Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT7/2 inhibitors leading to the identification of a clinical candidate
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Published in Bioorganic & medicinal chemistry letters (01.01.2021)
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Published in Journal of organic chemistry (13.05.2005)
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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor
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2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists
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Published in Bioorganic & medicinal chemistry letters (15.03.2008)
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치환된 1H-이미다조[4,5-b]피리딘-2(3H)-온 및 GLUN2B 수용체 조절제로서의 이의 용도
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Novel non-peptidic neuropeptide Y Y2 receptor antagonists
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Published in Bioorganic & medicinal chemistry letters (08.03.2004)
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34- DISUBSTITUTED OCTAHYDROPYRROLO[34-c]PYRROLES AS OREXIN RECEPTOR MODULATORS
SAVALL BRAD M, CHAI WENYING, SHAH CHANDRAVADAN R, LETAVIC MICHAEL A, LY KIEV S, PIPPEL DANIEL J, STOCKING EMILY M, SWANSON DEVIN M, RUDOLPH DALE A, STROTHER KATHLEEN C, SOYODE JOHNSON AKINOLA, SHIREMAN BROCK T
Year of Publication 11.12.2017
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Year of Publication 11.12.2017
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34- DISUBSTITUTED OCTAHYDROPYRROLO[34-c]PYRROLES AS OREXIN RECEPTOR MODULATORS
SAVALL BRAD M, CHAI WENYING, SHAH CHANDRAVADAN R, LETAVIC MICHAEL A, LY KIEV S, PIPPEL DANIEL J, STOCKING EMILY M, SWANSON DEVIN M, RUDOLPH DALE A, STROTHER KATHLEEN C, SOYODE JOHNSON AKINOLA, SHIREMAN BROCK T
Year of Publication 08.12.2017
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Year of Publication 08.12.2017
Patent
Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyra- zolo[3,4-d]azepines as 5-HT7/2 inhibitors leading to the identification of a clinical candidate
Dvorak, Curt A., Rudolph, Dale A., Nepomuceno, Diane, Dvorak, Lisa, Lord, Brian, Fraser, Ian, Bonaventure, Pascal, Lovenberg, Timothy, Carruthers, Nicholas I.
Published in Bioorganic & medicinal chemistry letters (01.01.2021)
Published in Bioorganic & medicinal chemistry letters (01.01.2021)
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DISUBSTITUTED OCTAHY - DROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS
SAVALL BRAD M, CHAI WENYING, SHAH CHANDRAVADAN R, LETAVIC MICHAEL A, LY KIEV S, PIPPEL DANIEL J, STOCKING EMILY M, SWANSON DEVIN M, RUDOLPH DALE A, STROTHER KATHLEEN C, SOYODE JOHNSON AKINOLA, SHIREMAN BROCK T
Year of Publication 25.09.2012
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Year of Publication 25.09.2012
Patent
Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT 7/2 inhibitors leading to the identification of a clinical candidate
Dvorak, Curt A, Rudolph, Dale A, Nepomuceno, Diane, Dvorak, Lisa, Lord, Brian, Fraser, Ian, Bonaventure, Pascal, Lovenberg, Timothy, Carruthers, Nicholas I
Published in Bioorganic & medicinal chemistry letters (01.01.2021)
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Published in Bioorganic & medicinal chemistry letters (01.01.2021)
Journal Article
The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y sub(2) receptor
Swanson, Devin M, Wong, Victoria D, Jablonowski, Jill A, Shah, Chandra, Rudolph, Dale A, Dvorak, Curt A, Seierstad, Mark, Dvorak, Lisa K, Morton, Kirsten, Nepomuceno, Diane, Atack, John R, Bonaventure, Pascal, Lovenberg, Timothy W, Carruthers, Nicholas I
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108]
Shireman, Brock T., Dvorak, Curt A., Rudolph, Dale A., Bonaventure, Pascal, Nepomuceno, Diane, Dvorak, Lisa, Miller, Kirsten L., Lovenberg, Timothy W., Carruthers, Nicholas I.
Published in Bioorganic & medicinal chemistry letters (15.07.2008)
Published in Bioorganic & medicinal chemistry letters (15.07.2008)
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Journal Article
2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT 2A antagonists
Shireman, Brock T., Dvorak, Curt A., Rudolph, Dale A., Bonaventure, Pascal, Nepomuceno, Diane, Dvorak, Lisa, Miller, Kirsten L., Lovenberg, Timothy W., Carruthers, Nicholas I.
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
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