Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis
Wollin, Lutz, Maillet, Isabelle, Quesniaux, Valérie, Holweg, Alexander, Ryffel, Bernhard
Published in The Journal of pharmacology and experimental therapeutics (01.05.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2014)
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The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin
Di Domizio, Jeremy, Belkhodja, Cyrine, Chenuet, Pauline, Fries, Anissa, Murray, Timothy, Mondéjar, Paula Marcos, Demaria, Olivier, Conrad, Curdin, Homey, Bernhard, Werner, Sabine, Speiser, Daniel E., Ryffel, Bernhard, Gilliet, Michel
Published in Nature immunology (01.09.2020)
Published in Nature immunology (01.09.2020)
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Journal Article
STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)
Messaoud-Nacer, Yasmine, Culerier, Elodie, Rose, Stéphanie, Maillet, Isabelle, Rouxel, Nathalie, Briault, Sylvain, Ryffel, Bernhard, Quesniaux, Valerie F. J., Togbe, Dieudonnée
Published in Cell death & disease (25.03.2022)
Published in Cell death & disease (25.03.2022)
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Journal Article
AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging
Cordero, Mario D., Williams, Matthew R., Ryffel, Bernhard
Published in Trends in endocrinology and metabolism (01.01.2018)
Published in Trends in endocrinology and metabolism (01.01.2018)
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Journal Article
IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation
Tan, Zhongming, Qian, Xiaofeng, Jiang, Runqiu, Liu, Qianghui, Wang, Youjing, Chen, Chen, Wang, Xuehao, Ryffel, Bernhard, Sun, Beicheng
Published in The Journal of immunology (1950) (15.08.2013)
Published in The Journal of immunology (1950) (15.08.2013)
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Journal Article
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway
Holze, Cathleen, Michaudel, Chloé, Mackowiak, Claire, Haas, Darya A., Benda, Christian, Hubel, Philipp, Pennemann, Friederike L., Schnepf, Daniel, Wettmarshausen, Jennifer, Braun, Marianne, Leung, Daisy W., Amarasinghe, Gaya K., Perocchi, Fabiana, Staeheli, Peter, Ryffel, Bernhard, Pichlmair, Andreas
Published in Nature immunology (01.02.2018)
Published in Nature immunology (01.02.2018)
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Journal Article
A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy
Douguet, Laetitia, Janho dit Hreich, Serena, Benzaquen, Jonathan, Seguin, Laetitia, Juhel, Thierry, Dezitter, Xavier, Duranton, Christophe, Ryffel, Bernhard, Kanellopoulos, Jean, Delarasse, Cecile, Renault, Nicolas, Furman, Christophe, Homerin, Germain, Féral, Chloé, Cherfils-Vicini, Julien, Millet, Régis, Adriouch, Sahil, Ghinet, Alina, Hofman, Paul, Vouret-Craviari, Valérie
Published in Nature communications (28.01.2021)
Published in Nature communications (28.01.2021)
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Journal Article
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses
Hrdý, Jiří, Alard, Jeanne, Couturier-Maillard, Aurelie, Boulard, Olivier, Boutillier, Denise, Delacre, Myriam, Lapadatescu, Carmen, Cesaro, Annabelle, Blanc, Philippe, Pot, Bruno, Ryffel, Bernhard, Chamaillard, Mathias, Grangette, Corinne
Published in Scientific reports (24.03.2020)
Published in Scientific reports (24.03.2020)
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Journal Article
STING-dependent sensing of self-DNA drives silica-induced lung inflammation
Benmerzoug, Sulayman, Rose, Stéphanie, Bounab, Badreddine, Gosset, David, Duneau, Laure, Chenuet, Pauline, Mollet, Lucile, Le Bert, Marc, Lambers, Christopher, Geleff, Silvana, Roth, Michael, Fauconnier, Louis, Sedda, Delphine, Carvalho, Clarisse, Perche, Olivier, Laurenceau, David, Ryffel, Bernhard, Apetoh, Lionel, Kiziltunc, Ahmet, Uslu, Hakan, Albez, Fadime Sultan, Akgun, Metin, Togbe, Dieudonnée, Quesniaux, Valerie F. J.
