Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
Whyte, Warren A., Orlando, David A., Hnisz, Denes, Abraham, Brian J., Lin, Charles Y., Kagey, Michael H., Rahl, Peter B., Lee, Tong Ihn, Young, Richard A.
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
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Transcriptional Amplification in Tumor Cells with Elevated c-Myc
Lin, Charles Y., Lovén, Jakob, Rahl, Peter B., Paranal, Ronald M., Burge, Christopher B., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Published in Cell (28.09.2012)
Published in Cell (28.09.2012)
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Revisiting Global Gene Expression Analysis
Lovén, Jakob, Orlando, David A., Sigova, Alla A., Lin, Charles Y., Rahl, Peter B., Burge, Christopher B., Levens, David L., Lee, Tong Ihn, Young, Richard A.
Published in Cell (26.10.2012)
Published in Cell (26.10.2012)
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Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma
Chapuy, Bjoern, McKeown, Michael R., Lin, Charles Y., Monti, Stefano, Roemer, Margaretha G.M., Qi, Jun, Rahl, Peter B., Sun, Heather H., Yeda, Kelly T., Doench, John G., Reichert, Elaine, Kung, Andrew L., Rodig, Scott J., Young, Richard A., Shipp, Margaret A., Bradner, James E.
Published in Cancer cell (09.12.2013)
Published in Cancer cell (09.12.2013)
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Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms
Xiao, Sheng, Yosef, Nir, Yang, Jianfei, Wang, Yonghui, Zhou, Ling, Zhu, Chen, Wu, Chuan, Baloglu, Erkan, Schmidt, Darby, Ramesh, Radha, Lobera, Mercedes, Sundrud, Mark S., Tsai, Pei-Yun, Xiang, Zhijun, Wang, Jinsong, Xu, Yan, Lin, Xichen, Kretschmer, Karsten, Rahl, Peter B., Young, Richard A., Zhong, Zhong, Hafler, David A., Regev, Aviv, Ghosh, Shomir, Marson, Alexander, Kuchroo, Vijay K.
Published in Immunity (Cambridge, Mass.) (17.04.2014)
Published in Immunity (Cambridge, Mass.) (17.04.2014)
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Mediator and cohesin connect gene expression and chromatin architecture
Taatjes, Dylan J, van Berkum, Nynke L, Young, Richard A, Kagey, Michael H, Bilodeau, Steve, Zhan, Ye, Ebmeier, Christopher C, Levine, Stuart S, Newman, Jamie J, Rahl, Peter B, Dekker, Job, Goossens, Jesse, Orlando, David A
Published in Nature (London) (23.09.2010)
Published in Nature (London) (23.09.2010)
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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
Kwiatkowski, Nicholas, Zhang, Tinghu, Rahl, Peter B., Abraham, Brian J., Reddy, Jessica, Ficarro, Scott B., Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Catherine E., Hannett, Nancy M., McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, Thomas, Mitsiades, Constantine S., Weng, Andrew P., Brown, Jennifer R., Benes, Cyril H., Marto, Jarrod A., Young, Richard A., Gray, Nathanael S.
Published in Nature (London) (31.07.2014)
Published in Nature (London) (31.07.2014)
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Divergent Transcription from Active Promoters
Seila, Amy C, Calabrese, J. Mauro, Levine, Stuart S, Yeo, Gene W, Rahl, Peter B, Flynn, Ryan A, Young, Richard A, Sharp, Phillip A
Published in Science (American Association for the Advancement of Science) (19.12.2008)
Published in Science (American Association for the Advancement of Science) (19.12.2008)
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c-Myc Regulates Transcriptional Pause Release
Rahl, Peter B., Lin, Charles Y., Seila, Amy C., Flynn, Ryan A., McCuine, Scott, Burge, Christopher B., Sharp, Phillip A., Young, Richard A.
Published in Cell (30.04.2010)
Published in Cell (30.04.2010)
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Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes
Cheng, Bo, Li, Tiandao, Rahl, Peter B., Adamson, Todd E., Loudas, Nicholas B., Guo, Jiannan, Varzavand, Katayoun, Cooper, Jeffrey J., Hu, Xiaopeng, Gnatt, Averell, Young, Richard A., Price, David H.
Published in Molecular cell (13.01.2012)
Published in Molecular cell (13.01.2012)
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Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
Giraud, Matthieu, Yoshida, Hideyuki, Abramson, Jakub, Rahl, Peter B, Young, Richard A, Mathis, Diane, Benoist, Christophe
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2012)
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BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Delmore, Jake E., Issa, Ghayas C., Lemieux, Madeleine E., Rahl, Peter B., Shi, Junwei, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M., Qi, Jun, Chesi, Marta, Schinzel, Anna C., McKeown, Michael R., Heffernan, Timothy P., Vakoc, Christopher R., Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G., Young, Richard A., Hahn, William C., Anderson, Kenneth C., Kung, Andrew L., Bradner, James E., Mitsiades, Constantine S.
Published in Cell (16.09.2011)
Published in Cell (16.09.2011)
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DHODH modulates transcriptional elongation in the neural crest and melanoma
White, Richard Mark, Cech, Jennifer, Ratanasirintrawoot, Sutheera, Lin, Charles Y., Rahl, Peter B., Burke, Christopher J., Langdon, Erin, Tomlinson, Matthew L., Mosher, Jack, Kaufman, Charles, Chen, Frank, Long, Hannah K., Kramer, Martin, Datta, Sumon, Neuberg, Donna, Granter, Scott, Young, Richard A., Morrison, Sean, Wheeler, Grant N., Zon, Leonard I.
Published in Nature (London) (24.03.2011)
Published in Nature (London) (24.03.2011)
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BET bromodomain proteins regulate enhancer function during adipogenesis
Brown, Jonathan D., Feldman, Zachary B., Doherty, Sean P., Reyes, Jaime M., Rahl, Peter B., Lin, Charles Y., Sheng, Quanhu, Duan, Qiong, Federation, Alexander J., Kung, Andrew L., Haldar, Saptarsi M., Young, Richard A., Plutzky, Jorge, Bradner, James E.
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2018)
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Genome-wide localization of small molecules
Anders, Lars, Guenther, Matthew G, Qi, Jun, Fan, Zi Peng, Marineau, Jason J, Rahl, Peter B, Lovén, Jakob, Sigova, Alla A, Smith, William B, Lee, Tong Ihn, Bradner, James E, Young, Richard A
Published in Nature biotechnology (01.01.2014)
Published in Nature biotechnology (01.01.2014)
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MYC and transcription elongation
Rahl, Peter B, Young, Richard A
Published in Cold Spring Harbor perspectives in medicine (01.01.2014)
Published in Cold Spring Harbor perspectives in medicine (01.01.2014)
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Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts
Gurtan, Allan M, Ravi, Arvind, Rahl, Peter B, Bosson, Andrew D, JnBaptiste, Courtney K, Bhutkar, Arjun, Whittaker, Charles A, Young, Richard A, Sharp, Phillip A
Published in Genes & development (15.04.2013)
Published in Genes & development (15.04.2013)
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Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma
Chapuy, Bjoern, McKeown, Michael R., Lin, Charles Y., Monti, Stefano, Roemer, Margaretha G.M., Qi, Jun, Rahl, Peter B., Sun, Heather H., Yeda, Kelly T., Doench, John G., Reichert, Elaine, Kung, Andrew L., Rodig, Scott J., Young, Richard A., Shipp, Margaret A., Bradner, James E.
Published in Cancer cell (14.04.2014)
Published in Cancer cell (14.04.2014)
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