Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine
STEARNS, Vered, JOHNSON, Michael D, RAE, James M, MOROCHO, Alan, NOVIELLI, Antonella, BHARGAVA, Pankaj, HAYES, Daniel F, DESTA, Zeruesenay, FLOCKHART, David A
Published in JNCI : Journal of the National Cancer Institute (03.12.2003)
Published in JNCI : Journal of the National Cancer Institute (03.12.2003)
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CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment
Jin, Yan, Desta, Zeruesenay, Stearns, Vered, Ward, Bryan, Ho, Herbert, Lee, Kyung-Hoon, Skaar, Todd, Storniolo, Anna Maria, Li, Lang, Araba, Adjei, Blanchard, Rebecca, Nguyen, Anne, Ullmer, Lynda, Hayden, Jill, Lemler, Suzanne, Weinshilboum, Richard M., Rae, James M., Hayes, Daniel F., Flockhart, David A.
Published in JNCI : Journal of the National Cancer Institute (05.01.2005)
Published in JNCI : Journal of the National Cancer Institute (05.01.2005)
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Rifampin Is a Selective, Pleiotropic Inducer of Drug Metabolism Genes in Human Hepatocytes: Studies with cDNA and Oligonucleotide Expression Arrays
Rae, J M, Johnson, M D, Lippman, M E, Flockhart, D A
Published in The Journal of pharmacology and experimental therapeutics (01.12.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.12.2001)
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Pharmacogenetics of Tamoxifen Biotransformation Is Associated With Clinical Outcomes of Efficacy and Hot Flashes
GOETZ, Matthew P, RAE, James M, DESTA, Zeruesenay, PEREZ, Edith A, INGLE, James N, SUMAN, Vera J, SAFGREN, Stephanie L, AMES, Matthew M, VISSCHER, Daniel W, REYNOLDS, Carol, COUCH, Fergus J, LINGLE, Wilma L, FLOCKHART, David A
Published in Journal of clinical oncology (20.12.2005)
Published in Journal of clinical oncology (20.12.2005)
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Activation of mitogen-activated protein kinase in estrogen receptor α-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor α-negative human breast tumors
CREIGHTON, Chad J, HILGER, Amy M, MURTHY, Shalini, RAE, James M, CHINNAIYAN, Arul M, EL-ASHRY, Dorraya
Published in Cancer research (Chicago, Ill.) (01.04.2006)
Published in Cancer research (Chicago, Ill.) (01.04.2006)
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CYP2D6 genotype is not associated with survival in breast cancer patients treated with tamoxifen: results from a population-based study
Hertz, D. L., Kidwell, K. M., Hilsenbeck, S. G., Oesterreich, S., Osborne, C. K., Philips, S., Chenault, C., Hartmaier, R. J., Skaar, T. C., Sikora, M. J., Rae, J. M.
Published in Breast cancer research and treatment (01.11.2017)
Published in Breast cancer research and treatment (01.11.2017)
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Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
NOWELL, Susan A, AHN, Jiyoung, RAE, James M, SCHEYS, Joshua O, TROVATO, Andrew, SWEENEY, Carol, MACLEOD, Stewart L, KADLUBAR, Fred F, AMBROSONE, Christine B
Published in Breast cancer research and treatment (01.06.2005)
Published in Breast cancer research and treatment (01.06.2005)
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Journal Article
Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen
JOHNSON, Michael D, HONG ZUO, LEE, Kyung-Hoon, TREBLEY, Joseph P, RAE, James Michael, WEATHERMAN, Ross V, DESTA, Zeruesanay, FLOCKHART, David A, SKAAR, Todd C
Published in Breast cancer research and treatment (01.05.2004)
Published in Breast cancer research and treatment (01.05.2004)
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Abstract P6-09-02: Analysis of the International tamoxifen pharmacogenomics consortium (ITPC) dataset shows that genotyping DNA derived from tumor does not introduce CYP2D6 genotyping error or mask an association with tamoxifen efficacy
Kidwell, KM, Hertz, DL, Leyland-Jones, B, Regan, MM, Dowsett, M, Rae, JM
Published in Cancer research (Chicago, Ill.) (15.02.2016)
Published in Cancer research (Chicago, Ill.) (15.02.2016)
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Abstract P6-13-05: Androgen receptor (AR): A novel target and mechanism for radiosensitization and treatment in triple-negative breast cancers (TNBC)
Speers, C, Zhao, SG, Liu, M, Rae, JM, Hayes, DF, Feng, FY, Pierce, LJ
Published in Cancer research (Chicago, Ill.) (15.02.2016)
