A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II
Sonoda, Hiroyuki, Morimoto, Hideto, Yoden, Eiji, Koshimura, Yuri, Kinoshita, Masafumi, Golovina, Galina, Takagi, Haruna, Yamamoto, Ryuji, Minami, Kohtaro, Mizoguchi, Akira, Tachibana, Katsuhiko, Hirato, Tohru, Takahashi, Kenichi
Published in Molecular therapy (02.05.2018)
Published in Molecular therapy (02.05.2018)
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Evaluation of cerebrospinal fluid heparan sulfate as a biomarker of neuropathology in a murine model of mucopolysaccharidosis type II using high-sensitivity LC/MS/MS
Tanaka, Noboru, Kida, Sachiho, Kinoshita, Masafumi, Morimoto, Hideto, Shibasaki, Tadao, Tachibana, Katsuhiko, Yamamoto, Ryuji
Published in Molecular genetics and metabolism (01.09.2018)
Published in Molecular genetics and metabolism (01.09.2018)
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Clearance of heparan sulfate in the brain prevents neurodegeneration and neurocognitive impairment in MPS II mice
Morimoto, Hideto, Kida, Sachiho, Yoden, Eiji, Kinoshita, Masafumi, Tanaka, Noboru, Yamamoto, Ryuji, Koshimura, Yuri, Takagi, Haruna, Takahashi, Kenichi, Hirato, Tohru, Minami, Kohtaro, Sonoda, Hiroyuki
Published in Molecular therapy (05.05.2021)
Published in Molecular therapy (05.05.2021)
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Potential for Drug Repositioning of Midazolam as an Inhibitor of Inflammatory Bone Resorption
Harigaya, Hiroko, Chiba-Ohkuma, Risako, Karakida, Takeo, Yamamoto, Ryuji, Fujii-Abe, Keiko, Kawahara, Hiroshi, Yamakoshi, Yasuo
Published in International journal of molecular sciences (01.07.2024)
Published in International journal of molecular sciences (01.07.2024)
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Pathogenic Roles of Heparan Sulfate and Its Use as a Biomarker in Mucopolysaccharidoses
Minami, Kohtaro, Morimoto, Hideto, Morioka, Hiroki, Imakiire, Atsushi, Kinoshita, Masafumi, Yamamoto, Ryuji, Hirato, Tohru, Sonoda, Hiroyuki
Published in International journal of molecular sciences (03.10.2022)
Published in International journal of molecular sciences (03.10.2022)
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Effects of Er:YAG and Diode Laser Irradiation on Dental Pulp Cells and Tissues
Yamakawa, Shunjiro, Niwa, Takahiko, Karakida, Takeo, Kobayashi, Kazuyuki, Yamamoto, Ryuji, Chiba, Risako, Yamakoshi, Yasuo, Hosoya, Noriyasu
Published in International journal of molecular sciences (17.08.2018)
Published in International journal of molecular sciences (17.08.2018)
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Dose-dependent effects of a brain-penetrating iduronate-2-sulfatase on neurobehavioral impairments in mucopolysaccharidosis II mice
Morimoto, Hideto, Morioka, Hiroki, Imakiire, Atsushi, Yamamoto, Ryuji, Hirato, Tohru, Sonoda, Hiroyuki, Minami, Kohtaro
Published in Molecular therapy. Methods & clinical development (09.06.2022)
Published in Molecular therapy. Methods & clinical development (09.06.2022)
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Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II
Yamamoto, Ryuji, Yoden, Eiji, Tanaka, Noboru, Kinoshita, Masafumi, Imakiire, Atsushi, Hirato, Tohru, Minami, Kohtaro
Published in Molecular genetics and metabolism reports (01.06.2021)
Published in Molecular genetics and metabolism reports (01.06.2021)
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Physicochemical and biological evaluation of JR-131 as a biosimilar to a long-acting erythropoiesis-stimulating agent darbepoetin alfa
Tani, Junya, Ito, Yae, Tatemichi, Satoshi, Yamakami, Makoto, Fukui, Tsuyoshi, Hatano, Yukichi, Kakimoto, Shinji, Kotani, Ayaka, Sugimura, Atsushi, Mihara, Kazutoshi, Yamamoto, Ryuji, Tanaka, Noboru, Minami, Kohtaro, Takahashi, Kenichi, Hirato, Tohru
Published in PloS one (17.04.2020)
Published in PloS one (17.04.2020)
