Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma
Zhang, Qianfei, Ma, Chi, Duan, Yi, Heinrich, Bernd, Rosato, Umberto, Diggs, Laurence P, Ma, Lichun, Roy, Soumen, Fu, Qiong, Brown, Zachary J, Wabitsch, Simon, Thovarai, Vishal, Fu, Jianyang, Feng, Dechun, Ruf, Benjamin, Cui, Linda L, Subramanyam, Varun, Frank, Karen M, Wang, Sophie, Kleiner, David E, Ritz, Thomas, Rupp, Christian, Gao, Bin, Longerich, Thomas, Kroemer, Alexander, Wang, Xin Wei, Ruchirawat, Mathuros, Korangy, Firouzeh, Schnabl, Bernd, Trinchieri, Giorgio, Greten, Tim F
Published in Cancer discovery (01.05.2021)
Published in Cancer discovery (01.05.2021)
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Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD
Ma, Chi, Fu, Qiong, Diggs, Laurence P., McVey, John C., McCallen, Justin, Wabitsch, Simon, Ruf, Benjamin, Brown, Zachary, Heinrich, Bernd, Zhang, Qianfei, Rosato, Umberto, Wang, Sophie, Cui, Linda, Berzofsky, Jay A., Kleiner, David E., Bosco, Dale B., Wu, Long-Jun, Lai, Chunwei Walter, Rotman, Yaron, Xie, Changqing, Korangy, Firouzeh, Greten, Tim F.
Published in Cancer cell (12.09.2022)
Published in Cancer cell (12.09.2022)
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Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma
Heinrich, Bernd, Ruf, Benjamin, Subramanyam, Varun, Myojin, Yuta, Lai, Chunwei W., Craig, Amanda J., Fu, Jianyang, Xie, Changqing, Kroemer, Alexander, Greten, Tim F., Korangy, Firouzeh
Published in Frontiers in immunology (27.06.2022)
Published in Frontiers in immunology (27.06.2022)
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A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells
Buchfellner, Andrea, Yurlova, Larisa, Nüske, Stefan, Scholz, Armin M, Bogner, Jacqueline, Ruf, Benjamin, Zolghadr, Kourosh, Drexler, Sophie E, Drexler, Guido A, Girst, Stefanie, Greubel, Christoph, Reindl, Judith, Siebenwirth, Christian, Romer, Tina, Friedl, Anna A, Rothbauer, Ulrich
Published in PloS one (07.03.2016)
Published in PloS one (07.03.2016)
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Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer
Monge, Cecilia, Xie, Changqing, Myojin, Yuta, Coffman, Kelley, Hrones, Donna Mabry, Wang, Sophie, Hernandez, Jonathan M, Wood, Bradford J, Levy, Elliot B, Juburi, Israa, Hewitt, Stephen M, Kleiner, David E, Steinberg, Seth M, Figg, William D, Redd, Bernadette, Homan, Philip, Cam, Maggie, Ruf, Benjamin, Duffy, Austin G, Greten, Tim F
Published in Journal for immunotherapy of cancer (01.02.2023)
Published in Journal for immunotherapy of cancer (01.02.2023)
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Adenosine A2a receptor inhibition increases the anti-tumor efficacy of anti-PD1 treatment in murine hepatobiliary cancers
Myojin, Yuta, McCallen, Justin D., Ma, Chi, Bauer, Kylynda C., Ruf, Benjamin, Benmebarek, Mohamed-Reda, Green, Benjamin L., Wabitsch, Simon, McVey, John C., Fu, Claude, Xie, Changqing, Greten, Tim F.
Published in JHEP reports (01.01.2024)
Published in JHEP reports (01.01.2024)
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NAFLD indirectly impairs antigen-specific CD8+ T cell immunity against liver cancer in mice
McVey, John C., Green, Benjamin L., Ruf, Benjamin, McCallen, Justin D., Wabitsch, Simon, Subramanyam, Varun, Diggs, Laurence P., Heinrich, Bernd, Greten, Tim F., Ma, Chi
Published in iScience (18.02.2022)
Published in iScience (18.02.2022)
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472 Anti-VEGF treatment amplifies immune checkpoint inhibitor induced immune responses by targeting B and regulatory T cells
Benmebarek, Mohamed-Reda, Oguz, Cihan, Ruf, Benjamin, Myojin, Yuta, Huang, Patrick, Ma, Chi, Bauer, Kylynda, Paya, Marina Villamor, Seifert, Matthias, Lack, Justin, Korangy, Firouzeh, Telford, William, Greten, Tim F
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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988 Vagal-CD8+ T cell neuroimmune axis modulates liver cancer
Bauer, Kylynda C, Ruf, Benjamin, Myojin, Yuta, Benmebarek, Mohamed-Reda, Ma, Chi, Nur, Amran, Qi, Jonathan, Green, Benjamin L, Wabitsch, Simon, Trehan, Rajiv, Springer, Danielle, Noguchi, Audrey, Peiravi, Morteza, Potts, Heather, Korangy, Firouzeh, Greten, Tim F
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Hydroxychloroquine can impair tumor response to anti-PD1 in subcutaneous mouse models
Wabitsch, Simon, McVey, John C., Ma, Chi, Ruf, Benjamin, Kamenyeva, Olena, McCallen, Justin D., Diggs, Laurence P., Heinrich, Bernd, Greten, Tim F.
