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Published in Cancer cell (13.01.2014)
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Preclinical studies of RA475, a guanidine-substituted spirocyclic candidate RPN13/ADRM1 inhibitor for treatment of ovarian cancer
Anchoori, Ravi K, Tseng, Ssu-Hsueh, Tsai, Hua-Ling, Palande, Vikrant, Rudek, Michelle A, Roden, Richard B S
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Published in PloS one (11.07.2024)
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HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy
Salman, Shaima, Meyers, David J, Wicks, Elizabeth E, Lee, Sophia N, Datan, Emmanuel, Thomas, Aline M, Anders, Nicole M, Hwang, Yousang, Lyu, Yajing, Yang, Yongkang, Jackson, 3rd, Walter, Dordai, Dominic, Rudek, Michelle A, Semenza, Gregg L
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Published in The lancet oncology (01.09.2011)
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Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
GOTINK, Kristy J, BROXTERMAN, Henk J, GRIFFIOEN, Arjan W, ASSARAF, Yehuda G, PILI, Roberto, PETERS, Godefridus J, VERHEUL, Henk M. W, LABOTS, Mariette, DE HAAS, Richard R, DEKKER, Henk, HONEYWELL, Richard J, RUDEK, Michelle A, BEEREPOOT, Laurens V, MUSTERS, René J, JANSEN, Gerrit
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Targeting DDX3 with a small molecule inhibitor for lung cancer therapy
Bol, Guus M, Vesuna, Farhad, Xie, Min, Zeng, Jing, Aziz, Khaled, Gandhi, Nishant, Levine, Anne, Irving, Ashley, Korz, Dorian, Tantravedi, Saritha, Heerma van Voss, Marise R, Gabrielson, Kathleen, Bordt, Evan A, Polster, Brian M, Cope, Leslie, van der Groep, Petra, Kondaskar, Atul, Rudek, Michelle A, Hosmane, Ramachandra S, van der Wall, Elsken, van Diest, Paul J, Tran, Phuoc T, Raman, Venu
Published in EMBO molecular medicine (01.05.2015)
Published in EMBO molecular medicine (01.05.2015)
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Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice
Zhang, Jing, Sharma, Deepti, Dinabandhu, Aumreetam, Sanchez, Jaron, Applewhite, Brooks, Jee, Kathleen, Deshpande, Monika, Flores-Bellver, Miguel, Hu, Ming-Wen, Guo, Chuanyu, Salman, Shaima, Hwang, Yousang, Anders, Nicole M, Rudek, Michelle A, Qian, Jiang, Canto-Soler, M Valeria, Semenza, Gregg L, Montaner, Silvia, Sodhi, Akrit
Published in The Journal of clinical investigation (03.07.2023)
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Phase II Trial of Imatinib in AIDS-Associated Kaposi's Sarcoma: AIDS Malignancy Consortium Protocol 042
KOON, Henry B, KROWN, Susan E, NOY, Ariela, LEE, Jeannette Y, HONDA, Kord, RAPISUWON, Suthee, ZHENGHE WANG, ABOULAFIA, David, REID, Erin G, RUDEK, Michelle A, DEZUBE, Bruce J
Published in Journal of clinical oncology (10.02.2014)
Published in Journal of clinical oncology (10.02.2014)
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Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor
Anchoori, Ravi K, Anchoori, Vidyasagar, Lam, Brandon, Tseng, Ssu-Hsueh, Das, Samarjit, Velasquez, Fernanda Carrizo, Karanam, Balasubramanyam, Poddatoori, Deepika, Patnam, Ramesh, Rudek, Michelle A, Chang, Yung-Nien, Roden, Richard B S
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A phase 1 trial of the oral DNA methyltransferase inhibitor CC‐486 and the histone deacetylase inhibitor romidepsin in advanced solid tumors
Gaillard, Stéphanie L., Zahurak, Marianna, Sharma, Anup, Durham, Jennifer N., Reiss, Kim A., Sartorius‐Mergenthaler, Susan, Downs, Melinda, Anders, Nicole M., Ahuja, Nita, Rudek, Michelle A., Azad, Nilofer
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Castration-Dependent Pharmacokinetics of Docetaxel in Patients With Prostate Cancer
FRANKE, Ryan M, CARDUCCI, Michael A, RUDEK, Michelle A, BAKER, Sharyn D, SPARREBOOM, Alex
Published in Journal of clinical oncology (20.10.2010)
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DNA methyltransferase inhibitor exposure–response: Challenges and opportunities
Kagan, Amanda B., Garrison, Dominique A., Anders, Nicole M., Webster, Jonathan A., Baker, Sharyn D., Yegnasubramanian, Srinivasan, Rudek, Michelle A.
