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Chaykovska, Lyubov, von Websky, Karoline, Rahnenführer, Jan, Alter, Markus, Heiden, Susi, Fuchs, Holger, Runge, Frank, Klein, Thomas, Hocher, Berthold
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Published in PloS one (18.11.2011)
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The Novel Phosphodiesterase 9A Inhibitor BI 409306 Increases Cyclic Guanosine Monophosphate Levels in the Brain, Promotes Synaptic Plasticity, and Enhances Memory Function in Rodents
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A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory Guidance
Schadt, Simone, Bister, Bojan, Chowdhury, Swapan K, Funk, Christoph, Hop, Cornelis E C A, Humphreys, W Griffith, Igarashi, Fumihiko, James, Alexander D, Kagan, Mark, Khojasteh, S Cyrus, Nedderman, Angus N R, Prakash, Chandra, Runge, Frank, Scheible, Holger, Spracklin, Douglas K, Swart, Piet, Tse, Susanna, Yuan, Josh, Obach, R Scott
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Relative bioavailability of an empagliflozin 25-mg/linagliptin 5-mg fixed-dose combination tablet
Glund, Stephan, Mattheus, Michaela, Runge, Frank, Rose, Peter, Friedrich, Christian
Published in International journal of clinical pharmacology and therapeutics (01.04.2017)
Published in International journal of clinical pharmacology and therapeutics (01.04.2017)
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A phase I, randomized, proof‐of‐clinical‐mechanism study assessing the pharmacokinetics and pharmacodynamics of the oral PDE9A inhibitor BI 409306 in healthy male volunteers
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Published in Human psychopharmacology (01.01.2017)
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Range of Neurological Signs in Cynomolgus Monkeys After Intrathecal Bolus Administration of Antisense Oligonucleotides
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Published in International journal of toxicology (01.11.2020)
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Published in International journal of toxicology (01.11.2020)
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Acoustic Ejection Mass Spectrometry: A Fully Automatable Technology for High-Throughput Screening in Drug Discovery
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Published in SLAS discovery (01.09.2021)
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Year of Publication 06.12.2022
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Year of Publication 06.12.2022
Patent
Improving synaptic plasticity and cognitive function in rodents by the novel phosphodiesterase 9A inhibitor bi 409306
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Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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P2‐310: Improving synaptic plasticity and cognitive function in rodents by the novel phosphodiesterase 9A inhibitor bi 409306
Rosenbrock, Holger, Marti, Anelise, Koros, Eliza, Runge, Frank, Fuchs, Holger, Giovannini, Riccardo, Dorner-Ciossek, Cornelia
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein–Ligand Interactions at High Throughput
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Published in SLAS discovery (01.01.2021)
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