Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy
Jang, Yoonjeong, Kim, Yoon-Sang, Wielgosz, Matthew M, Ferrara, Francesca, Ma, Zhijun, Condori, Jose, Palmer, Lance E, Zhao, Xiwen, Kang, Guolian, Rawlings, David J, Zhou, Sheng, Ryu, Byoung Y
Published in Gene therapy (01.12.2020)
Published in Gene therapy (01.12.2020)
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Audible blink in carotid-cavernous fistula
Ryu, Byoung U., Owji, Shahin, Pakravan, Mohammad, Charoenkijkajorn, Chaow, Lee, Andrew G.
Published in Canadian journal of ophthalmology (01.02.2023)
Published in Canadian journal of ophthalmology (01.02.2023)
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Genome editing of HBG1 and HBG2 to induce fetal hemoglobin
Métais, Jean-Yves, Doerfler, Phillip A., Mayuranathan, Thiyagaraj, Bauer, Daniel E., Fowler, Stephanie C., Hsieh, Matthew M., Katta, Varun, Keriwala, Sagar, Lazzarotto, Cicera R., Luk, Kevin, Neel, Michael D., Perry, S. Scott, Peters, Samuel T., Porter, Shaina N., Ryu, Byoung Y., Sharma, Akshay, Shea, Devlin, Tisdale, John F., Uchida, Naoya, Wolfe, Scot A., Woodard, Kaitly J., Wu, Yuxuan, Yao, Yu, Zeng, Jing, Pruett-Miller, Shondra, Tsai, Shengdar Q., Weiss, Mitchell J.
Published in Blood advances (12.11.2019)
Published in Blood advances (12.11.2019)
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Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors
Bandaranayake, Ashok D., Correnti, Colin, Ryu, Byoung Y., Brault, Michelle, Strong, Roland K., Rawlings, David J.
Published in Nucleic acids research (01.11.2011)
Published in Nucleic acids research (01.11.2011)
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In vivo CAR T-cell generation in nonhuman primates using lentiviral vectors displaying a multidomain fusion ligand
Nicolai, Christopher J., Parker, Maura H., Qin, Jim, Tang, Weiliang, Ulrich-Lewis, Justin T., Gottschalk, Rebecca J., Cooper, Sara E., Hernandez Lopez, Susana A., Parrilla, Don, Mangio, Richard S., Ericson, Nolan G., Brandes, Alissa H., Umuhoza, Saluwa, Michels, Kathryn R., McDonnell, Mollie M., Park, Lisa Y., Shin, Seungjin, Leung, Wai-Hang, Scharenberg, Andrew M., Kiem, Hans-Peter, Larson, Ryan P., Beitz, Laurie O., Ryu, Byoung Y.
Published in Blood (29.08.2024)
Published in Blood (29.08.2024)
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Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation
LeBlanc, Lucy, Lee, Bum-Kyu, Yu, Andy C, Kim, Mijeong, Kambhampati, Aparna V, Dupont, Shannon M, Seruggia, Davide, Ryu, Byoung U, Orkin, Stuart H, Kim, Jonghwan
Published in eLife (18.12.2018)
Published in eLife (18.12.2018)
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Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes
Ozog, Stosh, Timberlake, Nina D., Hermann, Kip, Garijo, Olivia, Haworth, Kevin G., Shi, Guoli, Glinkerman, Christopher M., Schefter, Lauren E., D'Souza, Saritha, Simpson, Elizabeth, Sghia-Hughes, Gabriella, Carillo, Raymond R., Boger, Dale L., Kiem, Hans-Peter, Slukvin, Igor, Ryu, Byoung Y., Sorrentino, Brian P., Adair, Jennifer E., Snyder, Scott A., Compton, Alex A., Torbett, Bruce E.
Published in Blood (17.10.2019)
Published in Blood (17.10.2019)
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Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media
Bauler, Matthew, Roberts, Jessica K., Wu, Chang-Chih, Fan, Baochang, Ferrara, Francesca, Yip, Bon Ham, Diao, Shiyong, Kim, Young-In, Moore, Jennifer, Zhou, Sheng, Wielgosz, Matthew M., Ryu, Byoung, Throm, Robert E.
