A beneficial adaptive role for CHOP in driving cell fate selection during ER stress
Liu, Kaihua, Zhao, Chaoxian, Adajar, Reed C, DeZwaan-McCabe, Diane, Rutkowski, D Thomas
Published in EMBO reports (12.01.2024)
Published in EMBO reports (12.01.2024)
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Journal Article
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
Rutkowski, D Thomas, Arnold, Stacey M, Miller, Corey N, Wu, Jun, Li, Jack, Gunnison, Kathryn M, Mori, Kazutoshi, Sadighi Akha, Amir A, Raden, David, Kaufman, Randal J
Published in PLoS biology (01.11.2006)
Published in PLoS biology (01.11.2006)
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Journal Article
C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver
Chikka, Madhusudana R., McCabe, Diane DeZwaan, Tyra, Heather M., Rutkowski, D. Thomas
Published in The Journal of biological chemistry (08.02.2013)
Published in The Journal of biological chemistry (08.02.2013)
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Journal Article
Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway
Hassan, Ihab H., Zhang, Michael S., Powers, Linda S., Shao, Jian Q., Baltrusaitis, Jonas, Rutkowski, D. Thomas, Legge, Kevin, Monick, Martha M.
Published in The Journal of biological chemistry (10.02.2012)
Published in The Journal of biological chemistry (10.02.2012)
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Journal Article
Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response
Zhang, Kezhong, Shen, Xiaohua, Wu, Jun, Sakaki, Kenjiro, Saunders, Thomas, Rutkowski, D. Thomas, Back, Sung Hoon, Kaufman, Randal J.
Published in Cell (10.02.2006)
Published in Cell (10.02.2006)
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Journal Article
UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators
Rutkowski, D. Thomas, Wu, Jun, Back, Sung-Hoon, Callaghan, Michael U., Ferris, Sean P., Iqbal, Jahangir, Clark, Robert, Miao, Hongzhi, Hassler, Justin R., Fornek, Jamie, Katze, Michael G., Hussain, M. Mahmood, Song, Benbo, Swathirajan, Jayanth, Wang, Junying, Yau, Grace D.-Y., Kaufman, Randal J.
Published in Developmental cell (01.12.2008)
Published in Developmental cell (01.12.2008)
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Journal Article
The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis
DeZwaan-McCabe, Diane, Riordan, Jesse D, Arensdorf, Angela M, Icardi, Michael S, Dupuy, Adam J, Rutkowski, D Thomas
Published in PLoS genetics (01.12.2013)
Published in PLoS genetics (01.12.2013)
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Journal Article
ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis
DeZwaan-McCabe, Diane, Sheldon, Ryan D., Gorecki, Michelle C., Guo, Deng-Fu, Gansemer, Erica R., Kaufman, Randal J., Rahmouni, Kamal, Gillum, Matthew P., Taylor, Eric B., Teesch, Lynn M., Rutkowski, D. Thomas
Published in Cell reports (Cambridge) (30.05.2017)
Published in Cell reports (Cambridge) (30.05.2017)
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Journal Article
NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis
Gansemer, Erica R., McCommis, Kyle S., Martino, Michael, King-McAlpin, Abdul Qaadir, Potthoff, Matthew J., Finck, Brian N., Taylor, Eric B., Rutkowski, D. Thomas
Published in iScience (22.05.2020)
Published in iScience (22.05.2020)
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Journal Article
Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences
Arensdorf, Angela M, Diedrichs, Danilo, Rutkowski, D Thomas
Published in Frontiers in genetics (02.12.2013)
Published in Frontiers in genetics (02.12.2013)
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Journal Article
Interference with the HNF4-dependent gene regulatory network diminishes endoplasmic reticulum stress in hepatocytes
Shah, Anit, Huck, Ian, Duncan, Kaylia, Gansemer, Erica R, Liu, Kaihua, Adajar, Reed C, Apte, Udayan, Stamnes, Mark A, Rutkowski, D Thomas
Published in Hepatology communications (01.11.2023)
Published in Hepatology communications (01.11.2023)
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Journal Article
Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS
Wang, Jiou, Farr, George W, Zeiss, Caroline J, Rodriguez-Gil, Diego J, Wilson, Jean H, Furtak, Krystyna, Rutkowski, D. Thomas, Kaufman, Randal J, Ruse, Cristian I, Yates, John R. III, Perrin, Steve, Feany, Mel B, Horwich, Arthur L
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.2009)
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Journal Article
Heightened Induction of Proapoptotic Signals in Response to Endoplasmic Reticulum Stress in Primary Fibroblasts from a Mouse Model of Longevity
Sadighi Akha, Amir A., Harper, James M., Salmon, Adam B., Schroeder, Bethany A., Tyra, Heather M., Rutkowski, D. Thomas, Miller, Richard A.
Published in The Journal of biological chemistry (02.09.2011)
Published in The Journal of biological chemistry (02.09.2011)
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