Search Results - "Rachid El-Kouhen" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel Transient Receptor Potential Type V1 Receptor Antagonist, Relieves Pathophysiological Pain Associated with Inflammation and Tissue Injury in Rats

A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel Transient Receptor Potential Type V1 Receptor Antagonist, Relieves Pathophysiological Pain Associated with Inflammation and Tissue Injury in Rats

by Honore, Prisca, Wismer, Carol T, Mikusa, Joe, Zhu, Chang Z, Zhong, Chengmin, Gauvin, Donna M, Gomtsyan, Arthur, El Kouhen, Rachid, Lee, Chih-Hung, Marsh, Kennan, Sullivan, James P, Faltynek, Connie R, Jarvis, Michael F
Published in The Journal of pharmacology and experimental therapeutics (01.07.2005)

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Journal Article

High content screen microscopy analysis of Aβ1–42 -induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands

High content screen microscopy analysis of Aβ1–42 -induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands

by Hu, Min, Schurdak, Mark E, Puttfarcken, Pamela S, El Kouhen, Rachid, Gopalakrishnan, Murali, Li, Jinhe
Published in Brain research (04.09.2007)

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Journal Article

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

by Faghih, Ramin, Gopalakrishnan, Sujatha M, Gronlien, Jens Halvard, Malysz, John, Briggs, Clark A, Wetterstrand, Caroline, Ween, Hilde, Curtis, Michael P, Sarris, Kathy A, Gfesser, Gregory A, El-Kouhen, Rachid, Robb, Holly M, Radek, Richard J, Marsh, Kennan C, Bunnelle, William H, Gopalakrishnan, Murali
Published in Journal of medicinal chemistry (28.05.2009)

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Journal Article

A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel and Selective Transient Receptor Potential Type V1 Receptor Antagonist, Blocks Channel Activation by Vanilloids, Heat, and Acid

A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel and Selective Transient Receptor Potential Type V1 Receptor Antagonist, Blocks Channel Activation by Vanilloids, Heat, and Acid

by El Kouhen, Rachid, Surowy, Carol S, Bianchi, Bruce R, Neelands, Torben R, McDonald, Heath A, Niforatos, Wende, Gomtsyan, Arthur, Lee, Chih-Hung, Honore, Prisca, Sullivan, James P, Jarvis, Michael F, Faltynek, Connie R
Published in The Journal of pharmacology and experimental therapeutics (01.07.2005)

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Journal Article

Capsaicin Infused Into the PAG Affects Rat Tail Flick Responses to Noxious Heat and Alters Neuronal Firing in the RVM

Capsaicin Infused Into the PAG Affects Rat Tail Flick Responses to Noxious Heat and Alters Neuronal Firing in the RVM

by McGaraughty, Steve, Chu, Katharine L, Bitner, Robert S, Martino, Brenda, Kouhen, Rachid El, Han, Ping, Nikkel, Arthur L, Burgard, Edward C, Faltynek, Connie R, Jarvis, Michael F
Published in Journal of neurophysiology (01.10.2003)

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Journal Article

(R)-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) Blocks Polymodal Activation of Transient Receptor Potential Vanilloid 1 Receptors in Vitro and Heat-Evoked Firing of Spinal Dorsal Horn Neurons in Vivo

(R)-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) Blocks Polymodal Activation of Transient Receptor Potential Vanilloid 1 Receptors in Vitro and Heat-Evoked Firing of Spinal Dorsal Horn Neurons in Vivo

by Surowy, Carol S, Neelands, Torben R, Bianchi, Bruce R, McGaraughty, Steve, El Kouhen, Rachid, Han, Ping, Chu, Katharine L, McDonald, Heath A, Vos, Melissa, Niforatos, Wende, Bayburt, Erol K, Gomtsyan, Arthur, Lee, Chih-Hung, Honore, Prisca, Sullivan, James P, Jarvis, Michael F, Faltynek, Connie R
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)

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Journal Article

Capsaicin causes protein synthesis inhibition and microtubule disassembly through TRPV1 activities both on the plasma membrane and intracellular membranes

Capsaicin causes protein synthesis inhibition and microtubule disassembly through TRPV1 activities both on the plasma membrane and intracellular membranes

by Han, Ping, McDonald, Heath A., Bianchi, Bruce R., Kouhen, Rachid El, Vos, Melissa H., Jarvis, Michael F., Faltynek, Connie R., Moreland, Robert B.
Published in Biochemical pharmacology (15.05.2007)

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Journal Article

Modulation of human TRPV1 receptor activity by extracellular protons and host cell expression system

Modulation of human TRPV1 receptor activity by extracellular protons and host cell expression system

by Bianchi, Bruce R., Lee, Chih-Hung, Jarvis, Michael F., El Kouhen, Rachid, Moreland, Robert B., Faltynek, Connie R., Puttfarcken, Pamela S.
Published in European journal of pharmacology (10.05.2006)

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Journal Article

[3H]A-778317 [1-((R)-5-tert-Butyl-indan-1-yl)-3-isoquinolin-5-yl-urea]: a Novel, Stereoselective, High-Affinity Antagonist Is a Useful Radioligand for the Human Transient Receptor Potential Vanilloid-1 (TRPV1) Receptor

