Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis
Garcia, Samuel, Hartkamp, Linda M, Malvar-Fernandez, B, van Es, Inge E, Lin, Haishan, Wong, Justin, Long, Li, Zanghi, James A, Rankin, Andrew L, Masteller, Emma L, Wong, Brian R, Radstake, Timothy R D J, Tak, Paul P, Reedquist, Kris A
Published in Arthritis research & therapy (31.03.2016)
Published in Arthritis research & therapy (31.03.2016)
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Control of cytokine mRNA degradation by the histone deacetylase inhibitor ITF2357 in rheumatoid arthritis fibroblast-like synoviocytes: beyond transcriptional regulation
Angiolilli, Chiara, Kabala, Pawel A, Grabiec, Aleksander M, Rossato, Marzia, Lai, Wi S, Fossati, Gianluca, Mascagni, Paolo, Steinkühler, Christian, Blackshear, Perry J, Reedquist, Kris A, Baeten, Dominique L, Radstake, Timothy R D J
Published in Arthritis research & therapy (20.07.2018)
Published in Arthritis research & therapy (20.07.2018)
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Soluble immune complexes shift the TLR-induced cytokine production of distinct polarized human macrophage subsets towards IL-10
Ambarus, Carmen A, Santegoets, Kim C M, van Bon, Lenny, Wenink, Mark H, Tak, Paul P, Radstake, Timothy R D J, Baeten, Dominique L P
Published in PloS one (26.04.2012)
Published in PloS one (26.04.2012)
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Earliest Phase of Systemic Sclerosis Typified by Increased Levels of Inflammatory Proteins in the Serum
Cossu, Marta, Bon, Lenny, Preti, Carlo, Rossato, Marzia, Beretta, Lorenzo, Radstake, Timothy R. D. J.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2017)
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Characterization of Long Non-Coding RNAs in Systemic Sclerosis Monocytes: A Potential Role for PSMB8-AS1 in Altered Cytokine Secretion
Servaas, Nila H, Mariotti, Barbara, van der Kroef, Maarten, Wichers, Catharina G K, Pandit, Aridaman, Bazzoni, Flavia, Radstake, Timothy R D J, Rossato, Marzia
Published in International journal of molecular sciences (22.04.2021)
Published in International journal of molecular sciences (22.04.2021)
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Increased frequencies of circulating CXCL10-, CXCL8- and CCL4-producing monocytes and Siglec-3-expressing myeloid dendritic cells in systemic sclerosis patients
Carvalheiro, Tiago, Horta, Sara, van Roon, Joel A. G., Santiago, Mariana, Salvador, Maria J., Trindade, Hélder, Radstake, Timothy R. D. J., da Silva, José A. P., Paiva, Artur
Published in Inflammation research (01.02.2018)
Published in Inflammation research (01.02.2018)
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Identification of Small Heat Shock Protein B8 (HSP22) as a Novel TLR4 Ligand and Potential Involvement in the Pathogenesis of Rheumatoid Arthritis
Roelofs, Mieke F, Boelens, Wilbert C, Joosten, Leo A. B, Abdollahi-Roodsaz, Shahla, Geurts, Jeroen, Wunderink, Liza U, Schreurs, B. Willem, van den Berg, Wim B, Radstake, Timothy R. D. J
Published in Journal of Immunology (01.06.2006)
Published in Journal of Immunology (01.06.2006)
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Novel Association in Chromosome 4q27 Region with Rheumatoid Arthritis and Confirmation of Type 1 Diabetes Point to a General Risk Locus for Autoimmune Diseases
Zhernakova, Alexandra, Alizadeh, Behrooz Z., Bevova, Marianna, van Leeuwen, Miek A., Coenen, Marieke J.H., Franke, Barbara, Franke, Lude, Posthumus, Marcel D., van Heel, David A., van der Steege, Gerrit, Radstake, Timothy R.D.J., Barrera, Pilar, Roep, Bart O., Koeleman, Bobby P.C., Wijmenga, Cisca
Published in American journal of human genetics (01.12.2007)
Published in American journal of human genetics (01.12.2007)
