AI-based antibody discovery platform identifies novel, diverse, and pharmacologically active therapeutic antibodies against multiple SARS-CoV-2 strains
Loomis, Cristina Moldovan, Lahlali, Thomas, Van Citters, Danielle, Sprague, Megan, Neveu, Gregory, Somody, Laurence, Siska, Christine C, Deming, Derrick, Asakawa, Andrew J, Amimeur, Tileli, Shaver, Jeremy M, Carbonelle, Caroline, Ketchem, Randal R, Alam, Antoine, Clark, Rutilio H
Published in Antibody therapeutics (01.10.2024)
Published in Antibody therapeutics (01.10.2024)
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Journal Article
CHO cell production and sequence improvement in the 13C6FR1 anti-Ebola antibody
Pettit, Dean K, Rogers, Richard S, Arthur, Kelly, Brodsky, Yan, Clark, Rutilio H, Crowell, Chris, Ennis, Jane, Gillespie, Alison, Gillespie, Ron, Livingston, Brittney, Nalbandian, Edith, Pace, Danielle, Smidt, Pauline, Pauly, Michael, Timmons, Ken, Trentalange, Michael, Whaley, Kevin J, Zeitlin, Larry, Thomas, James N
Published in mAbs (01.01.2016)
Published in mAbs (01.01.2016)
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Journal Article
A Peptide that Inhibits Hydroxyapatite Growth is in an Extended Conformation on the Crystal Surface
Long, Joanna R., Dindot, John L., Zebroski, Henry, Kiihne, Suzanne, Clark, Rutilio H., Campbell, Allison A., Stayton, Patrick S., Drobny, Gary P.
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.1998)
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Journal Article
A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism
Liu, Zhi, Leng, Esther C., Gunasekaran, Kannan, Pentony, Martin, Shen, Min, Howard, Monique, Stoops, Janelle, Manchulenko, Kathy, Razinkov, Vladimir, Liu, Hua, Fanslow, William, Hu, Zhonghua, Sun, Nancy, Hasegawa, Haruki, Clark, Rutilio, Foltz, Ian N., Yan, Wei
Published in The Journal of biological chemistry (20.03.2015)
Published in The Journal of biological chemistry (20.03.2015)
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Journal Article
Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity
Kerwin, Bruce A., Bennett, Chelsey, Brodsky, Yan, Clark, Rutilio, Floyd, J. Alaina, Gillespie, Alison, Mayer, Bryan T., McClure, Megan, Siska, Christine, Seaman, Michael S., Seaton, Kelly E., Shaver, Jeremy, Tomaras, Georgia D., Yates, Nicole L., Ketchem, Randal R.
Published in Journal of pharmaceutical sciences (01.01.2020)
Published in Journal of pharmaceutical sciences (01.01.2020)
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Journal Article
Designing Feature-Controlled Humanoid Antibody Discovery Libraries Using Generative Adversarial Networks
Amimeur, Tileli, Shaver, Jeremy M, Ketchem, Randal R, Taylor, J Alex, Clark, Rutilio H, Smith, Josh, Danielle Van Citters, Siska, Christine C, Smidt, Pauline, Sprague, Megan, Kerwin, Bruce A, Pettit, Dean
Published in bioRxiv (13.04.2020)
Published in bioRxiv (13.04.2020)
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Paper
ST2 ANTIGEN BINDING PROTEINS
DIRK E SMITH, CHADWICK T KING, MIN XIAOSHAN, RUTILIO CLARK, MICHAEL R COMEAU, LIM AI CHING, RANDAL R KET, FOLTZ IAN, WANG ZHULUN, SHI DONGHUI
Year of Publication 22.10.2020
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Year of Publication 22.10.2020
Patent
ST2 ANTIGEN BINDING PROTEINS
DIRK E SMITH, CHADWICK T KING, MIN XIAOSHAN, RUTILIO CLARK, MICHAEL R COMEAU, LIM AI CHING, RANDAL R KET, FOLTZ IAN, WANG ZHULUN, SHI DONGHUI
Year of Publication 17.01.2019
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Year of Publication 17.01.2019
Patent
ST2 ANTIGEN BINDING PROTEINS
DIRK E SMITH, CHADWICK T KING, MIN XIAOSHAN, RUTILIO CLARK, MICHAEL R COMEAU, LIM AI CHING, RANDAL R KET, FOLTZ IAN, WANG ZHULUN, SHI DONGHUI
Year of Publication 13.10.2016
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Year of Publication 13.10.2016
Patent
HUMAN CD30 LIGAND ANTIGEN BINDING PROTEINS
CLARK, Rutilio, ANDERSEN, Mette Dahl, ARMITAGE, Richard J, DANTZLER, Jeff
Year of Publication 04.10.2023
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Year of Publication 04.10.2023
Patent
HUMAN CD30 LIGAND ANTIGEN BINDING PROTEINS
CLARK, Rutilio, ANDERSEN, Mette Dahl, ARMITAGE, Richard J, DANTZLER, Jeff
Year of Publication 23.08.2023
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Year of Publication 23.08.2023
Patent
Human CD30 ligand antigen binding proteins
CLARK, Rutilio, ANDERSEN, Mette Dahl, ARMITAGE, Richard J, DANTZLER, Jeff
Year of Publication 20.10.2022
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Year of Publication 20.10.2022
Patent
Generation of protein sequences using machine learning techniques
CLARK, Rutilio H, TAYLOR, John Alex, AMIMEUR, Tileli, SHAVER, Jeremy Martin, KET, Randal Robert
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
Patent
GENERATION OF PROTEIN SEQUENCES USING MACHINE LEARNING TECHNIQUES
CLARK, Rutilio H, TAYLOR, John Alex, AMIMEUR, Tileli, SHAVER, Jeremy Martin, KET, Randal Robert
Year of Publication 01.05.2024
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Year of Publication 01.05.2024
Patent
MACHINE LEARNING ARCHITECTURE TO GENERATE PROTEIN SEQUENCES
CLARK, Rutilio H, TAYLOR, Alex, AMIMEUR, Tileli, SHAVER, Jeremy Martin, KET, Randal Robert
Year of Publication 11.04.2024
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Year of Publication 11.04.2024
Patent
HUMAN CD30 LIGAND ANTIGEN BINDING PROTEINS
CLARK, RUTILIO, ARMITAGE RICHARD J, ANDERSEN, METTE DAHL, DANTZLER, JEFF
Year of Publication 25.05.2022
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Year of Publication 25.05.2022
Patent
Human CD30 ligand antigen binding proteins
Andersen, Mette Dahl, Clark, Rutilio, Dantzler, Jeff, Armitage, Richard J
Year of Publication 19.05.2022
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Year of Publication 19.05.2022
Patent