Identification of a Selective, Non-Prostanoid EP2 Receptor Agonist for the Treatment of Glaucoma: Omidenepag and its Prodrug Omidenepag Isopropyl
Iwamura, Ryo, Tanaka, Masayuki, Okanari, Eiji, Kirihara, Tomoko, Odani-Kawabata, Noriko, Shams, Naveed, Yoneda, Kenji
Published in Journal of medicinal chemistry (09.08.2018)
Published in Journal of medicinal chemistry (09.08.2018)
Get full text
Journal Article
Downregulation of COL12A1 and COL13A1 by a selective EP2 receptor agonist, omidenepag, in human trabecular meshwork cells
Kumon, Masashi, Fuwa, Masahiro, Shimazaki, Atsushi, Odani-Kawabata, Noriko, Iwamura, Ryo, Yoneda, Kenji, Kato, Masatomo
Published in PloS one (11.01.2023)
Published in PloS one (11.01.2023)
Get full text
Journal Article
Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, on Aqueous Humor Dynamics in Laser-Induced Ocular Hypertensive Monkeys
Fuwa, Masahiro, Toris, Carol B, Fan, Shan, Taniguchi, Takazumi, Ichikawa, Masaki, Odani-Kawabata, Noriko, Iwamura, Ryo, Yoneda, Kenji, Matsugi, Takeshi, Shams, Naveed K, Zhang, Jin-Zhong
Published in Journal of ocular pharmacology and therapeutics (01.09.2018)
Published in Journal of ocular pharmacology and therapeutics (01.09.2018)
Get more information
Journal Article
Pharmacologic Characterization of Omidenepag Isopropyl, a Novel Selective EP2 Receptor Agonist, as an Ocular Hypotensive Agent
Kirihara, Tomoko, Taniguchi, Takazumi, Yamamura, Kenzo, Iwamura, Ryo, Yoneda, Kenji, Odani-Kawabata, Noriko, Shimazaki, Atsushi, Matsugi, Takeshi, Shams, Naveed, Zhang, Jin-Zhong
Published in Investigative ophthalmology & visual science (01.01.2018)
Published in Investigative ophthalmology & visual science (01.01.2018)
Get full text
Journal Article
Effects of the Selective EP2 Receptor Agonist Omidenepag on Adipocyte Differentiation in 3T3-L1 Cells
Yamamoto, Yasuko, Taniguchi, Takazumi, Inazumi, Tomoaki, Iwamura, Ryo, Yoneda, Kenji, Odani-Kawabata, Noriko, Matsugi, Takeshi, Sugimoto, Yukihiko, Shams, Naveed K
Published in Journal of ocular pharmacology and therapeutics (01.04.2020)
Published in Journal of ocular pharmacology and therapeutics (01.04.2020)
Get more information
Journal Article
Antiplatelet action of R‐99224, an active metabolite of a novel thienopyridine‐type Gi‐linked P2T antagonist, CS‐747
Sugidachi, Atsuhiro, Asai, Fumitoshi, Yoneda, Kenji, Iwamura, Ryo, Ogawa, Taketoshi, Otsuguro, Ken‐ichi, Koike, Hiroyuki
Published in British journal of pharmacology (01.01.2001)
Published in British journal of pharmacology (01.01.2001)
Get full text
Journal Article
Additive Intraocular Pressure-Lowering Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, Combined with Existing Antiglaucoma Agents in Conscious Ocular Normotensive Monkeys
Fuwa, Masahiro, Shimazaki, Atsushi, Odani-Kawabata, Noriko, Kirihara, Tomoko, Taniguchi, Takazumi, Iwamura, Ryo, Yoneda, Kenji, Kato, Masatomo, Morishima, Kenji, Shams, Naveed K
