Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer
Kemp, Samantha B, Cheng, Noah, Markosyan, Nune, Sor, Rina, Kim, Il-Kyu, Hallin, Jill, Shoush, Jason, Quinones, Liz, Brown, Natalie V, Bassett, Jared B, Joshi, Nikhil, Yuan, Salina, Smith, Molly, Vostrejs, William P, Perez-Vale, Kia Z, Kahn, Benjamin, Mo, Feiyan, Donahue, Timothy R, Radu, Caius G, Clendenin, Cynthia, Christensen, James G, Vonderheide, Robert H, Stanger, Ben Z
Published in Cancer discovery (06.02.2023)
Published in Cancer discovery (06.02.2023)
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Mechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate Cancer
Stuparu, Andreea D, Capri, Joseph R, Meyer, Catherine A L, Le, Thuc M, Evans-Axelsson, Susan L, Current, Kyle, Lennox, Mark, Mona, Christine E, Fendler, Wolfgang P, Calais, Jeremie, Eiber, Matthias, Dahlbom, Magnus, Czernin, Johannes, Radu, Caius G, Lückerath, Katharina, Slavik, Roger
Published in Journal of Nuclear Medicine (01.07.2021)
Published in Journal of Nuclear Medicine (01.07.2021)
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Supramolecular Approach for Preparation of Size-Controlled Nanoparticles
Wang, Hao, Wang, Shutao, Su, Helen, Chen, Kuan-Ju, Armijo, Amanda Lee, Lin, Wei-Yu, Wang, Yanju, Sun, Jing, Kamei, Ken-ichiro, Czernin, Johannes, Radu, Caius G, Tseng, Hsian-Rong
Published in Angewandte Chemie (International ed.) (01.01.2009)
Published in Angewandte Chemie (International ed.) (01.01.2009)
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Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity
Abt, Evan R, Rashid, Khalid, Le, Thuc M, Li, Suwen, Lee, Hailey R, Lok, Vincent, Li, Luyi, Creech, Amanda L, Labora, Amanda N, Mandl, Hanna K, Lam, Alex K, Cho, Arthur, Rezek, Valerie, Wu, Nanping, Abril-Rodriguez, Gabriel, Rosser, Ethan W, Mittelman, Steven D, Hugo, Willy, Mehrling, Thomas, Bantia, Shanta, Ribas, Antoni, Donahue, Timothy R, Crooks, Gay M, Wu, Ting-Ting, Radu, Caius G
Published in The Journal of clinical investigation (15.08.2022)
Published in The Journal of clinical investigation (15.08.2022)
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Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair
Li, Shen, Yokota, Tomohiro, Wang, Ping, Ten Hoeve, Johanna, Ma, Feiyang, Le, Thuc M, Abt, Evan R, Zhou, Yonggang, Wu, Rimao, Nanthavongdouangsy, Maxine, Rodriguez, Abraham, Wang, Yijie, Lin, Yen-Ju, Muranaka, Hayato, Sharpley, Mark, Braddock, Demetrios T, MacRae, Vicky E, Banerjee, Utpal, Chiou, Pei-Yu, Seldin, Marcus, Huang, Dian, Teitell, Michael, Gertsman, Ilya, Jung, Michael, Bensinger, Steven J, Damoiseaux, Robert, Faull, Kym, Pellegrini, Matteo, Lusis, Aldons J, Graeber, Thomas G, Radu, Caius G, Deb, Arjun
Published in The Journal of clinical investigation (18.01.2022)
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AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis
Guo, Deliang, Hildebrandt, Isabel J, Prins, Robert M, Soto, Horacio, Mazzotta, Mary M, Dang, Julie, Czernin, Johannes, Shyy, John Y.-J, Watson, Andrew D, Phelps, Michael, Radu, Caius G, Cloughesy, Timothy F, Mischel, Paul S
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2009)
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Migration to Apoptotic “Find-me” Signals Is Mediated via the Phagocyte Receptor G2A
Peter, Christoph, Waibel, Michaela, Radu, Caius G., Yang, Li V., Witte, Owen N., Schulze-Osthoff, Klaus, Wesselborg, Sebastian, Lauber, Kirsten
Published in The Journal of biological chemistry (29.02.2008)
Published in The Journal of biological chemistry (29.02.2008)
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[18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity
Kim, Woosuk, Le, Thuc M., Wei, Liu, Poddar, Soumya, Bazzy, Jimmy, Wang, Xuemeng, Uong, Nhu T., Abt, Evan R., Capri, Joseph R., Austin, Wayne R., Van Valkenburgh, Juno S., Steele, Dalton, Gipson, Raymond M., Slavik, Roger, Cabebe, Anthony E., Taechariyakul, Thotsophon, Yaghoubi, Shahriar S., Lee, Jason T., Sadeghi, Saman, Lavie, Arnon, Faull, Kym F., Witte, Owen N., Donahue, Timothy R., Phelps, Michael E., Herschman, Harvey R., Herrmann, Ken, Czernin, Johannes, Radu, Caius G.
