Functional heterogeneity and heritability in CHO cell populations
Davies, Sarah L., Lovelady, Clare S., Grainger, Rhian K., Racher, Andrew J., Young, Robert J., James, David C.
Published in Biotechnology and bioengineering (01.01.2013)
Published in Biotechnology and bioengineering (01.01.2013)
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Journal Article
Cell line-specific control of recombinant monoclonal antibody production by CHO cells
O'Callaghan, Peter M, McLeod, Jane, Pybus, Leon P, Lovelady, Clare S, Wilkinson, Stephen J, Racher, Andrew J, Porter, Alison, James, David C
Published in Biotechnology and bioengineering (15.08.2010)
Published in Biotechnology and bioengineering (15.08.2010)
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Journal Article
Diversity in host clone performance within a Chinese hamster ovary cell line
O'Callaghan, Peter M., Berthelot, Maud E., Young, Robert J., Graham, James W.A., Racher, Andrew J., Aldana, Dulce
Published in Biotechnology progress (01.09.2015)
Published in Biotechnology progress (01.09.2015)
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A proline metabolism selection system and its application to the engineering of lipid biosynthesis in Chinese hamster ovary cells
Budge, James D., Roobol, Joanne, Singh, Gurdeep, Mozzanino, Théo, Knight, Tanya J., Povey, Jane, Dean, Andrew, Turner, Sarah J., Jaques, Colin M., Young, Robert J., Racher, Andrew J., Smales, C. Mark
Published in Metabolic engineering communications (01.12.2021)
Published in Metabolic engineering communications (01.12.2021)
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Journal Article
Impact of gene vector design on the control of recombinant monoclonal antibody production by chinese hamster ovary cells
Davies, Sarah L., O'Callaghan, Peter M., McLeod, Jane, Pybus, Leon P., Sung, Yun Hee, Rance, James, Wilkinson, Stephen J., Racher, Andrew J., Young, Robert J., James, David C.
Published in Biotechnology progress (01.11.2011)
Published in Biotechnology progress (01.11.2011)
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Journal Article
Data for engineering lipid metabolism of Chinese hamster ovary (CHO) cells for enhanced recombinant protein production
Budge, James D., Knight, Tanya J., Povey, Jane, Roobol, Joanne, Brown, Ian R., Singh, Gurdeep, Dean, Andrew, Turner, Sarah, Jaques, Colin M., Young, Robert J., Racher, Andrew J., Smales, C Mark
Published in Data in brief (01.04.2020)
Published in Data in brief (01.04.2020)
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Journal Article
An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer
McLeod, Jane, O'Callaghan, Peter M., Pybus, Leon P., Wilkinson, Stephen J., Root, Tracy, Racher, Andrew J., James, David C.
Published in Biotechnology and bioengineering (01.09.2011)
Published in Biotechnology and bioengineering (01.09.2011)
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Intact-Cell MALDI-ToF Mass Spectrometry for the Authentication of Drug-Adapted Cancer Cell Lines
Povey, Jane F, Saintas, Emily, Aderemi, Adewale V, Rothweiler, Florian, Zehner, Richard, Dirks, Wilhelm G, Cinatl, Jr, Jindrich, Racher, Andrew J, Wass, Mark N, Smales, C Mark, Michaelis, Martin
Published in Cells (Basel, Switzerland) (02.10.2019)
Published in Cells (Basel, Switzerland) (02.10.2019)
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Improving the accuracy of flux balance analysis through the implementation of carbon availability constraints for intracellular reactions
Lularevic, Maximilian, Racher, Andrew J., Jaques, Colin, Kiparissides, Alexandros
Published in Biotechnology and bioengineering (01.09.2019)
Published in Biotechnology and bioengineering (01.09.2019)
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Journal Article
Metabolic Rates, Growth Phase, and mRNA Levels Influence Cell-Specific Antibody Production Levels from In Vitro-Cultured Mammalian Cells at Sub-Physiological Temperatures
Marchant, Rosalyn J., Al-Fageeh, Mohamed B., Underhill, Michele F., Racher, Andrew J., Smales, C. Mark
Published in Molecular biotechnology (01.05.2008)
Published in Molecular biotechnology (01.05.2008)
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Journal Article
Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production
Budge, James D., Knight, Tanya J., Povey, Jane, Roobol, Joanne, Brown, Ian R., Singh, Gurdeep, Dean, Andrew, Turner, Sarah, Jaques, Colin M., Young, Robert J., Racher, Andrew J., Smales, C. Mark
Published in Metabolic engineering (01.01.2020)
Published in Metabolic engineering (01.01.2020)
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Journal Article
Directed evolution of biomass intensive CHO cells by adaptation to sub-physiological temperature
Syddall, Katie L, Fernandez-Martell, Alejandro, Cartwright, Joseph F, Alexandru-Crivac, Cristina N, Hodgson, Adam, Racher, Andrew J, Young, Robert J, James, David C
Published in Metabolic engineering (01.01.2024)
Published in Metabolic engineering (01.01.2024)
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Rapid high-throughput characterisation, classification and selection of recombinant mammalian cell line phenotypes using intact cell MALDI-ToF mass spectrometry fingerprinting and PLS-DA modelling
Povey, Jane F., O’Malley, Christopher J., Root, Tracy, Martin, Elaine B., Montague, Gary A., Feary, Marc, Trim, Carol, Lang, Dietmar A., Alldread, Richard, Racher, Andrew J., Smales, C. Mark
Published in Journal of biotechnology (20.08.2014)
Published in Journal of biotechnology (20.08.2014)
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