Published in Molecular therapy. Methods & clinical development (12.06.2020)
Published in Molecular therapy. Methods & clinical development (12.06.2020)
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Coupling endonucleases with DNA end-processing enzymes to drive gene disruption
Certo, Michael T, Gwiazda, Kamila S, Kuhar, Ryan, Sather, Blythe, Curinga, Gabrielle, Mandt, Tyler, Brault, Michelle, Lambert, Abigail R, Baxter, Sarah K, Jacoby, Kyle, Ryu, Byoung Y, Kiem, Hans-Peter, Gouble, Agnes, Paques, Frederic, Rawlings, David J, Scharenberg, Andrew M
Published in Nature methods (01.10.2012)
Published in Nature methods (01.10.2012)
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Journal Article
Three Cases of Bilateral, Asymptomatic Orbital Varices
Ryu, Byoung U, Rao, Aishwarya V, Hasegawa, Naomi, Katz, Bradley J, Caskey, Eric, Seay, Meagan D, Harrie, Roger P, Adesina, Ore-Ofe O
Published in Journal of neuro-ophthalmology (01.06.2024)
Published in Journal of neuro-ophthalmology (01.06.2024)
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Preclinical proof of concept for VivoVec, a lentiviral-based platform for in vivo CAR T-cell engineering
Michels, Kathryn R, Sheih, Alyssa, Hernandez, Susana A, Brandes, Alissa H, Parrilla, Don, Irwin, Blythe, Perez, Anai M, Ting, Hung-An, Nicolai, Christopher J, Gervascio, Timothy, Shin, Seungjin, Pankau, Mark D, Muhonen, Mason, Freeman, Jessica, Gould, Sarah, Getto, Rich, Larson, Ryan P, Ryu, Byoung Y, Scharenberg, Andrew M, Sullivan, Alessandra M, Green, Shon
Published in Journal for immunotherapy of cancer (01.03.2023)
Published in Journal for immunotherapy of cancer (01.03.2023)
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Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome
Astrakhan, Alexander, Sather, Blythe D., Ryu, Byoung Y., Khim, Socheath, Singh, Swati, Humblet-Baron, Stephanie, Ochs, Hans D., Miao, Carol H., Rawlings, David J.
Published in Blood (10.05.2012)
Published in Blood (10.05.2012)
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Preclinical evaluation of efficacy and safety of an improved lentiviral vector for the treatment of β-thalassemia and sickle cell disease
Negre, Olivier, Bartholomae, Cynthia, Beuzard, Yves, Cavazzana, Marina, Christiansen, Lauryn, Courne, Céline, Deichmann, Annette, Denaro, Maria, de Dreuzy, Edouard, Finer, Mitchell, Fronza, Raffaele, Gillet-Legrand, Béatrix, Joubert, Christophe, Kutner, Robert, Leboulch, Philippe, Maouche, Leïla, Paulard, Anaïs, Pierciey, Francis J, Rothe, Michael, Ryu, Byoung, Schmidt, Manfred, von Kalle, Christof, Payen, Emmanuel, Veres, Gabor
Published in Current gene therapy (01.01.2015)
Published in Current gene therapy (01.01.2015)
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Journal Article
Tracking genome engineering outcome at individual DNA breakpoints
Certo, Michael T, Ryu, Byoung Y, Annis, James E, Garibov, Mikhail, Jarjour, Jordan, Rawlings, David J, Scharenberg, Andrew M
Published in Nature methods (01.08.2011)
Published in Nature methods (01.08.2011)
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Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector
Seymour, Brenda J., Singh, Swati, Certo, Hannah M., Sommer, Karen, Sather, Blythe D., Khim, Socheath, Clough, Courtnee, Hale, Malika, Pangallo, Joseph, Ryu, Byoung Y., Khan, Iram F., Adair, Jennifer E., Rawlings, David J.
Published in Molecular therapy. Methods & clinical development (12.03.2021)
Published in Molecular therapy. Methods & clinical development (12.03.2021)
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Journal Article
B cell–specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia
Kerns, Hannah M., Ryu, Byoung Y., Stirling, Brigid V., Sather, Blythe D., Astrakhan, Alexander, Humblet-Baron, Stephanie, Liggitt, Denny, Rawlings, David J.
Published in Blood (18.03.2010)
Published in Blood (18.03.2010)
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236 In vivo-generated TagCAR T cells inhibit solid tumor growth following treatment with bispecific small molecule TumorTags
Cambier, Cj, Coelho, Nanda, Sheih, Alyssa, Ting, Anna, Lynch, Kelsey, Mittelsteadt, Kristen, Zheng, Suilan, Teoh, Jeff, Low, Phillip, Larson, Ryan, Scharenberg, Andrew, Ryu, Byoung, Beitz, Laurie, Chu, Haiyan
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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The Art and Science of Selecting a CD123-Specific Chimeric Antigen Receptor for Clinical Testing
Riberdy, Janice M., Zhou, Sheng, Zheng, Fei, Kim, Young-In, Moore, Jennifer, Vaidya, Abishek, Throm, Robert E., Sykes, April, Sahr, Natasha, Bonifant, Challice L., Ryu, Byoung, Gottschalk, Stephen, Velasquez, Mireya Paulina
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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