Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
McBrien, Julia Bergild, Mavigner, Maud, Franchitti, Lavinia, Smith, S. Abigail, White, Erick, Tharp, Gregory K., Walum, Hasse, Busman-Sahay, Kathleen, Aguilera-Sandoval, Christian R., Thayer, William O., Spagnuolo, Rae Ann, Kovarova, Martina, Wahl, Angela, Cervasi, Barbara, Margolis, David M., Vanderford, Thomas H., Carnathan, Diane G., Paiardini, Mirko, Lifson, Jeffrey D., Lee, John H., Safrit, Jeffrey T., Bosinger, Steven E., Estes, Jacob D., Derdeyn, Cynthia A., Garcia, J. Victor, Kulpa, Deanna A., Chahroudi, Ann, Silvestri, Guido
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
Get full text
Journal Article
Ultra-long-acting removable drug delivery system for HIV treatment and prevention
Kovarova, Martina, Benhabbour, S. Rahima, Massud, Ivana, Spagnuolo, Rae Ann, Skinner, Brianna, Baker, Caroline E., Sykes, Craig, Mollan, Katie R., Kashuba, Angela D. M., García-Lerma, J. Gerardo, Mumper, Russell J., Garcia, J. Victor
Published in Nature communications (08.10.2018)
Published in Nature communications (08.10.2018)
Get full text
Journal Article
Generation of HIV Latency in Humanized BLT Mice
DENTON, Paul W, OLESEN, Rikke, MARGOLIS, David M, GARCIA, J. Victor, CHOUDHARY, Shailesh K, ARCHIN, Nancy M, WAHL, Angela, SWANSON, Michael D, CHATEAU, Morgan, NOCHI, Tomonori, KRISKO, John F, SPAGNUOLO, Rae Ann
Published in Journal of Virology (01.01.2012)
Published in Journal of Virology (01.01.2012)
Get full text
Journal Article
Analysis of the effect of HDAC inhibitors on the formation of the HIV reservoir
Ling, Lijun, Kim, Manse, Soper, Andrew, Kovarova, Martina, Spagnuolo, Rae Ann, Begum, Nurjahan, Kirchherr, Jennifer, Archin, Nancie, Battaglia, Diana, Cleveland, Dave, Wahl, Angela, Margolis, David M, Browne, Edward P, Garcia, J Victor
Published in mBio (11.09.2024)
Published in mBio (11.09.2024)
Get full text
Journal Article
Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice
Ling, Lijun, De, Chandrav, Spagnuolo, Rae Ann, Begum, Nurjahan, Falcinelli, Shane D, Archin, Nancie M, Kovarova, Martina, Silvestri, Guido, Wahl, Angela, Margolis, David M, Garcia, J Victor
Published in PLoS pathogens (01.12.2023)
Published in PLoS pathogens (01.12.2023)
Get full text
Journal Article
Loss of In Vivo Replication Fitness of HIV-1 Variants Resistant to the Tat Inhibitor, dCA
Ling, Lijun, Leda, Ana R, Begum, Nurjahan, Spagnuolo, Rae Ann, Wahl, Angela, Garcia, J Victor, Valente, Susana T
Published in Viruses (01.04.2023)
Published in Viruses (01.04.2023)
Get full text
Journal Article
Targeted cytotoxic therapy kills persisting HIV infected cells during ART
Denton, Paul W, Long, Julie M, Wietgrefe, Stephen W, Sykes, Craig, Spagnuolo, Rae Ann, Snyder, Olivia D, Perkey, Katherine, Archin, Nancie M, Choudhary, Shailesh K, Yang, Kuo, Hudgens, Michael G, Pastan, Ira, Haase, Ashley T, Kashuba, Angela D, Berger, Edward A, Margolis, David M, Garcia, J Victor
Published in PLoS pathogens (01.01.2014)
Published in PLoS pathogens (01.01.2014)
Get full text
Journal Article
A long-acting formulation of the integrase inhibitor raltegravir protects humanized BLT mice from repeated high-dose vaginal HIV challenges
Kovarova, Martina, Swanson, Michael D, Sanchez, Rosa I, Baker, Caroline E, Steve, Justin, Spagnuolo, Rae Ann, Howell, Bonnie J, Hazuda, Daria J, Garcia, J Victor
Published in Journal of antimicrobial chemotherapy (01.06.2016)
Published in Journal of antimicrobial chemotherapy (01.06.2016)
Get full text
Journal Article
HIV co-infection augments EBV-induced tumorigenesis in vivo
Whitehurst, Christopher B, Rizk, Monica, Teklezghi, Adonay, Spagnuolo, Rae Ann, Pagano, Joseph S, Wahl, Angela
Published in Frontiers in virology (online) (01.01.2022)
Published in Frontiers in virology (online) (01.01.2022)
Get full text
Journal Article
Macrophages sustain HIV replication in vivo independently of T cells
Honeycutt, Jenna B, Wahl, Angela, Baker, Caroline, Spagnuolo, Rae Ann, Foster, John, Zakharova, Oksana, Wietgrefe, Stephen, Caro-Vegas, Carolina, Madden, Victoria, Sharpe, Garrett, Haase, Ashley T, Eron, Joseph J, Garcia, J Victor
Published in The Journal of clinical investigation (01.04.2016)
Published in The Journal of clinical investigation (01.04.2016)
Get full text
Journal Article
ORIGINAL ARTICLE: Quantification and Comparison of Toll-Like Receptor Expression and Responsiveness in Primary and Immortalized Human Female Lower Genital Tract Epithelia
Herbst-Kralovetz, Melissa M., Quayle, Alison J., Ficarra, Mercedes, Greene, Sheila, Rose II, William A., Chesson, Ralph, Spagnuolo, Rae Ann, Pyles, Richard B.
