A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy
Klopstock, Thomas, Yu-Wai-Man, Patrick, Dimitriadis, Konstantinos, Rouleau, Jacinthe, Heck, Suzette, Bailie, Maura, Atawan, Alaa, Chattopadhyay, Sandip, Schubert, Marion, Garip, Aylin, Kernt, Marcus, Petraki, Diana, Rummey, Christian, Leinonen, Mika, Metz, Günther, Griffiths, Philip G., Meier, Thomas, Chinnery, Patrick F.
Published in Brain (London, England : 1878) (01.09.2011)
Published in Brain (London, England : 1878) (01.09.2011)
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Journal Article
Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial
Buyse, Gunnar M, Prof, Voit, Thomas, Prof, Schara, Ulrike, Prof, Straathof, Chiara S M, MD, D'Angelo, M Grazia, MD, Bernert, Günther, MD, Cuisset, Jean-Marie, MD, Finkel, Richard S, Prof, Goemans, Nathalie, MD, McDonald, Craig M, Prof, Rummey, Christian, PhD, Meier, Thomas, PhD
Published in The Lancet (British edition) (02.05.2015)
Published in The Lancet (British edition) (02.05.2015)
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Journal Article
Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I
Erb, Michael, Hoffmann-Enger, Barbara, Deppe, Holger, Soeberdt, Michael, Haefeli, Roman H, Rummey, Christian, Feurer, Achim, Gueven, Nuri
Published in PloS one (27.04.2012)
Published in PloS one (27.04.2012)
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Journal Article
Phenotypic variation of FXN compound heterozygotes in a Friedreich ataxia cohort
Shen, Megan M., Rummey, Christian, Lynch, David R.
Published in Annals of clinical and translational neurology (01.05.2024)
Published in Annals of clinical and translational neurology (01.05.2024)
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Journal Article
Idebenone in Friedreich ataxia cardiomyopathy—results from a 6-month phase III study (IONIA)
Lagedrost, Sarah J., BA, Sutton, Martin St. John, MBBS, Cohen, Meryl S., MD, Satou, Gary M., MD, Kaufman, Beth D., MD, Perlman, Susan L., MD, Rummey, Christian, PhD, Meier, Thomas, PhD, Lynch, David R., MD, PhD
Published in The American heart journal (01.03.2011)
Published in The American heart journal (01.03.2011)
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Journal Article
Propensity matched comparison of omaveloxolone treatment to Friedreich ataxia natural history data
Lynch, David R., Goldsberry, Angie, Rummey, Christian, Farmer, Jennifer, Boesch, Sylvia, Delatycki, Martin B., Giunti, Paola, Hoyle, J. Chad, Mariotti, Caterina, Mathews, Katherine D., Nachbauer, Wolfgang, Perlman, Susan, Subramony, S.H., Wilmot, George, Zesiewicz, Theresa, Weissfeld, Lisa, Meyer, Colin
Published in Annals of clinical and translational neurology (01.01.2024)
Published in Annals of clinical and translational neurology (01.01.2024)
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Journal Article
Retinal hypoplasia and degeneration result in vision loss in Friedreich ataxia
Rodden, Layne N., McIntyre, Kellie, Keita, Medina, Wells, Mckenzie, Park, Courtney, Profeta, Victoria, Waldman, Amy, Rummey, Christian, Balcer, Laura J., Lynch, David R.
Published in Annals of clinical and translational neurology (01.08.2023)
Published in Annals of clinical and translational neurology (01.08.2023)
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Journal Article
Digital endpoints for self‐administered home‐based functional assessment in pediatric Friedreich’s ataxia
Mueller, Arne, Paterson, Elaine, McIntosh, Avery, Praestgaard, Jens, Bylo, Mary, Hoefling, Holger, Wells, McKenzie, Lynch, David R., Rummey, Christian, Krishnan, Michelle L., Schultz, Meredith, Malanga, C. J.
Published in Annals of clinical and translational neurology (01.09.2021)
Published in Annals of clinical and translational neurology (01.09.2021)
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Journal Article
Scoliosis in Friedreich's ataxia: longitudinal characterization in a large heterogeneous cohort
Rummey, Christian, Flynn, John M., Corben, Louise A., Delatycki, Martin B., Wilmot, George, Subramony, Sub H., Bushara, Khalaf, Duquette, Antoine, Gomez, Christopher M., Hoyle, J. Chad, Roxburgh, Richard, Seeberger, Lauren, Yoon, Grace, Mathews, Katherine D., Zesiewicz, Theresa, Perlman, Susan, Lynch, David R.
