Rhodium(III)-Catalyzed C–H Activation: Ligand-Controlled Regioselective Synthesis of 4‑Methyl-Substituted Dihydroisoquinolones
Barber, Joyann S, Scales, Stephanie, Tran-Dubé, Michelle, Wang, Fen, Sach, Neal W, Bernier, Louise, Collins, Michael R, Zhu, JinJiang, McAlpine, Indrawan J, Patman, Ryan L
Published in Organic letters (19.07.2019)
Published in Organic letters (19.07.2019)
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SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance
Jensen-Pergakes, Kristen, Tatlock, John, Maegley, Karen A, McAlpine, Indrawan J, McTigue, Michele, Xie, Tao, Dillon, Christopher P, Wang, Yuli, Yamazaki, Shinji, Spiegel, Noah, Shi, Manli, Nemeth, Amy, Miller, Natalie, Hendrickson, Eleanore, Lam, Hieu, Sherrill, John, Chung, Chi-Yeh, McMillan, Elizabeth A, Bryant, Shannon Karlicek, Palde, Prakash, Braganza, John, Brooun, Alexei, Deng, Ya-Li, Goshtasbi, Vesta, Kephart, Susan E, Kumpf, Robert A, Liu, Wei, Patman, Ryan L, Rui, Eugene, Scales, Stephanie, Tran-Dube, Michelle, Wang, Fen, Wythes, Martin, Paul, Thomas A
Published in Molecular cancer therapeutics (01.01.2022)
Published in Molecular cancer therapeutics (01.01.2022)
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Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles
Derosa, Joseph, O’Duill, Miriam L, Holcomb, Matthew, Boulous, Mark N, Patman, Ryan L, Wang, Fen, Tran-Dubé, Michelle, McAlpine, Indrawan, Engle, Keary M
Published in Journal of organic chemistry (06.04.2018)
Published in Journal of organic chemistry (06.04.2018)
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Construction of Isoquinolone Scaffolds on DNA via Rhodium(III)-Catalyzed C–H Activation
Ye, Yusong, Berry, Madeline, Bock, William J., Cheng, Kunpeng, Nair, Sajiv K., Park, Christiana S., Patman, Ryan L., Sakata, Sylvie, Tran-Dubé, Michelle, Donaldson, Joyann S., Yang, Guanyu, Liu, Guansai
Published in Organic letters (26.04.2024)
Published in Organic letters (26.04.2024)
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Catalytic C−C Coupling via Transfer Hydrogenation: Reverse Prenylation, Crotylation, and Allylation from the Alcohol or Aldehyde Oxidation Level
Bower, John F, Skucas, Eduardas, Patman, Ryan L, Krische, Michael J
Published in Journal of the American Chemical Society (12.12.2007)
Published in Journal of the American Chemical Society (12.12.2007)
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Direct Vinylation of Alcohols or Aldehydes Employing Alkynes as Vinyl Donors: A Ruthenium Catalyzed C−C Bond-Forming Transfer Hydrogenation
Patman, Ryan L, Chaulagain, Mani Raj, Williams, Vanessa M, Krische, Michael J
Published in Journal of the American Chemical Society (18.02.2009)
Published in Journal of the American Chemical Society (18.02.2009)
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Multifaceted Substrate–Ligand Interactions Promote the Copper-Catalyzed Hydroboration of Benzylidenecyclobutanes and Related Compounds
Kang, Taeho, Erbay, Tuğçe G, Xu, Kane L, Gallego, Gary M, Burtea, Alexander, Nair, Sajiv K, Patman, Ryan L, Zhou, Ru, Sutton, Scott C, McAlpine, Indrawan J, Liu, Peng, Engle, Keary M
Published in ACS catalysis (06.11.2020)
Published in ACS catalysis (06.11.2020)
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Carbonyl Propargylation from the Alcohol or Aldehyde Oxidation Level Employing 1,3-Enynes as Surrogates to Preformed Allenylmetal Reagents: A Ruthenium-Catalyzed CC Bond-Forming Transfer Hydrogenation
Patman, Ryan L., Williams, Vanessa M., Bower, John F., Krische, Michael J.
Published in Angewandte Chemie (International ed.) (27.06.2008)
Published in Angewandte Chemie (International ed.) (27.06.2008)
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Journal Article
Divergent Regioselectivity in the Synthesis of Trisubstituted Allylic Alcohols by Nickel- and Ruthenium-Catalyzed Alkyne Hydrohydroxymethylation with Formaldehyde
Bausch, Cory C., Patman, Ryan L., Breit, Bernhard, Krische, Michael J.