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Effect of Nerve Growth Factor on Osseointegration of Titanium Implants in Type 2 Diabetic Rats
Zhang, Jing, Shirai, Mai, Yamamoto, Ryuji, Yamakoshi, Yasuo, Oida, Shinichiro, Ohkubo, Chikahiro, Zeng, Jianyu
Published in The International journal of oral and maxillofacial implants (01.09.2016)
Published in The International journal of oral and maxillofacial implants (01.09.2016)
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Potential for Drug Repositioning of Midazolam for Dentin Regeneration
Karakida, Takeo, Onuma, Kazuo, Saito, Mari M, Yamamoto, Ryuji, Chiba, Toshie, Chiba, Risako, Hidaka, Yukihiko, Fujii-Abe, Keiko, Kawahara, Hiroshi, Yamakoshi, Yasuo
Published in International journal of molecular sciences (04.02.2019)
Published in International journal of molecular sciences (04.02.2019)
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Non-clinical evaluation of JR-051 as a biosimilar to agalsidase beta for the treatment of Fabry disease
Morimoto, Hideto, Ito, Yae, Yoden, Eiji, Horie, Masato, Tanaka, Noboru, Komurasaki, Yoshikazu, Yamamoto, Ryuji, Mihara, Kazutoshi, Minami, Kohtaro, Hirato, Tohru
Published in Molecular genetics and metabolism (01.09.2018)
Published in Molecular genetics and metabolism (01.09.2018)
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Repurposing MDZ as a tool for tissue regeneration in dental cells
Yamakoshi, Yasuo, Chiba-Ohkuma, Risako, Hidaka, Yukihiko, Onuma, Kazuo, Yamamoto, Ryuji, Saito, Mari M., Karakida, Takeo
Published in Journal of oral biosciences (01.03.2022)
Published in Journal of oral biosciences (01.03.2022)
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Antitubercular Activity of Disulfiram, an Antialcoholism Drug, against Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Isolates
HORITA, Yasuhiro, TAKII, Takemasa, MAKINO, Toshiaki, MIZUKAMI, Hajime, HASEGAWA, Tomohiro, YAMAMOTO, Ryuji, ONOZAKI, Kikuo, YAGI, Tetsuya, OGAWA, Kenji, FUJIWARA, Nagatoshi, INAGAKI, Emi, KREMER, Laurent, SATO, Yasuo, KUROISHI, Ryuji, LEE, Yoosa
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
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Enzyme replacement with transferrin receptor-targeted α-L-iduronidase rescues brain pathology in mucopolysaccharidosis I mice
Kida, Sachiho, Koshimura, Yuri, Yoden, Eiji, Yoshioka, Aya, Morimoto, Hideto, Imakiire, Atsushi, Tanaka, Noboru, Tanaka, Satowa, Mori, Ayaka, Ito, Jun, Inoue, Asuka, Yamamoto, Ryuji, Minami, Kohtaro, Hirato, Tohru, Takahashi, Kenichi, Sonoda, Hiroyuki
Published in Molecular therapy. Methods & clinical development (08.06.2023)
Published in Molecular therapy. Methods & clinical development (08.06.2023)
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Characterization of bioactive substances involved in the induction of bone augmentation using demineralized bone sheets
Saito, Haruka, Chiba-Ohkuma, Risako, Yamakoshi, Yasuo, Karakida, Takeo, Yamamoto, Ryuji, Shirai, Mai, Ohkubo, Chikahiro
Published in International journal of implant dentistry (01.11.2022)
Published in International journal of implant dentistry (01.11.2022)
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Development and Characterization of Alkaline Phosphatase-Positive Human Umbilical Cord Perivascular Cells
Nonoyama, Shun, Karakida, Takeo, Chiba-Ohkuma, Risako, Yamamoto, Ryuji, Ujiie, Yuko, Nagano, Takatoshi, Yamakoshi, Yasuo, Gomi, Kazuhiro
Published in Cells (Basel, Switzerland) (04.11.2021)
Published in Cells (Basel, Switzerland) (04.11.2021)
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TGF-β and Physiological Root Resorption of Deciduous Teeth
Shimazaki, Emi, Karakida, Takeo, Yamamoto, Ryuji, Kobayashi, Saeko, Fukae, Makoto, Yamakoshi, Yasuo, Asada, Yoshinobu
Published in International journal of molecular sciences (27.12.2016)
Published in International journal of molecular sciences (27.12.2016)
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