[3H]A-778317 [1-((R)-5-tert-Butyl-indan-1-yl)-3-isoquinolin-5-yl-urea]: a Novel, Stereoselective, High-Affinity Antagonist Is a Useful Radioligand for the Human Transient Receptor Potential Vanilloid-1 (TRPV1) Receptor

by Bianchi, Bruce R, El Kouhen, Rachid, Neelands, Torben R, Lee, Chih-Hung, Gomtsyan, Arthur, Raja, Shirish N, Vaidyanathan, Sriajan N, Surber, Bruce, McDonald, Heath A, Surowy, Carol S, Faltynek, Connie R, Moreland, Robert B, Jarvis, Michael F, Puttfarcken, Pamela S
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)

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Journal Article

Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity α4β2 subunit combination

by Anderson, David J., Malysz, John, Grønlien, Jens Halvard, El Kouhen, Rachid, Håkerud, Monika, Wetterstrand, Caroline, Briggs, Clark A., Gopalakrishnan, Murali
Published in Biochemical pharmacology (01.10.2009)

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Journal Article Conference Proceeding

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the alpha 7 Nicotinic Acetylcholine Receptor

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the alpha 7 Nicotinic Acetylcholine Receptor

by Faghih, Ramin, Gopalakrishnan, Sujatha M., Gronlien, Jens Halvard, Malysz, John, Briggs, Clark A., Wetterstrand, Caroline, Ween, Hilde, Curtis, Michael P., Sarris, Kathy A., Gfesser, Gregory A., El-Kouhen, Rachid, Robb, Holly M., Radek, Richard J., Marsh, Kennan C., Bunnelle, William H., Gopalakrishnan, Murali
Published in Journal of medicinal chemistry (28.05.2009)

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Journal Article

Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity alpha 4 beta 2 subunit combination

by Anderson, David J, Malysz, John, Groenlien, Jens Halvard, El Kouhen, Rachid, Haakerud, Monika, Wetterstrand, Caroline, Briggs, Clark A, Gopalakrishnan, Murali
Published in Biochemical pharmacology (01.10.2009)

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Journal Article

In vitro pharmacological characterization of ABT-779, a novel positive allosteric modulator of α7 nAChRs

In vitro pharmacological characterization of ABT-779, a novel positive allosteric modulator of α7 nAChRs

by Malysz, John, Gronlien, Jens Halvard, Briggs, Clark A., Anderson, David J., El-Kouhen, Rachid, Drescher, Karla, Ween, Hilde, Thorin-Hagene, Kristen, Mortell, Kathleen, Lee, Chih-Hung, Gopalakrishnan, Murali
Published in Biochemical pharmacology (01.10.2011)

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Journal Article

Binding of [ 3H]A-778317 to native transient receptor potential vanilloid-1 (TRPV1) channels in rat dorsal root ganglia and spinal cord

Binding of [ 3H]A-778317 to native transient receptor potential vanilloid-1 (TRPV1) channels in rat dorsal root ganglia and spinal cord

by Bianchi, Bruce R., El Kouhen, Rachid, Chen, Jun, Puttfarcken, Pamela S.
Published in European journal of pharmacology (10.05.2010)

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Journal Article

High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands

High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands

by Hu, Min, Schurdak, Mark E, Puttfarcken, Pamela S, El Kouhen, Rachid, Gopalakrishnan, Murali, Li, Jinhe
Published in Brain research (02.06.2007)

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Journal Article

High content screen microscopy analysis of Aβ 1–42-induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands

High content screen microscopy analysis of Aβ 1–42-induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands

by Hu, Min, Schurdak, Mark E., Puttfarcken, Pamela S., El Kouhen, Rachid, Gopalakrishnan, Murali, Li, Jinhe
Published in Brain research (2007)

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Journal Article

Receptor density and recycling affect the rate of agonist-induced desensitization of mu-opioid receptor

Receptor density and recycling affect the rate of agonist-induced desensitization of mu-opioid receptor

by Law, P Y, Erickson, L J, El-Kouhen, R, Dicker, L, Solberg, J, Wang, W, Miller, E, Burd, A L, Loh, H H
Published in Molecular pharmacology (01.08.2000)

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Journal Article

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1 H -pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1 H -pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

by Faghih, Ramin, Gopalakrishnan, Sujatha M., Gronlien, Jens Halvard, Malysz, John, Briggs, Clark A., Wetterstrand, Caroline, Ween, Hilde, Curtis, Michael P., Sarris, Kathy A., Gfesser, Gregory A., El-Kouhen, Rachid, Robb, Holly M., Radek, Richard J., Marsh, Kennan C., Bunnelle, William H., Gopalakrishnan, Murali
Published in Journal of medicinal chemistry (28.05.2009)

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Journal Article

Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity alpha4beta2 subunit combination

by Anderson, David J, Malysz, John, Grønlien, Jens Halvard, El Kouhen, Rachid, Håkerud, Monika, Wetterstrand, Caroline, Briggs, Clark A, Gopalakrishnan, Murali
Published in Biochemical pharmacology (01.10.2009)

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Journal Article

The absence of a direct correlation between the loss of [D-Ala2, MePhe4,Gly5-ol]Enkephalin inhibition of adenylyl cyclase activity and agonist-induced mu-opioid receptor phosphorylation

The absence of a direct correlation between the loss of [D-Ala2, MePhe4,Gly5-ol]Enkephalin inhibition of adenylyl cyclase activity and agonist-induced mu-opioid receptor phosphorylation

by El Kouhen, R, Kouhen, O M, Law, P Y, Loh, H H
Published in The Journal of biological chemistry (02.04.1999)

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Journal Article