Published in Cancer research (Chicago, Ill.) (15.02.2016)
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Abstract P6-09-11: Genetic variation in CYP3A affects steady-state exemestane concentrations but does not explain inter-race difference
Hertz, DL, Kidwell, KM, Gersch, CL, Desta, Z, Storniolo, AM, Stearns, V, Skaar, TC, Hayes, DF, Henry, NL, Rae, JM
Published in Cancer research (Chicago, Ill.) (15.02.2017)
Published in Cancer research (Chicago, Ill.) (15.02.2017)
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GREB1 is a critical regulator of hormone dependent breast cancer growth
RAE, James M, JOHNSON, Michael D, SCHEYS, Joshua O, CORDERO, Kevin E, LARIOS, José M, LIPPMAN, Marc E
Published in Breast cancer research and treatment (01.07.2005)
Published in Breast cancer research and treatment (01.07.2005)
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Abstract P3-07-36: Immune related gene expression signatures predict benefit of letrozole over tamoxifen in BIG 1-98
Willis, S, Gray, KP, Regan, MM, Rae, JM, Kammler, R, Young, B, Ditzel, HJ, Lyng, MB, Colleoni, M, Viale, G, Leyland-Jones, B
Published in Cancer research (Chicago, Ill.) (15.02.2016)
Published in Cancer research (Chicago, Ill.) (15.02.2016)
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Abstract P3-07-23: CYP2D6 genotype and breast cancer recurrence in tamoxifen treated patients: An evaluation of the importance of loss-of-heterozygosity
Ahern, TP, Hertz, DL, Damkier, P, Ejlertsen, B, Hamilton-Dutoit, SJ, Rae, JM, Regan, MM, Thompson, AM, Lash, TL, Cronin-Fenton, DP
Published in Cancer research (Chicago, Ill.) (15.02.2016)
Published in Cancer research (Chicago, Ill.) (15.02.2016)
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Abstract S4-05: Interrogating the landscape of long noncoding RNAs in breast cancer to identify predictors of tamoxifen resistance
Feng, FY, Niknafs, Y, Han, S, Ma, T, Speers, C, Malik, R, Evans, J, Zhang, C, Pierce, LJ, Hayes, DF, Rae, JM, Chinnaiyan, AM
Published in Cancer research (Chicago, Ill.) (15.02.2016)
Published in Cancer research (Chicago, Ill.) (15.02.2016)
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Evaluating the Impact of CYP3A5 Genotype on Post-Transplant Healthcare Resource Utilization in Pediatric Renal and Heart Transplant Recipients Receiving Tacrolimus
Pasternak, Amy L, Marshall, Vincent D, Gersch, Christina L, Rae, James M, Englesbe, Michael, Park, Jeong M
Published in Pharmacogenomics and personalized medicine (01.01.2021)
Published in Pharmacogenomics and personalized medicine (01.01.2021)
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Abstract PD7-07: Discovery of molecular predictors of late breast cancer specific events (BCSE) in ER+, node+ breast cancer – new transcriptome expression whole gene analysis of the phase III adjuvant trial SWOG S8814
Albain, KS, Crager, MR, Barlow, WE, Baehner, FL, Bergamaschi, A, Rae, JM, Ravdin, PM, Tripathy, D, Gralow, JR, Livingston, RB, Osborne, CK, Ingle, JN, Pritchard, KI, Davidson, NE, Carey, LA, Cherbavaz, DB, Sing, AP, Shak, S, Hortobagyi, GN, Hayes, DF
Published in Cancer research (Chicago, Ill.) (15.02.2017)
Published in Cancer research (Chicago, Ill.) (15.02.2017)
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Functional characterization of the G162R and D216H genetic variants of human CYP17A1
Capper, C.P., Liu, J., McIntosh, L.R., Larios, J.M., Johnson, M.D., Hollenberg, P.F., Osawa, Y., Auchus, R.J., Rae, J.M.
Published in The Journal of steroid biochemistry and molecular biology (01.04.2018)
Published in The Journal of steroid biochemistry and molecular biology (01.04.2018)
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Abstract P3-05-01: Molecular analysis of cancer tissue, circulating tumor cells (CTC) and cell-free plasma tumor DNA (ptDNA) suggests variable mechanisms of resistance to endocrine therapy (ET) in estrogen receptor (ER) positive metastatic breast cancer (MBC)
Paoletti, C, Aung, K, Cannell, EM, Darga, EP, Chu, D, Kidwell, KM, Thomas, DG, Tokudome, N, Brown, ME, McNutt, LM, Gersch, C, Schott, AF, Park, BH, Robinson, DR, Chinnaiyan, AM, Rae, JM, Hayes, DF
Published in Cancer research (Chicago, Ill.) (15.02.2016)
Published in Cancer research (Chicago, Ill.) (15.02.2016)
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