Published in Clinical and translational science (01.08.2023)
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Interaction of the Multikinase Inhibitors Sorafenib and Sunitinib with Solute Carriers and ATP-Binding Cassette Transporters
Hu, Shuiying, Chen, Zhaoyuan, Franke, Ryan, Orwick, Shelley, Zhao, Ming, Rudek, Michelle A, Sparreboom, Alex, Baker, Sharyn D
Published in Clinical cancer research (01.10.2009)
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Ezrin Inhibition Up-regulates Stress Response Gene Expression
Çelik, Haydar, Bulut, Gülay, Han, Jenny, Graham, Garrett T., Minas, Tsion Z., Conn, Erin J., Hong, Sung-Hyeok, Pauly, Gary T., Hayran, Mutlu, Li, Xin, Özdemirli, Metin, Ayhan, Ayşe, Rudek, Michelle A., Toretsky, Jeffrey A., Üren, Aykut
Published in The Journal of biological chemistry (17.06.2016)
Published in The Journal of biological chemistry (17.06.2016)
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A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation
Bisht, Savita, Khan, Mehtab A, Bekhit, Mena, Bai, Haibo, Cornish, Toby, Mizuma, Masamichi, Rudek, Michelle A, Zhao, Ming, Maitra, Amarnath, Ray, Balmiki, Lahiri, Debomoy, Maitra, Anirban, Anders, Robert A
Published in Laboratory investigation (01.09.2011)
Published in Laboratory investigation (01.09.2011)
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TKTL1 Is Activated by Promoter Hypomethylation and Contributes to Head and Neck Squamous Cell Carcinoma Carcinogenesis through Increased Aerobic Glycolysis and HIF1α Stabilization
Sun, Wenyue, Liu, Yan, Glazer, Chad A., Shao, Chunbo, Bhan, Sheetal, Demokan, Semra, Zhao, Ming, Rudek, Michelle A., Ha, Patrick K., Califano, Joseph A.
Published in Clinical cancer research (01.02.2010)
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The effect of regadenoson-induced transient disruption of the blood–brain barrier on temozolomide delivery to normal rat brain
Jackson, Sadhana, Anders, Nicole M., Mangraviti, Antonella, Wanjiku, Teresia M., Sankey, Eric W., Liu, Ann, Brem, Henry, Tyler, Betty, Rudek, Michelle A., Grossman, Stuart A.
Published in Journal of neuro-oncology (01.02.2016)
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Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms
GORE, Steven D, BAYLIN, Stephen, RUDEK, Michelle A, MING ZHAO, SMITH, B. Douglas, MANNING, Jasper, JIEMJIT, Anchalee, DOVER, George, MAYS, Abbie, ZWIEBEL, James, MURGO, Anthony, WENG, Li-Jun, SUGAR, Elizabeth, HERMAN, James G, CARRAWAY, Hetty, MILLER, Carole B, CARDUCCI, Michael, GREVER, Michael, GALM, Oliver, DAUSES, Tianna, KARP, Judith E
Published in Cancer research (Chicago, Ill.) (15.06.2006)
Published in Cancer research (Chicago, Ill.) (15.06.2006)
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