Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis
Verscheijden, Laurens F M, Koenderink, Jan B, de Wildt, Saskia N, Russel, Frans G M
Published in PLoS computational biology (01.06.2019)
Published in PLoS computational biology (01.06.2019)
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Journal Article
Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations
Mutsaers, Henricus A M, van den Heuvel, Lambertus P, Ringens, Lauke H J, Dankers, Anita C A, Russel, Frans G M, Wetzels, Jack F M, Hoenderop, Joost G, Masereeuw, Rosalinde
Published in PloS one (04.04.2011)
Published in PloS one (04.04.2011)
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Journal Article
Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP
Lempers, Vincent J C, van den Heuvel, Jeroen J M W, Russel, Frans G M, Aarnoutse, Rob E, Burger, David M, Brüggemann, Roger J, Koenderink, Jan B
Published in Antimicrobial agents and chemotherapy (01.06.2016)
Published in Antimicrobial agents and chemotherapy (01.06.2016)
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Journal Article
Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells
van der Pol, Karel H, Koenderink, Jan, van den Heuvel, Jeroen J M W, van den Broek, Petra, Peters, Janny, van Bunningen, Imke D W, Pertijs, Jeanne, Russel, Frans G M, Koldenhof, Jim, Morshuis, Wim J, van Drongelen, Joris, Schirris, Tom J J, van der Meer, Andries, Rongen, Gerard A
Published in PloS one (21.06.2024)
Published in PloS one (21.06.2024)
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Journal Article
Mitochondrial complex III activity: from invasive muscle biopsies to patient-friendly buccal swab analysis
Somers, Tim, Allard, Neeltje A. E., Siddiqi, Sailay, Janssen, Margit C. M., Hopman, Maria T. E., Morshuis, Wim J., Russel, Frans G. M., Timmers, Silvie, Schirris, Tom J. J.
Published in Scientific reports (14.06.2023)
Published in Scientific reports (14.06.2023)
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Journal Article
Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children
Verscheijden, Laurens F M, Litjens, Carlijn H C, Koenderink, Jan B, Mathijssen, Ron H J, Verbeek, Marcel M, de Wildt, Saskia N, Russel, Frans G M
Published in PLoS computational biology (04.03.2021)
Published in PLoS computational biology (04.03.2021)
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Journal Article
Usage patterns of personal care products: Important factors for exposure assessment
Biesterbos, Jacqueline W.H., Dudzina, Tatsiana, Delmaar, Christiaan J.E., Bakker, Martine I., Russel, Frans G.M., von Goetz, Natalie, Scheepers, Paul T.J., Roeleveld, Nel
Published in Food and chemical toxicology (01.05.2013)
Published in Food and chemical toxicology (01.05.2013)
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Journal Article
Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates
Koenderink, Jan B., van den Heuvel, Jeroen J. M. W., Bilos, Ab, Vredenburg, Galvin, Vermeulen, Nico P. E., Russel, Frans G. M.
Published in Archives of toxicology (01.09.2020)
Published in Archives of toxicology (01.09.2020)
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Journal Article
Statin Lactonization by Uridine 5′-Diphospho-glucuronosyltransferases (UGTs)
Schirris, Tom J. J, Ritschel, Tina, Bilos, Albert, Smeitink, Jan A. M, Russel, Frans G. M
Published in Molecular pharmaceutics (02.11.2015)
Published in Molecular pharmaceutics (02.11.2015)
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Journal Article
Selective iNOS inhibition for the treatment of sepsis-induced acute kidney injury
Heemskerk, Suzanne, Masereeuw, Rosalinde, Russel, Frans G. M, Pickkers, Peter
Published in Nature reviews. Nephrology (01.11.2009)
Published in Nature reviews. Nephrology (01.11.2009)
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Journal Article
Uremic Solutes in Chronic Kidney Disease and Their Role in Progression
van den Brand, Jan A J G, Mutsaers, Henricus A M, van Zuilen, Arjan D, Blankestijn, Peter J, van den Broek, Petra H, Russel, Frans G M, Masereeuw, Rosalinde, Wetzels, Jack F M
Published in PloS one (29.12.2016)
Published in PloS one (29.12.2016)
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Journal Article
INTRAVENOUSLY ADMINISTERED SHORT INTERFERING RNA ACCUMULATES IN THE KIDNEY AND SELECTIVELY SUPPRESSES GENE FUNCTION IN RENAL PROXIMAL TUBULES
VAN DE WATER, Femke M, BOERMAN, Otto C, WOUTERSE, Alfons C, PETERS, Janny G. P, RUSSEL, Frans G. M, MASEREEUW, Rosalinde
Published in Drug metabolism and disposition (01.08.2006)
Published in Drug metabolism and disposition (01.08.2006)
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Journal Article
Statins and Cardiomyocyte Metabolism, Friend or Foe?
Somers, Tim, Siddiqi, Sailay, Morshuis, Wim J, Russel, Frans G. M, Schirris, Tom J. J
Published in Journal of cardiovascular development and disease (01.10.2023)
Published in Journal of cardiovascular development and disease (01.10.2023)
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Journal Article
Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones
Dankers, Anita C. A, Sweep, Fred C. G. J, Pertijs, Jeanne C. L. M, Verweij, Vivienne, van den Heuvel, Jeroen J. M. W, Koenderink, Jan B, Russel, Frans G. M, Masereeuw, Rosalinde
Published in Cell and tissue research (01.08.2012)
Published in Cell and tissue research (01.08.2012)
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Journal Article
Transporter-Mediated Cellular Distribution of Tyrosine Kinase Inhibitors as a Potential Resistance Mechanism in Chronic Myeloid Leukemia
Verhagen, Noor E, Koenderink, Jan B, Blijlevens, Nicole M. A, Janssen, Jeroen J. W. M, Russel, Frans G. M
Published in Pharmaceutics (01.10.2023)
Published in Pharmaceutics (01.10.2023)
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Journal Article
Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates
van der Velden, Maarten, Bilos, Albert, van den Heuvel, Jeroen J M W, Rijpma, Sanna R, Hurkmans, Evelien G E, Sauerwein, Robert W, Russel, Frans G M, Koenderink, Jan B
Published in Malaria journal (23.10.2017)
Published in Malaria journal (23.10.2017)
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Journal Article
Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment
Frambach, Sanne J C M, de Haas, Ria, Smeitink, Jan A M, Rongen, Gerard A, Russel, Frans G M, Schirris, Tom J J
Published in Pharmacological reviews (01.01.2020)
Published in Pharmacological reviews (01.01.2020)
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Journal Article
The ABCs of multidrug resistance in malaria
Koenderink, Jan B, Kavishe, Reginald A, Rijpma, Sanna R, Russel, Frans G.M
Published in Trends in parasitology (01.09.2010)
Published in Trends in parasitology (01.09.2010)
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Journal Article
Na+,K+‑ATPase Isoform Selectivity for Digitalis-Like Compounds Is Determined by Two Amino Acids in the First Extracellular Loop
Weigand, Karl M, Laursen, Mette, Swarts, Herman G. P, Engwerda, Anthonius H. J, Prüfert, Christian, Sandrock, Julia, Nissen, Poul, Fedosova, Natalya U, Russel, Frans G. M, Koenderink, Jan B
Published in Chemical research in toxicology (15.12.2014)
Published in Chemical research in toxicology (15.12.2014)
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Journal Article