Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders
Kang, Soojeong, Dahl, Russell, Hsieh, Wilson, Shin, Andrew, Zsebo, Krisztina M., Buettner, Christoph, Hajjar, Roger J., Lebeche, Djamel
Published in The Journal of biological chemistry (04.03.2016)
Published in The Journal of biological chemistry (04.03.2016)
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Journal Article
Positive Allosteric Modulators of SERCA Pump Restore Dendritic Spines and Rescue Long-Term Potentiation Defects in Alzheimer's Disease Mouse Model
Rakovskaya, Anastasiya, Erofeev, Alexander, Vinokurov, Egor, Pchitskaya, Ekaterina, Dahl, Russell, Bezprozvanny, Ilya
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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Journal Article
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
Kho, Changwon, Lee, Ahyoung, Jeong, Dongtak, Oh, Jae Gyun, Gorski, Przemek A., Fish, Kenneth, Sanchez, Roberto, DeVita, Robert J., Christensen, Geir, Dahl, Russell, Hajjar, Roger J.
Published in Nature communications (12.06.2015)
Published in Nature communications (12.06.2015)
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Journal Article
Positive Allosteric Modulator of SERCA Pump NDC-1173 Exerts Beneficial Effects in Mouse Model of Alzheimer's Disease
Dahl, Russell, Moore, Amanda C, Knight, Caitlynn, Mauger, Colleen, Zhang, Hua, Schiltz, Gary E, Koss, Wendy A, Bezprozvanny, Ilya
Published in International journal of molecular sciences (01.07.2023)
Published in International journal of molecular sciences (01.07.2023)
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Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor
Pinkerton, Anthony B., Sergienko, Eduard, Bravo, Yalda, Dahl, Russell, Ma, Chen-Ting, Sun, Qing, Jackson, Michael R., Cosford, Nicholas D.P., Millán, José Luis
Published in Bioorganic & medicinal chemistry letters (01.01.2018)
Published in Bioorganic & medicinal chemistry letters (01.01.2018)
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Journal Article
A Gatekeeper Residue for NEDD8-Activating Enzyme Inhibition by MLN4924
Toth, Julia I., Yang, Li, Dahl, Russell, Petroski, Matthew D.
Published in Cell reports (Cambridge) (19.04.2012)
Published in Cell reports (Cambridge) (19.04.2012)
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Journal Article
Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors
Noberini, Roberta, Koolpe, Mitchell, Peddibhotla, Satyamaheshwar, Dahl, Russell, Su, Ying, Cosford, Nicholas D.P., Roth, Gregory P., Pasquale, Elena B.
Published in The Journal of biological chemistry (24.10.2008)
Published in The Journal of biological chemistry (24.10.2008)
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Journal Article
Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells
Gruber, Simon J, Cornea, Razvan L, Li, Ji, Peterson, Kurt C, Schaaf, Tory M, Gillispie, Gregory D, Dahl, Russell, Zsebo, Krisztina M, Robia, Seth L, Thomas, David D
Published in Journal of biomolecular screening (01.02.2014)
Published in Journal of biomolecular screening (01.02.2014)
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Journal Article
Rapid Multistep Synthesis of 1,2,4-Oxadiazoles in a Single Continuous Microreactor Sequence
Grant, Daniel, Dahl, Russell, Cosford, Nicholas D. P
Published in Journal of organic chemistry (19.09.2008)
Published in Journal of organic chemistry (19.09.2008)
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Journal Article
Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy
Sano, Renata, Hou, Ying-Chen Claire, Hedvat, Michael, Correa, Ricardo G, Shu, Chih-Wen, Krajewska, Maryla, Diaz, Paul W, Tamble, Craig M, Quarato, Giovanni, Gottlieb, Roberta A, Yamaguchi, Masaya, Nizet, Victor, Dahl, Russell, Thomas, David D, Tait, Stephen W, Green, Douglas R, Fisher, Paul B, Matsuzawa, Shu-Ichi, Reed, John C
Published in Genes & development (15.05.2012)
Published in Genes & development (15.05.2012)
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Journal Article
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
Lu, Jie, Chan, Lai, Fiji, Hannah D G, Dahl, Russell, Kwon, Ohyun, Tamanoi, Fuyuhiko
Published in Molecular cancer therapeutics (01.05.2009)
Published in Molecular cancer therapeutics (01.05.2009)
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Journal Article
Design and Synthesis of Systemically Active Metabotropic Glutamate Subtype‑2 and -3 (mGlu2/3) Receptor Positive Allosteric Modulators (PAMs): Pharmacological Characterization and Assessment in a Rat Model of Cocaine Dependence
Dhanya, Raveendra-Panickar, Sheffler, Douglas J, Dahl, Russell, Davis, Melinda, Lee, Pooi San, Yang, Li, Nickols, Hilary Highfield, Cho, Hyekyung P, Smith, Layton H, D’Souza, Manoranjan S, Conn, P. Jeffrey, Der-Avakian, Andre, Markou, Athina, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (22.05.2014)
Published in Journal of medicinal chemistry (22.05.2014)
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Journal Article
Design, Synthesis, and Structure−Activity Relationship of Substrate Competitive, Selective, and in Vivo Active Triazole and Thiadiazole Inhibitors of the c-Jun N-Terminal Kinase
De, Surya K, Stebbins, John L, Chen, Li-Hsing, Riel-Mehan, Megan, Machleidt, Thomas, Dahl, Russell, Yuan, Hongbin, Emdadi, Aras, Barile, Elisa, Chen, Vida, Murphy, Ria, Pellecchia, Maurizio
Published in Journal of medicinal chemistry (09.04.2009)
Published in Journal of medicinal chemistry (09.04.2009)
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Journal Article
High-throughput FRET assay yields allosteric SERCA activators
Cornea, Razvan L, Gruber, Simon J, Lockamy, Elizabeth L, Muretta, Joseph M, Jin, Dongzhu, Chen, Jiqiu, Dahl, Russell, Bartfai, Tamas, Zsebo, Krisztina M, Gillispie, Gregory D, Thomas, David D
Published in Journal of biomolecular screening (01.01.2013)
Published in Journal of biomolecular screening (01.01.2013)
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Journal Article
Preclinical Studies of Celastrol and Acetyl Isogambogic Acid in Melanoma
ABBAS, Sabiha, BHOUMIK, Anindita, DAHL, Russell, VASILE, Stefan, KRAJEWSKI, Stan, COSFORD, Nicholas D. P, RONAI, Zeev A
Published in Clinical cancer research (15.11.2007)
Published in Clinical cancer research (15.11.2007)
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Journal Article
Phosphomannose Isomerase Inhibitors Improve N-Glycosylation in Selected Phosphomannomutase-deficient Fibroblasts
Sharma, Vandana, Ichikawa, Mie, He, Ping, Bravo, Yalda, Dahl, Russell, Ng, Bobby G., Cosford, Nicholas D.P., Freeze, Hudson H.
Published in The Journal of biological chemistry (11.11.2011)
Published in The Journal of biological chemistry (11.11.2011)
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Journal Article
A Surprising Dipolar Cycloaddition Provides Ready Access to Aminoglycosides
Dahl, Russell S, Finney, Nathaniel S
Published in Journal of the American Chemical Society (14.07.2004)
Published in Journal of the American Chemical Society (14.07.2004)
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