Published in Annals of clinical and translational neurology (01.06.2021)
Published in Annals of clinical and translational neurology (01.06.2021)
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Journal Article
A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia
Rodden, Layne N., Rummey, Christian, Dong, Yi Na, Lagedrost, Sarah, Regner, Sean, Brocht, Alicia, Bushara, Khalaf, Delatycki, Martin B., Gomez, Christopher M., Mathews, Katherine, Murray, Sarah, Perlman, Susan, Ravina, Bernard, Subramony, S. H., Wilmot, George, Zesiewicz, Theresa, Bolotta, Alessandra, Domissy, Alain, Jespersen, Christine, Ji, Baohu, Soragni, Elisabetta, Gottesfeld, Joel M., Lynch, David R.
Published in Frontiers in molecular biosciences (05.09.2022)
Published in Frontiers in molecular biosciences (05.09.2022)
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Journal Article
Peroxomolybdenum Complexes as Epoxidation Catalysts in Biphasic Hydrogen Peroxide Activation: Raman Spectroscopic Studies and Density Functional Calculations
Wahl, Günter, Kleinhenz, Dirk, Schorm, Andrea, Sundermeyer, Jörg, Stowasser, Ralf, Rummey, Christian, Bringmann, Gerhard, Fickert, Claudia, Kiefer, Wolfgang
Published in Chemistry : a European journal (05.11.1999)
Published in Chemistry : a European journal (05.11.1999)
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Journal Article
A Novel Metric for Predicting Severity of Disease Features in Friedreich's Ataxia
Rodden, Layne N., Rummey, Christian, Kessler, Sudha, Wilson, Robert B., Lynch, David R.
Published in Movement disorders (01.06.2023)
Published in Movement disorders (01.06.2023)
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Journal Article
Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Stenosis: A Multicenter Randomized Phase II Trial
Uphaus, Timo, Richards, Toby, Weimar, Christian, Neugebauer, Hermann, Poli, Sven, Weissenborn, Karin, Imray, Christopher, Michalski, Dominik, Rashid, Hisham, Loftus, Ian, Rummey, Christian, Ritter, Martin, Hauser, Till-Karsten, Münch, Götz, Gröschel, Klaus, Poppert, Holger
Published in Stroke (1970) (01.09.2022)
Published in Stroke (1970) (01.09.2022)
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Journal Article
Natural History of Friedreich Ataxia: Heterogeneity of Neurologic Progression and Consequences for Clinical Trial Design
Rummey, Christian, Corben, Louise A, Delatycki, Martin, Wilmot, George, Subramony, Sub H, Corti, Manuela, Bushara, Khalaf, Duquette, Antoine, Gomez, Christopher, Hoyle, J Chad, Roxburgh, Richard, Seeberger, Lauren, Yoon, Grace, Mathews, Katherine, Zesiewicz, Theresa, Perlman, Susan, Lynch, David R
Published in Neurology (04.10.2022)
Published in Neurology (04.10.2022)
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Journal Article
Friedreich’s Ataxia related Diabetes: Epidemiology and management practices
Tamaroff, Jaclyn, DeDio, Anna, Wade, Kristin, Wells, McKenzie, Park, Courtney, Leavens, Karla, Rummey, Christian, Kelly, Andrea, Lynch, David R., McCormack, Shana E.
Published in Diabetes research and clinical practice (01.04.2022)
Published in Diabetes research and clinical practice (01.04.2022)
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Journal Article
Progression characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS): a 4-year cohort study
Reetz, Kathrin, Dogan, Imis, Hilgers, Ralf-Dieter, Giunti, Paola, Parkinson, Michael H, Mariotti, Caterina, Nanetti, Lorenzo, Durr, Alexandra, Ewenczyk, Claire, Boesch, Sylvia, Nachbauer, Wolfgang, Klopstock, Thomas, Stendel, Claudia, Rodríguez de Rivera Garrido, Francisco Javier, Rummey, Christian, Schöls, Ludger, Hayer, Stefanie N, Klockgether, Thomas, Giordano, Ilaria, Didszun, Claire, Rai, Myriam, Pandolfo, Massimo, Schulz, Jörg B, Labrum, Robyn, Thomas-Black, Gilbert, Manso, Katarina, Solanky, Nita, Gellera, Cinzia, Mongelli, Alessia, Castaldo, Anna, Fichera, Mario, Palau, Francesc, O'Callaghan, Mar, Biet, Marie, Monin, Marie Lorraine, Eigentler, Andreas, Indelicato, Elisabetta, Amprosi, Matthias, Radelfahr, Florentine, Bischoff, Almut T., Holtbernd, Florian, Brcina, Nikolina, Hohenfeld, Christian, Koutsis, Georgios, Breza, Marianthi, Bertini, Enrico, Vasco, Gessica
Published in Lancet neurology (01.05.2021)
Published in Lancet neurology (01.05.2021)
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