Mineralocorticoid receptors are present in skeletal muscle and represent a potential therapeutic target
Chadwick, Jessica A, Hauck, J Spencer, Lowe, Jeovanna, Shaw, Jeremiah J, Guttridge, Denis C, Gomez-Sanchez, Celso E, Gomez-Sanchez, Elise P, Rafael-Fortney, Jill A
Published in The FASEB journal (01.11.2015)
Published in The FASEB journal (01.11.2015)
Get more information
Journal Article
Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy
Lowe, Jeovanna, Kolkhof, Peter, Haupt, Michael J., Peczkowski, Kyra K., Rastogi, Neha, Hauck, J. Spencer, Kadakia, Feni K., Zins, Jonathan G., Ciccone, Pierce C., Smart, Suzanne, Sandner, Peter, Raman, Subha V., Janssen, Paul M.L., Rafael‐Fortney, Jill A.
Published in ESC Heart Failure (01.12.2020)
Published in ESC Heart Failure (01.12.2020)
Get full text
Journal Article
Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, double-blind, placebo-controlled trial
Raman, Subha V, Dr, Hor, Kan N, MD, Mazur, Wojciech, MD, Halnon, Nancy J, MD, Kissel, John T, MD, He, Xin, PhD, Tran, Tam, BS, Smart, Suzanne, BS, McCarthy, Beth, RT, Taylor, Michael D, MD, Jefferies, John L, MD, Rafael-Fortney, Jill A, PhD, Lowe, Jeovanna, MS, Roble, Sharon L, MD, Cripe, Linda H, MD
Published in Lancet neurology (01.02.2015)
Published in Lancet neurology (01.02.2015)
Get full text
Journal Article
Cell-type specific effects of mineralocorticoid receptor gene expression suggest intercellular communication regulating fibrosis in skeletal muscle disease
Gomatam, Chetan K, Ingale, Pratham, Rodriguez, Gabriel, Munger, Sarah, Pomeranets, Rachel, Krishna, Swathy, Lowe, Jeovanna, Howard, Zachary M, Rafael-Fortney, Jill A
Published in Frontiers in physiology (2024)
Published in Frontiers in physiology (2024)
Get full text
Journal Article
Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function?
Bal, Naresh C, Gupta, Subash C, Pant, Meghna, Sopariwala, Danesh H, Gonzalez-Escobedo, Geoffrey, Turner, Joanne, Gunn, John S, Pierson, Christopher R, Harper, Scott Q, Rafael-Fortney, Jill A, Periasamy, Muthu
Published in Frontiers in physiology (01.03.2021)
Published in Frontiers in physiology (01.03.2021)
Get full text
Journal Article
Mineralocorticoid receptor antagonists improve membrane integrity independent of muscle force in muscular dystrophy
Hauck, J Spencer, Lowe, Jeovanna, Rastogi, Neha, McElhanon, Kevin E, Petrosino, Jennifer M, Peczkowski, Kyra K, Chadwick, Ashlee N, Zins, Jonathan G, Accornero, Federica, Janssen, Paul M L, Weisleder, Noah L, Rafael-Fortney, Jill A
Published in Human molecular genetics (15.06.2019)
Published in Human molecular genetics (15.06.2019)
Get full text
Journal Article
Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease
Shettigar, Vikram, Zhang, Bo, Little, Sean C., Salhi, Hussam E., Hansen, Brian J., Li, Ning, Zhang, Jianchao, Roof, Steve R., Ho, Hsiang-Ting, Brunello, Lucia, Lerch, Jessica K., Weisleder, Noah, Fedorov, Vadim V., Accornero, Federica, Rafael-Fortney, Jill A., Gyorke, Sandor, Janssen, Paul M. L., Biesiadecki, Brandon J., Ziolo, Mark T., Davis, Jonathan P.