Published in iScience (22.01.2021)
Published in iScience (22.01.2021)
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Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma
Ruf, Benjamin, Berchtold, Susanne, Venturelli, Sascha, Burkard, Markus, Smirnow, Irina, Prenzel, Tanja, Henning, Stefan W, Lauer, Ulrich M
Published in Molecular therapy. Oncolytics (2015)
Published in Molecular therapy. Oncolytics (2015)
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Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells
Ruf, Benjamin, Heinrich, Bernd, Greten, Tim F.
Published in Cellular & molecular immunology (01.01.2021)
Published in Cellular & molecular immunology (01.01.2021)
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Biomarkers for immunotherapy of hepatocellular carcinoma
Greten, Tim F., Villanueva, Augusto, Korangy, Firouzeh, Ruf, Benjamin, Yarchoan, Mark, Ma, Lichun, Ruppin, Eytan, Wang, Xin W.
Published in Nature reviews. Clinical oncology (01.11.2023)
Published in Nature reviews. Clinical oncology (01.11.2023)
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Innate-like T cells in liver disease
Yang, Albert Ying-Po, Wistuba-Hamprecht, Kilian, Greten, Tim F., Ruf, Benjamin
Published in Trends in immunology (01.07.2024)
Published in Trends in immunology (01.07.2024)
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CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma
Diggs, Laurence P., Ruf, Benjamin, Ma, Chi, Heinrich, Bernd, Cui, Linda, Zhang, Qianfei, McVey, John C., Wabitsch, Simon, Heinrich, Sophia, Rosato, Umberto, Lai, Walter, Subramanyam, Varun, Longerich, Thomas, Loosen, Sven H., Luedde, Tom, Neumann, Ulf Peter, Desar, Sabina, Kleiner, David, Gores, Gregory, Wang, Xin Wei, Greten, Tim F.
Published in Journal of hepatology (01.05.2021)
Published in Journal of hepatology (01.05.2021)
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Metformin treatment rescues CD8+ T-cell response to immune checkpoint inhibitor therapy in mice with NAFLD
Wabitsch, Simon, McCallen, Justin D., Kamenyeva, Olena, Ruf, Benjamin, McVey, John C., Kabat, Juraj, Walz, Juliane S., Rotman, Yaron, Bauer, Kylynda C., Craig, Amanda J., Pouzolles, Marie, Phadke, Ira, Catania, Vanessa, Green, Benjamin L., Fu, Claude, Diggs, Laurence P., Heinrich, Bernd, Wang, Xin Wei, Ma, Chi, Greten, Tim F.
Published in Journal of hepatology (01.09.2022)
Published in Journal of hepatology (01.09.2022)
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Steatohepatitis Impairs T-cell–Directed Immunotherapies Against Liver Tumors in Mice
Heinrich, Bernd, Brown, Zachary J., Diggs, Laurence P., Vormehr, Mathias, Ma, Chi, Subramanyam, Varun, Rosato, Umberto, Ruf, Benjamin, Walz, Juliane S., McVey, John C., Wabitsch, Simon, Fu, Qiong, Yu, Su Jong, Zhang, Qianfei, Lai, Chunwei W., Sahin, Ugur, Greten, Tim F.
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
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The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma
Heinrich, Bernd, Gertz, E Michael, Schäffer, Alejandro A, Craig, Amanda, Ruf, Benjamin, Subramanyam, Varun, McVey, John C, Diggs, Laurence P, Heinrich, Sophia, Rosato, Umberto, Ma, Chi, Yan, Chunhua, Hu, Ying, Zhao, Yongmei, Shen, Tsai-Wei, Kapoor, Veena, Telford, William, Kleiner, David E, Stovroff, Merril K, Dhani, Harmeet S, Kang, Jiman, Fishbein, Thomas, Wang, Xin Wei, Ruppin, E, Kroemer, Alexander, Greten, Tim F, Korangy, Firouzeh
Published in Gut (01.06.2022)
Published in Gut (01.06.2022)
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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin
Ruf, Benjamin, Bruhns, Matthias, Babaei, Sepideh, Kedei, Noemi, Ma, Lichun, Revsine, Mahler, Benmebarek, Mohamed-Reda, Ma, Chi, Heinrich, Bernd, Subramanyam, Varun, Qi, Jonathan, Wabitsch, Simon, Green, Benjamin L, Bauer, Kylynda C, Myojin, Yuta, Greten, Layla T, McCallen, Justin D, Huang, Patrick, Trehan, Rajiv, Wang, Xin, Nur, Amran, Murphy Soika, Dana Qiang, Pouzolles, Marie, Evans, Christine N, Chari, Raj, Kleiner, David E, Telford, William, Dadkhah, Kimia, Ruchinskas, Allison, Stovroff, Merrill K, Kang, Jiman, Oza, Kesha, Ruchirawat, Mathuros, Kroemer, Alexander, Wang, Xin Wei, Claassen, Manfred, Korangy, Firouzeh, Greten, Tim F
Published in Cell (17.08.2023)
Published in Cell (17.08.2023)
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