Published in American journal of reproductive immunology (1989) (01.03.2008)
Published in American journal of reproductive immunology (1989) (01.03.2008)
Get full text
Journal Article
Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo
Nixon, Christopher C., Mavigner, Maud, Sampey, Gavin C., Brooks, Alyssa D., Spagnuolo, Rae Ann, Irlbeck, David M., Mattingly, Cameron, Ho, Phong T., Schoof, Nils, Cammon, Corinne G., Tharp, Greg K., Kanke, Matthew, Wang, Zhang, Cleary, Rachel A., Upadhyay, Amit A., De, Chandrav, Wills, Saintedym R., Falcinelli, Shane D., Galardi, Cristin, Walum, Hasse, Schramm, Nathaniel J., Deutsch, Jennifer, Lifson, Jeffrey D., Fennessey, Christine M., Keele, Brandon F., Jean, Sherrie, Maguire, Sean, Liao, Baolin, Browne, Edward P., Ferris, Robert G., Brehm, Jessica H., Favre, David, Vanderford, Thomas H., Bosinger, Steven E., Jones, Corbin D., Routy, Jean-Pierre, Archin, Nancie M., Margolis, David M., Wahl, Angela, Dunham, Richard M., Silvestri, Guido, Chahroudi, Ann, Garcia, J. Victor
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
Get full text
Journal Article
Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice
Lijun Ling, Chandrav De, Rae Ann Spagnuolo, Nurjahan Begum, Shane D Falcinelli, Nancie M Archin, Martina Kovarova, Guido Silvestri, Angela Wahl, David M Margolis, J Victor Garcia
Published in PLoS pathogens (01.12.2023)
Published in PLoS pathogens (01.12.2023)
Get full text
Journal Article
Transient CD4.sup.+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice
Ling, Lijun, De, Chandrav, Spagnuolo, Rae Ann, Begum, Nurjahan, Falcinelli, Shane D, Archin, Nancie M, Kovarova, Martina, Silvestri, Guido, Wahl, Angela, Margolis, David M, Garcia, J. Victor
Published in PLoS pathogens (06.12.2023)
Published in PLoS pathogens (06.12.2023)
Get full text
Journal Article
Role of Semen on Vaginal HIV-1 Transmission and Maraviroc Protection
Council, Olivia D, Swanson, Michael D, Spagnuolo, Rae Ann, Wahl, Angela, Garcia, J Victor
Published in Antimicrobial agents and chemotherapy (01.12.2015)
Published in Antimicrobial agents and chemotherapy (01.12.2015)
Get full text
Journal Article
In vivo analysis of the effect of panobinostat on cell-associated HIV RNA and DNA levels and latent HIV infection
Tsai, Perry, Wu, Guoxin, Baker, Caroline E, Thayer, William O, Spagnuolo, Rae Ann, Sanchez, Rosa, Barrett, Stephanie, Howell, Bonnie, Margolis, David, Hazuda, Daria J, Archin, Nancie M, Garcia, J Victor
Published in Retrovirology (21.05.2016)
Published in Retrovirology (21.05.2016)
Get full text
Journal Article
HIV pre-exposure prophylaxis for women and infants prevents vaginal and oral HIV transmission in a preclinical model of HIV infection
Kovarova, Martina, Shanmugasundaram, Uma, Baker, Caroline E, Spagnuolo, Rae Ann, De, Chandrav, Nixon, Christopher C, Wahl, Angela, Garcia, J Victor
Published in Journal of antimicrobial chemotherapy (01.11.2016)
Published in Journal of antimicrobial chemotherapy (01.11.2016)
Get full text
Journal Article
Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity
Wahl, Angela, Baker, Caroline, Spagnuolo, Rae Ann, Stamper, Lisa W, Fouda, Genevieve G, Permar, Sallie R, Hinde, Katie, Kuhn, Louise, Bode, Lars, Aldrovandi, Grace M, Garcia, J Victor
Published in Journal of virology (01.11.2015)
Published in Journal of virology (01.11.2015)
Get full text
Journal Article