PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure
Taylor, Roslyn A, Xiao, Sixia, Carias, Ann M, McRaven, Michael D, Thakkar, Divya N, Araínga, Mariluz, Allen, Edward J, Rogers, Kenneth A, Kumarapperuma, Sidath C, Gong, Siqi, Fought, Angela J, Anderson, Meegan R, Thomas, Yanique, Schneider, Jeffrey R, Goins, Beth, Fox, Peter, Villinger, Francois J, Ruprecht, Ruth M, Hope, Thomas J
Published in PLoS pathogens (01.06.2021)
Published in PLoS pathogens (01.06.2021)
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Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques
Virnik, Konstantin, Rosati, Margherita, Medvedev, Alexei, Scanlan, Aaron, Walsh, Gabrielle, Dayton, Frances, Broderick, Kate E, Lewis, Mark, Bryson, Yvonne, Lifson, Jeffrey D, Ruprecht, Ruth M, Felber, Barbara K, Berkower, Ira
Published in PloS one (04.03.2020)
Published in PloS one (04.03.2020)
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The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells
Gupta, Sandeep, Gach, Johannes S, Becerra, Juan C, Phan, Tran B, Pudney, Jeffrey, Moldoveanu, Zina, Joseph, Sarah B, Landucci, Gary, Supnet, Medalyn Jude, Ping, Li-Hua, Corti, Davide, Moldt, Brian, Hel, Zdenek, Lanzavecchia, Antonio, Ruprecht, Ruth M, Burton, Dennis R, Mestecky, Jiri, Anderson, Deborah J, Forthal, Donald N
Published in PLoS pathogens (01.11.2013)
Published in PLoS pathogens (01.11.2013)
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Localization of infection in neonatal rhesus macaques after oral viral challenge
Taylor, Roslyn A, McRaven, Michael D, Carias, Ann M, Anderson, Meegan R, Matias, Edgar, Araínga, Mariluz, Allen, Edward J, Rogers, Kenneth A, Gupta, Sandeep, Kulkarni, Viraj, Lakhashe, Samir, Lorenzo-Redondo, Ramon, Thomas, Yanique, Strickland, Amanda, Villinger, Francois J, Ruprecht, Ruth M, Hope, Thomas J
Published in PLoS pathogens (01.11.2021)
Published in PLoS pathogens (01.11.2021)
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Cooperation Between Systemic IgG1 and Mucosal Dimeric IgA2 Monoclonal Anti-HIV Env Antibodies: Passive Immunization Protects Indian Rhesus Macaques Against Mucosal SHIV Challenges
Gong, Siqi, Lakhashe, Samir K, Hariraju, Dinesh, Scinto, Hanna, Lanzavecchia, Antonio, Cameroni, Elisabetta, Corti, Davide, Ratcliffe, Sarah J, Rogers, Kenneth A, Xiao, Peng, Fontenot, Jane, Villinger, François, Ruprecht, Ruth M
Published in Frontiers in immunology (03.08.2021)
Published in Frontiers in immunology (03.08.2021)
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ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type
Schifanella, Luca, Barnett, Susan W, Bissa, Massimiliano, Galli, Veronica, Doster, Melvin N, Vaccari, Monica, Tomaras, Georgia D, Shen, Xiaoying, Phogat, Sanjay, Pal, Ranajit, Montefiori, David C, LaBranche, Celia C, Rao, Mangala, Trinh, Hung V, Washington-Parks, Robyn, Liyanage, Namal P M, Gorini, Giacomo, Brown, Dallas R, Liang, Frank, Loré, Karin, Venzon, David J, Magnanelli, William, Metrinko, Michelle, Kramer, Josh, Breed, Matthew, Alter, Galit, Ruprecht, Ruth M, Franchini, Genoveffa
Published in PLoS pathogens (01.12.2019)
Published in PLoS pathogens (01.12.2019)
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Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges
Lakhashe, Samir K, Amacker, Mario, Hariraju, Dinesh, Vyas, Hemant K, Morrison, Kyle S, Weiner, Joshua A, Ackerman, Margaret E, Roy, Vicky, Alter, Galit, Ferrari, Guido, Montefiori, David C, Tomaras, Georgia D, Sawant, Sheetal, Yates, Nicole L, Gast, Chris, Fleury, Sylvain, Ruprecht, Ruth M
Published in Frontiers in immunology (22.02.2022)
Published in Frontiers in immunology (22.02.2022)
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Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type
Schifanella, Luca, Barnett, Susan W, Bissa, Massimiliano, Galli, Veronica, Doster, Melvin N, Vaccari, Monica, Tomaras, Georgia D, Shen, Xiaoying, Phogat, Sanjay, Pal, Ranajit, Montefiori, David C, LaBranche, Celia C, Rao, Mangala, Trinh, Hung V, Washington-Parks, Robyn, Liyanage, Namal P M, Gorini, Giacomo, Brown, Dallas R, Liang, Frank, Loré, Karin, Venzon, David J, Magnanelli, William, Metrinko, Michelle, Kramer, Josh, Breed, Matthew, Alter, Galit, Ruprecht, Ruth M, Franchini, Genoveffa
Published in PLoS pathogens (28.04.2020)
Published in PLoS pathogens (28.04.2020)
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Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells?