Published in Nature communications (06.12.2018)
Published in Nature communications (06.12.2018)
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Journal Article
The receptor NLRP3 is a transcriptional regulator of TH2 differentiation
Bruchard, Mélanie, Rebé, Cédric, Derangère, Valentin, Togbé, Dieudonnée, Ryffel, Bernhard, Boidot, Romain, Humblin, Etienne, Hamman, Arlette, Chalmin, Fanny, Berger, Hélène, Chevriaux, Angélique, Limagne, Emeric, Apetoh, Lionel, Végran, Frédérique, Ghiringhelli, François
Published in Nature immunology (01.08.2015)
Published in Nature immunology (01.08.2015)
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Journal Article
Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses
Bruchard, Mélanie, Geindreau, Mannon, Perrichet, Anaïs, Truntzer, Caroline, Ballot, Elise, Boidot, Romain, Racoeur, Cindy, Barsac, Emilie, Chalmin, Fanny, Hibos, Christophe, Baranek, Thomas, Paget, Christophe, Ryffel, Bernhard, Rébé, Cédric, Paul, Catherine, Végran, Frédérique, Ghiringhelli, François
Published in Nature immunology (01.02.2022)
Published in Nature immunology (01.02.2022)
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Journal Article
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
Bruchard, Mélanie, Mignot, Grégoire, Derangère, Valentin, Chalmin, Fanny, Chevriaux, Angélique, Végran, Frédérique, Boireau, Wilfrid, Simon, Benoit, Ryffel, Bernhard, Connat, Jean Louis, Kanellopoulos, Jean, Martin, François, Rébé, Cédric, Apetoh, Lionel, Ghiringhelli, François
Published in Nature Medicine (01.01.2013)
Published in Nature Medicine (01.01.2013)
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Magazine Article
Editorial: Ozone as a Driver of Lung Inflammation and Innate Immunity and as a Model for Lung Disease
Chung, Kian Fan, Togbe, Dieudonnée, Ryffel, Bernhard
Published in Frontiers in immunology (30.06.2021)
Published in Frontiers in immunology (30.06.2021)
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Journal Article
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
Marín‐Aguilar, Fabiola, Lechuga‐Vieco, Ana V., Alcocer‐Gómez, Elísabet, Castejón‐Vega, Beatriz, Lucas, Javier, Garrido, Carlos, Peralta‐Garcia, Alejandro, Pérez‐Pulido, Antonio J., Varela‐López, Alfonso, Quiles, José L., Ryffel, Bernhard, Flores, Ignacio, Bullón, Pedro, Ruiz‐Cabello, Jesús, Cordero, Mario D.
Published in Aging cell (01.01.2020)
Published in Aging cell (01.01.2020)
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Journal Article
Extracellular ATP Is a Danger Signal Activating P2X7 Receptor in Lung Inflammation and Fibrosis
RITEAU, Nicolas, GASSE, Pamela, RYFFEL, Bernhard, COUILLIN, Isabelle, FAUCONNIER, Louis, GOMBAULT, Aurélie, COUEGNAT, Marion, FICK, Lizette, KANELLOPOULOS, Jean, QUESNIAUX, Valérie F. J, MARCHAND-ADAM, Sylvain, CRESTANI, Bruno
Published in American journal of respiratory and critical care medicine (15.09.2010)
Published in American journal of respiratory and critical care medicine (15.09.2010)
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Journal Article
Gain of function mutation and inflammasome driven diseases in human and mouse models
Cordero, Mario D., Alcocer-Gómez, Elísabet, Ryffel, Bernhard
Published in Journal of autoimmunity (01.07.2018)
Published in Journal of autoimmunity (01.07.2018)
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Journal Article
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions
Lu, Ling, Lan, Qin, Li, Zhiyuan, Zhou, Xiaohui, Gu, Jian, Li, Qiang, Wang, Julie, Chen, Maogen, Liu, Ya, Shen, Yi, Brand, David D, Ryffel, Bernhard, Horwitz, David A, Quismorio, Francisco P, Liu, Zhongmin, Li, Bin, Olsen, Nancy J, Zheng, Song Guo
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2014)
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