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Multiomics and Machine Learning Accurately Predict Clinical Response to Adalimumab and Etanercept Therapy in Patients With Rheumatoid Arthritis
Tao, Weiyang, Concepcion, Arno N., Vianen, Marieke, Marijnissen, Anne C. A., Lafeber, Floris P. G. J., Radstake, Timothy R. D. J., Pandit, Aridaman
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2021)
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EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors
Kostine, Marie, Finckh, Axel, Bingham, Clifton O, Visser, Karen, Leipe, Jan, Schulze-Koops, Hendrik, Choy, Ernest H, Benesova, Karolina, Radstake, Timothy R D J, Cope, Andrew P, Lambotte, Olivier, Gottenberg, Jacques-Eric, Allenbach, Yves, Visser, Marianne, Rusthoven, Cindy, Thomasen, Lone, Jamal, Shahin, Marabelle, Aurélien, Larkin, James, Haanen, John B A G, Calabrese, Leonard H, Mariette, Xavier, Schaeverbeke, Thierry
Published in Annals of the rheumatic diseases (01.01.2021)
Published in Annals of the rheumatic diseases (01.01.2021)
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Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis
Toonen, Erik J M, Gilissen, Christian, Franke, Barbara, Kievit, Wietske, Eijsbouts, Agnes M, den Broeder, Alfons A, van Reijmersdal, Simon V, Veltman, Joris A, Scheffer, Hans, Radstake, Timothy R D J, van Riel, Piet L C M, Barrera, Pilar, Coenen, Marieke J H
Published in PloS one (21.03.2012)
Published in PloS one (21.03.2012)
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TLR2 Promotes Th2/Th17 Responses via TLR4 and TLR7/8 by Abrogating the Type I IFN Amplification Loop
Wenink, Mark H, Santegoets, Kim C. M, Broen, Jacobus C. A, van Bon, Lenny, Abdollahi-Roodsaz, Shahla, Popa, Calin, Huijbens, Richard, Remijn, Thijs, Lubberts, Erik, van Riel, Piet L. C. M, van den Berg, Wim B, Radstake, Timothy R. D. J
Published in The Journal of immunology (1950) (01.12.2009)
Published in The Journal of immunology (1950) (01.12.2009)
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The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade
Hillen, Maarten R, Hartgring, Sarita A Y, Willis, Cynthia R, Radstake, Timothy R D J, Hack, Cornelis E, Lafeber, Floris P J G, van Roon, Joel A G
Published in PloS one (25.06.2015)
Published in PloS one (25.06.2015)
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EULAR points to consider for the use of big data in rheumatic and musculoskeletal diseases
Gossec, Laure, Kedra, Joanna, Servy, Hervé, Pandit, Aridaman, Stones, Simon, Berenbaum, Francis, Finckh, Axel, Baraliakos, Xenofon, Stamm, Tanja A, Gomez-Cabrero, David, Pristipino, Christian, Choquet, Remy, Burmester, Gerd R, Radstake, Timothy R D J
Published in Annals of the rheumatic diseases (01.01.2020)
Published in Annals of the rheumatic diseases (01.01.2020)
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Conference Proceeding
Morphea and Eosinophilic Fasciitis: An Update
Mertens, Jorre S., Seyger, Marieke M. B., Thurlings, Rogier M., Radstake, Timothy R. D. J., de Jong, Elke M. G. J.
Published in American journal of clinical dermatology (01.08.2017)
Published in American journal of clinical dermatology (01.08.2017)
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Neutrophil extracellular trap release is associated with antinuclear antibodies in systemic lupus erythematosus and anti-phospholipid syndrome
van der Linden, Maarten, van den Hoogen, Lucas L, Westerlaken, Geertje H A, Fritsch-Stork, Ruth D E, van Roon, Joël A G, Radstake, Timothy R D J, Meyaard, Linde
Published in Rheumatology (Oxford, England) (01.07.2018)
Published in Rheumatology (Oxford, England) (01.07.2018)
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