Gong, Siqi, Gautam, Seijal, Coneglio, Joshua D, Scinto, Hanna B, Ruprecht, Ruth M
Published in Antibodies (Basel) (18.05.2022)
Published in Antibodies (Basel) (18.05.2022)
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An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV
Watkins, Jennifer D, Siddappa, Nagadenahalli B, Lakhashe, Samir K, Humbert, Michael, Sholukh, Anton, Hemashettar, Girish, Wong, Yin Ling, Yoon, John K, Wang, Wendy, Novembre, Francis J, Villinger, Francois, Ibegbu, Chris, Patel, Kalpana, Corti, Davide, Agatic, Gloria, Vanzetta, Fabrizia, Bianchi, Siro, Heeney, Jonathan L, Sallusto, Federica, Lanzavecchia, Antonio, Ruprecht, Ruth M
Published in PloS one (31.03.2011)
Published in PloS one (31.03.2011)
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Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge
Malherbe, Delphine C, Vang, Lo, Mendy, Jason, Barnette, Philip T, Spencer, David A, Reed, Jason, Kareko, Bettie W, Sather, D Noah, Pandey, Shilpi, Wibmer, Constantinos K, Robins, Harlan, Fuller, Deborah H, Park, Byung, Lakhashe, Samir K, Wilson, James M, Axthelm, Michael K, Ruprecht, Ruth M, Moore, Penny L, Sacha, Jonah B, Hessell, Ann J, Alexander, Jeff, Haigwood, Nancy L
Published in Frontiers in immunology (15.02.2021)
Published in Frontiers in immunology (15.02.2021)
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Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
Ruprecht, Ruth M, Baba, Timothy W, Liska, Vladimir, Hofmann-Lehmann, Regina, Vlasak, Josef, Xu, Weidong, Ayehunie, Seyoum, Cavacini, Lisa A, Posner, Marshall R, Katinger, Hermann, Stiegler, Gabriela, Bernacky, Bruce J, Rizvi, Tahir A, Schmidt, Russell, Hill, Lori R, Keeling, Michale E, Lu, Yichen, Wright, Joel E, Chou, Ting-Chao
Published in Nature medicine (01.02.2000)
Published in Nature medicine (01.02.2000)
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Relative Transmissibility of an R5 Clade C Simian- Human Immunodeficiency Virus Across Different Mucosae in Macaques Parallels the Relative Risks of Sexual HIV-1 Transmission in Humans via Different Routes
Chenine, Agnès L., Siddappa, Nagadenahalli B., Kramer, Victor G., Sciaranghella, Gaia, Rasmussen, Robert A., Lee, Sandra J., Santosuosso, Michael, Poznansky, Mark C., Velu, Vijayakumar, Amara, Rama R., Souder, Chris, Anderson, Daniel C., Villinger, François, Else, James G., Novembre, Francis J., Strobert, Elizabeth, O'Neil, Shawn P., Secor, W. Evan, Ruprecht, Ruth M.
Published in The Journal of infectious diseases (15.04.2010)
Published in The Journal of infectious diseases (15.04.2010)
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R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models
Siddappa, Nagadenahalli B, Watkins, Jennifer D, Wassermann, Klemens J, Song, Ruijiang, Wang, Wendy, Kramer, Victor G, Lakhashe, Samir, Santosuosso, Michael, Poznansky, Mark C, Novembre, Francis J, Villinger, François, Else, James G, Montefiori, David C, Rasmussen, Robert A, Ruprecht, Ruth M
Published in PloS one (21.07.2010)
Published in PloS one (21.07.2010)
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Efficiency of Neutralizing Antibodies Targeting the CD4-Binding Site: Influence of Conformational Masking by the V2 Loop in R5-Tropic Clade C Simian-Human Immunodeficiency Virus
Watkins, Jennifer D., Diaz-Rodriguez, Juan, Siddappa, Nagadenahalli B., Corti, Davide, Ruprecht, Ruth M.
Published in Journal of Virology (01.12.2011)
Published in Journal of Virology (01.12.2011)
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Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41
Zhang, Mei-Yun, Yuan, Tingting, Li, Jingjing, Rosa Borges, Andrew, Watkins, Jennifer D, Guenaga, Javier, Yang, Zheng, Wang, Yanping, Wilson, Richard, Li, Yuxing, Polonis, Victoria R, Pincus, Seth H, Ruprecht, Ruth M, Dimitrov, Dimiter S
Published in PloS one (10.09.2012)
Published in PloS one (10.09.2012)
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