and Inflammation
Singh, Vijay K, Almpani, Marianna, Wheeler, Kelsey M, Rahme, Laurence G
Published in mBio (25.04.2023)
Published in mBio (25.04.2023)
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Denver and Marshall scores successfully predict susceptibility to multiple independent infections in trauma patients
Almpani, Marianna, Tsurumi, Amy, Peponis, Thomas, Dhole, Yashoda V, Goodfield, Laura F, Tompkins, Ronald G, Rahme, Laurence G
Published in PloS one (29.04.2020)
Published in PloS one (29.04.2020)
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Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity
Starkey, Melissa, Lepine, Francois, Maura, Damien, Bandyopadhaya, Arunava, Lesic, Biljana, He, Jianxin, Kitao, Tomoe, Righi, Valeria, Milot, Sylvain, Tzika, Aria, Rahme, Laurence
Published in PLoS pathogens (01.08.2014)
Published in PLoS pathogens (01.08.2014)
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Genomic responses in mouse models poorly mimic human inflammatory diseases
Seok, Junhee, Warren, H. Shaw, Cuenca, Alex G., Mindrinos, Michael N., Baker, Henry V., Xu, Weihong, Richards, Daniel R., McDonald-Smith, Grace P., Gao, Hong, Hennessy, Laura, Finnerty, Celeste C., López, Cecilia M., Honari, Shari, Moore, Ernest E., Minei, Joseph P., Cuschieri, Joseph, Bankey, Paul E., Johnson, Jeffrey L., Sperry, Jason, Nathens, Avery B., Billiar, Timothy R., West, Michael A., Jeschke, Marc G., Klein, Matthew B., Gamelli, Richard L., Gibran, Nicole S., Brownstein, Bernard H., Miller-Graziano, Carol, Calvano, Steve E., Mason, Philip H., Cobb, J. Perren, Rahme, Laurence G., Lowry, Stephen F., Maier, Ronald V., Moldawer, Lyle L., Herndon, David N., Davis, Ronald W., Xiao, Wenzhong, Tompkins, Ronald G.
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
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A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes
Kesarwani, Meenu, Hazan, Ronen, He, Jianxin, Que, Yok-Ai, Que, Yokai, Apidianakis, Yiorgos, Lesic, Biliana, Xiao, Gaoping, Dekimpe, Valérie, Milot, Sylvain, Deziel, Eric, Lépine, François, Rahme, Laurence G
Published in PLoS pathogens (01.08.2011)
Published in PLoS pathogens (01.08.2011)
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Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy
Singh, Vijay K., Almpani, Marianna, Maura, Damien, Kitao, Tomoe, Ferrari, Livia, Fontana, Stefano, Bergamini, Gabriella, Calcaterra, Elisa, Pignaffo, Chiara, Negri, Michele, de Oliveira Pereira, Thays, Skinner, Frances, Gkikas, Manos, Andreotti, Danielle, Felici, Antonio, Déziel, Eric, Lépine, Francois, Rahme, Laurence G.
Published in Nature communications (30.08.2022)
Published in Nature communications (30.08.2022)
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