Published in Journal of ocular pharmacology and therapeutics (01.05.2021)
Published in Journal of ocular pharmacology and therapeutics (01.05.2021)
Get more information
Journal Article
The Antiglaucoma Agent and EP2 Receptor Agonist Omidenepag Does Not Affect Eyelash Growth in Mice
Esaki, Yoshihiko, Katsuta, Osamu, Kamio, Hitomi, Noto, Takahisa, Mano, Hidetoshi, Iwamura, Ryo, Yoneda, Kenji, Odani-Kawabata, Noriko, Morishima, Kenji, Shams, Naveed K
Published in Journal of ocular pharmacology and therapeutics (01.09.2020)
Published in Journal of ocular pharmacology and therapeutics (01.09.2020)
Get more information
Journal Article
Antiplatelet action of R‐99224, an active metabolite of a novel thienopyridine‐type G i ‐linked P2T antagonist, CS‐747
Sugidachi, Atsuhiro, Asai, Fumitoshi, Yoneda, Kenji, Iwamura, Ryo, Ogawa, Taketoshi, Otsuguro, Ken‐ichi, Koike, Hiroyuki
Published in British journal of pharmacology (29.01.2009)
Published in British journal of pharmacology (29.01.2009)
Get full text
Journal Article
Bicyclic nitrogenated heterocyclic compound
Hayashi, Norimitsu, Tsuzaki, Yasunori, Ishizawa, Kouhei, Nakajima, Tatsuo, Iwamura, Ryo, Tsuboike, Kazunari
Year of Publication 10.09.2020
Get full text
Year of Publication 10.09.2020
Patent
BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND
TSUZAKI, Yasunori, NAKAJIMA, Tatsuo, ISHIZAWA, Kouhei, HAYASHI, Norimitsu, TSUBOIKE, Kazunari, IWAMURA, Ryo
Year of Publication 26.08.2020
Get full text
Year of Publication 26.08.2020
Patent
PYRIDYLAMINOACETIC ACID COMPOUND
OKANARI, EIJI, TANAKA, MASAYUKI, FUJIWARA, HIROSHI, KATSUBE, TETSUSHI, SHIGETOMI, MANABU, IWAMURA, RYO, TOKUNAGA, YASUNORI
Year of Publication 31.07.2019
Get full text
Year of Publication 31.07.2019
Patent
PYRIDYLAMINOACETIC ACID COMPOUND
SHIGETOMI, Manabu, KATSUBE, Tetsushi, TOKUNAGA, Yasunori, FUJIWARA, Hiroshi, IWAMURA, Ryo, TANAKA, Masayuki, OKANARI, Eiji
Year of Publication 29.07.2019
Get full text
Year of Publication 29.07.2019
Patent
NOVEL 3-AZABICYCLO[3.1.0]HEXANE DERIVATIVE AND USE THEREOF AS U-OPIOID RECEPTOR ANTAGONIST
SHIMIZU, MOTOHISA, SETOGUCHI, HIROYUKI, TSUZAKI, YASUNORI, TANIKO KAORI, KURUMAZUKA DAISUKE, IWAMURA, RYO, KIMURA, TOMIO, AKAZA, HIROTO, HARADA SATOKO, OKABE MORIO, IZUCHI TORU, MIYAZAWA TOSHIYUKI, KANEKO TATSUROH, IMURA, YUUKI
Year of Publication 01.06.2021
Get full text
Year of Publication 01.06.2021
Patent
Compuesto de ácido piridilaminoacético
SHIGETOMI, Manabu, KATSUBE, Tetsushi, TOKUNAGA, Yasunori, FUJIWARA, Hiroshi, IWAMURA, Ryo, TANAKA, Masayuki, OKANARI, Eiji
Year of Publication 04.07.2019
Get full text
Year of Publication 04.07.2019
Patent
BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND
TSUZAKI, Yasunori, NAKAJIMA, Tatsuo, ISHIZAWA, Kouhei, HAYASHI, Norimitsu, TSUBOIKE, Kazunari, IWAMURA, Ryo
Year of Publication 03.07.2019
Get full text
Year of Publication 03.07.2019
Patent