Published in Nature communications (24.02.2016)
Published in Nature communications (24.02.2016)
Get full text
Journal Article
Prednisolone attenuates improvement of cardiac and skeletal contractile function and histopathology by lisinopril and spironolactone in the mdx mouse model of Duchenne muscular dystrophy
Janssen, Paul M L, Murray, Jason D, Schill, Kevin E, Rastogi, Neha, Schultz, Eric J, Tran, Tam, Raman, Subha V, Rafael-Fortney, Jill A
Published in PloS one (13.02.2014)
Published in PloS one (13.02.2014)
Get full text
Journal Article
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy
Chadwick, Jessica A, Swager, Sarah A, Lowe, Jeovanna, Welc, Steven S, Tidball, James G, Gomez-Sanchez, Celso E, Gomez-Sanchez, Elise P, Rafael-Fortney, Jill A
Published in Human molecular genetics (01.12.2016)
Published in Human molecular genetics (01.12.2016)
Get full text
Journal Article
Corrigendum: Muscle Twitch Kinetics Are Dependent on Muscle Group, Disease State, and Age in Duchenne Muscular Dystrophy Mouse Models
Peczkowski, Kyra K, Rastogi, Neha, Lowe, Jeovanna, Floyd, Kyle T, Schultz, Eric J, Karaze, Tallib, Davis, Jonathan P, Rafael-Fortney, Jill A, Janssen, Paul M L
Published in Frontiers in physiology (05.01.2022)
Published in Frontiers in physiology (05.01.2022)
Get full text
Journal Article
Muscle Twitch Kinetics Are Dependent on Muscle Group, Disease State, and Age in Duchenne Muscular Dystrophy Mouse Models
Peczkowski, Kyra K, Rastogi, Neha, Lowe, Jeovanna, Floyd, Kyle T, Schultz, Eric J, Karaze, Tallib, Davis, Jonathan P, Rafael-Fortney, Jill A, Janssen, Paul M L
Published in Frontiers in physiology (25.09.2020)
Published in Frontiers in physiology (25.09.2020)
Get full text
Journal Article
Dystrophin glycoprotein complex dysfunction: A regulatory link between muscular dystrophy and cancer cachexia
Acharyya, Swarnali, Butchbach, Matthew E.R., Sahenk, Zarife, Wang, Huating, Saji, Motoyasu, Carathers, Micheal, Ringel, Matthew D., Skipworth, Richard J.E., Fearon, Kenneth C.H., Hollingsworth, Michael A., Muscarella, Peter, Burghes, Arthur H.M., Rafael-Fortney, Jill A., Guttridge, Denis C.
Published in Cancer cell (01.11.2005)
Published in Cancer cell (01.11.2005)
Get full text
Journal Article
Micro-dystrophin gene therapy demonstrates long-term cardiac efficacy in a severe Duchenne muscular dystrophy model
Piepho, Arden B., Lowe, Jeovanna, Cumby, Laurel R., Dorn, Lisa E., Lake, Dana M., Rastogi, Neha, Gertzen, Megan D., Sturgill, Sarah L., Odom, Guy L., Ziolo, Mark T., Accornero, Federica, Chamberlain, Jeffrey S., Rafael-Fortney, Jill A.
Published in Molecular therapy. Methods & clinical development (09.03.2023)
Published in Molecular therapy. Methods & clinical development (09.03.2023)
Get full text
Journal Article
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy
Howard, Zachary M, Gomatam, Chetan K, Rabolli, Charles P, Lowe, Jeovanna, Piepho, Arden B, Bansal, Shyam S, Accornero, Federica, Rafael-Fortney, Jill A
Published in JCI insight (10.10.2022)
Published in JCI insight (10.10.2022)
Get full text
Journal Article
Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model
Howard, Zachary M, Dorn, Lisa E, Lowe, Jeovanna, Gertzen, Megan D, Ciccone, Pierce, Rastogi, Neha, Odom, Guy L, Accornero, Federica, Chamberlain, Jeffrey S, Rafael-Fortney, Jill A
Published in JCI insight (08.04.2021)
Published in JCI insight (08.04.2021)
Get full text
Journal Article
Mineralocorticoid Receptor Signaling Contributes to Normal Muscle Repair After Acute Injury
Hauck, J Spencer, Howard, Zachary M, Lowe, Jeovanna, Rastogi, Neha, Pico, Madison G, Swager, Sarah A, Petrosino, Jennifer M, Gomez-Sanchez, Celso E, Gomez-Sanchez, Elise P, Accornero, Federica, Rafael-Fortney, Jill A
Published in Frontiers in physiology (25.10.2019)
Published in Frontiers in physiology (25.10.2019)
Get full text
Journal Article
Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice
Janssen, Paul M. L, Hiranandani, Nitisha, Mays, Tessily A, Rafael-Fortney, Jill A
Published in American journal of physiology. Heart and circulatory physiology (01.12.2005)
Published in American journal of physiology. Heart and circulatory physiology (01.12.2005)
Get full text
Journal Article
Glutamate receptors localize postsynaptically at neuromuscular junctions in mice
Mays, Tessily A., Sanford, Jamie L., Hanada, Toshihiko, Chishti, Athar H., Rafael-Fortney, Jill A.
Published in Muscle & nerve (01.03.2009)
Published in Muscle & nerve (01.03.2009)
Get full text
Journal Article