Published in Angewandte Chemie (International ed.) (14.06.2011)
Published in Angewandte Chemie (International ed.) (14.06.2011)
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Journal Article
Development of a Late-Stage Diversification Strategy for the 4- and 5‑Positions of 4,5,6-Trisubstituted Indazoles
Barber, Joyann S, Burtea, Alexander, Collins, Michael R, Tran-Dubé, Michelle, Patman, Ryan L, Scales, Stephanie, Smith, Graham, Spangler, Jillian E, Wang, Fen, Wang, Wei, Yang, Shouliang, Zhu, JinJiang, Montgomery, T. Patrick
Published in Organic letters (20.11.2020)
Published in Organic letters (20.11.2020)
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Hydroacylation of 2-butyne from the alcohol or aldehyde oxidation level via ruthenium catalyzed C–C bond forming transfer hydrogenation
Williams, Vanessa M., Leung, Joyce C., Patman, Ryan L., Krische, Michael J.
Published in Tetrahedron (27.06.2009)
Published in Tetrahedron (27.06.2009)
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Conference Proceeding
Cu-Catalyzed Hydroboration of Benzylidenecyclopropanes: Reaction Optimization, (Hetero)Aryl Scope, and Origins of Pathway Selectivity
Medina, Jose M, Kang, Taeho, Erbay, Tuğçe G, Shao, Huiling, Gallego, Gary M, Yang, Shouliang, Tran-Dubé, Michelle, Richardson, Paul F, Derosa, Joseph, Helsel, Ryan T, Patman, Ryan L, Wang, Fen, Ashcroft, Christopher P, Braganza, John F, McAlpine, Indrawan, Liu, Peng, Engle, Keary M
Published in ACS catalysis (06.12.2019)
Published in ACS catalysis (06.12.2019)
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Alkyne-Aldehyde Reductive CC Coupling through Ruthenium-Catalyzed Transfer Hydrogenation: Direct Regio- and Stereoselective Carbonyl Vinylation to Form Trisubstituted Allylic Alcohols in the Absence of Premetallated Reagents
Leung, Joyce C., Patman, Ryan L., Sam, Brannon, Krische, Michael J.
Published in Chemistry : a European journal (24.10.2011)
Published in Chemistry : a European journal (24.10.2011)
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Journal Article
Enantioselective Carbonyl Allylation, Crotylation, and tert-Prenylation of Furan Methanols and Furfurals via Iridium-Catalyzed Transfer Hydrogenation
Bechem, Benjamin, Patman, Ryan L, Hashmi, A. Stephen K, Krische, Michael J
Published in Journal of organic chemistry (05.03.2010)
Published in Journal of organic chemistry (05.03.2010)
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Journal Article
Divergent Regioselectivity in the Synthesis of Trisubstituted Allylic Alcohols by Nickel- and Ruthenium-Catalyzed Alkyne Hydrohydroxymethylation with Formaldehyde
Bausch, Cory C., Patman, Ryan L., Breit, Bernhard, Krische, Michael J.
Published in Angewandte Chemie (14.06.2011)
Published in Angewandte Chemie (14.06.2011)
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Journal Article
Rhodium(III)-Catalyzed C-H Activation: Annulation of Petrochemical Feedstocks for the Construction of Isoquinolone Scaffolds
Barber, Joyann S., Kong, Dehuan, Li, Wei, McAlpine, Indrawan J., Nair, Sajiv K., Sakata, Sylvie K., Sun, Nicole, Patman, Ryan L.
Published in Synlett (22.01.2021)
Published in Synlett (22.01.2021)
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Abstract 1160: SAM competitive PRMT5 inhibitor PF06939999 demonstrates antitumor activity in splicing dysregulated NSCLC with decreased liability of drug resistance
Jensen-Pergakes, Kristen, Tatlock, John, Maegley, Karen, McAlpine, Indrawan, McTigue, Michele, Xie, Tao, Dillon, Christopher, Wang, Yuli, Yamazaki, Shinji, Spiegel, Noah, Shi, Manli, Nemeth, Amy, Miller, Natalie, Hendrickson, Eleanore, Lam, Hieu, Sherrill, John, Liu, Wei, Deng, Ya-Li, Chung, Chi-Yeh, McMillan, Elizabeth A., Palde, Prakash, Brooun, Alexei, Braganza, John, Kephart, Susan E., Kumpf, Robert, Patman, Ryan, Rui, Eugene, Scales, Stephanie, Tran-Dube, Michelle, Wang, Fen, Wythes, Martin, Paul, Thomas
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 4857: Discovery of PF-06855800, a SAM competitive PRMT5 inhibitor with potent antitumor activity
Mcalpine, Indrawan J., Tatlock, John, Billitti, Joseph, Braganza, John, Brooun, Alexei, Ya-Li, Deng, Hirakawa, Brad, Jensen-Pergakes, Kristen, Kumpf, Robert, Liu, Wei, Maegley, Karen, McTigue, Michele, Patman, Ryan, Rui, Eugene, Scales, Stephanie, Spiegel, Noah, Tran-Dubé, Michelle, Wang, Fen, Wang, Zhenxiong, Yamazaki, Shinji, Zhang, Tao, Wythes, Martin
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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