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2016)
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ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways
Le, Thuc M., Poddar, Soumya, Capri, Joseph R., Abt, Evan R., Kim, Woosuk, Wei, Liu, Uong, Nhu T., Cheng, Chloe M., Braas, Daniel, Nikanjam, Mina, Rix, Peter, Merkurjev, Daria, Zaretsky, Jesse, Kornblum, Harley I., Ribas, Antoni, Herschman, Harvey R., Whitelegge, Julian, Faull, Kym F., Donahue, Timothy R., Czernin, Johannes, Radu, Caius G.
Published in Nature communications (14.08.2017)
Published in Nature communications (14.08.2017)
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Positron emission tomography reporter genes and reporter probes: gene and cell therapy applications
Yaghoubi, Shahriar S, Campbell, Dean O, Radu, Caius G, Czernin, Johannes
Published in Theranostics (01.01.2012)
Published in Theranostics (01.01.2012)
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Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancer
Lückerath, Katharina, Wei, Liu, Fendler, Wolfgang P., Evans-Axelsson, Susan, Stuparu, Andreea D., Slavik, Roger, Mona, Christine E., Calais, Jeremie, Rettig, Matthew, Reiter, Robert E., Herrmann, Ken, Radu, Caius G., Czernin, Johannes, Eiber, Matthias
Published in EJNMMI research (29.10.2018)
Published in EJNMMI research (29.10.2018)
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Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells
Vatakis, Dimitrios N, Koya, Richard C, Nixon, Christopher C, Wei, Liu, Kim, Sohn G, Avancena, Patricia, Bristol, Gregory, Baltimore, David, Kohn, Donald B, Ribas, Antoni, Radu, Caius G, Galic, Zoran, Zack, Jerome A
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2011)
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Targeted noninvasive imaging of the innate immune response
McCracken, Melissa N., Radu, Caius G.
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2015)
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Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance
Bunimovich, Yuri L, Nair-Gill, Evan, Riedinger, Mireille, McCracken, Melissa N, Cheng, Donghui, McLaughlin, Jami, Radu, Caius G, Witte, Owen N
Published in PloS one (07.08.2014)
Published in PloS one (07.08.2014)
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Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses
Koya, Richard C., Mok, Stephen, Comin-Anduix, Begoña, Chodon, Thinle, Radu, Caius G., Nishimura, Michael I., Witte, Owen N., Ribas, Antoni
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
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Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A
Yang, Li V., Radu, Caius G., Wang, Li, Riedinger, Mireille, Witte, Owen N.
Published in Blood (01.02.2005)
Published in Blood (01.02.2005)
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Differential Proton Sensitivity of Related G Protein-Coupled Receptors T Cell Death-Associated Gene 8 and G2A Expressed in Immune Cells
Radu, Caius G., Nijagal, Amar, McLaughlin, Jami, Wang, Li, Witte, Owen N.
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2005)
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