Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
Kang, Tae-Won, Yevsa, Tetyana, Woller, Norman, Hoenicke, Lisa, Wuestefeld, Torsten, Dauch, Daniel, Hohmeyer, Anja, Gereke, Marcus, Rudalska, Ramona, Potapova, Anna, Iken, Marcus, Vucur, Mihael, Weiss, Siegfried, Heikenwalder, Mathias, Khan, Sadaf, Gil, Jesus, Bruder, Dunja, Manns, Michael, Schirmacher, Peter, Tacke, Frank, Ott, Michael, Luedde, Tom, Longerich, Thomas, Kubicka, Stefan, Zender, Lars
Published in Nature (London) (24.11.2011)
Published in Nature (London) (24.11.2011)
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Journal Article
A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer
Dauch, Daniel, Rudalska, Ramona, Cossa, Giacomo, Nault, Jean-Charles, Kang, Tae-Won, Wuestefeld, Torsten, Hohmeyer, Anja, Imbeaud, Sandrine, Yevsa, Tetyana, Hoenicke, Lisa, Pantsar, Tatu, Bozko, Przemyslaw, Malek, Nisar P, Longerich, Thomas, Laufer, Stefan, Poso, Antti, Zucman-Rossi, Jessica, Eilers, Martin, Zender, Lars
Published in Nature medicine (01.07.2016)
Published in Nature medicine (01.07.2016)
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Journal Article
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
Rudalska, Ramona, Dauch, Daniel, Longerich, Thomas, McJunkin, Katherine, Wuestefeld, Torsten, Kang, Tae-Won, Hohmeyer, Anja, Pesic, Marina, Leibold, Josef, von Thun, Anne, Schirmacher, Peter, Zuber, Johannes, Weiss, Karl-Heinz, Powers, Scott, Malek, Nisar P, Eilers, Martin, Sipos, Bence, Lowe, Scott W, Geffers, Robert, Laufer, Stefan, Zender, Lars
Published in Nature medicine (01.10.2014)
Published in Nature medicine (01.10.2014)
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Journal Article
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles
Schwarz, Moritz, Kurkunov, Maksym, Wittlinger, Florian, Rudalska, Ramona, Wang, Guiqun, Schwalm, Martin Peter, Rasch, Alexander, Wagner, Benedikt, Laufer, Stefan A., Knapp, Stefan, Dauch, Daniel, Gehringer, Matthias
Published in Journal of medicinal chemistry (25.04.2024)
Published in Journal of medicinal chemistry (25.04.2024)
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Journal Article
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on S N Ar Electrophiles
Schwarz, Moritz, Kurkunov, Maksym, Wittlinger, Florian, Rudalska, Ramona, Wang, Guiqun, Schwalm, Martin Peter, Rasch, Alexander, Wagner, Benedikt, Laufer, Stefan A, Knapp, Stefan, Dauch, Daniel, Gehringer, Matthias
Published in Journal of medicinal chemistry (25.04.2024)
Published in Journal of medicinal chemistry (25.04.2024)
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Journal Article
Deregulated MYC expression induces dependence upon AMPK-related kinase 5
Liu, Lidan, Ulbrich, Jannes, Müller, Judith, Wüstefeld, Torsten, Aeberhard, Lukas, Kress, Theresia R., Muthalagu, Nathiya, Rycak, Lukas, Rudalska, Ramona, Moll, Roland, Kempa, Stefan, Zender, Lars, Eilers, Martin, Murphy, Daniel J.
Published in Nature (London) (29.03.2012)
Published in Nature (London) (29.03.2012)
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Journal Article
A Direct In Vivo RNAi Screen Identifies MKK4 as a Key Regulator of Liver Regeneration
Wuestefeld, Torsten, Pesic, Marina, Rudalska, Ramona, Dauch, Daniel, Longerich, Thomas, Kang, Tae-Won, Yevsa, Tetyana, Heinzmann, Florian, Hoenicke, Lisa, Hohmeyer, Anja, Potapova, Anna, Rittelmeier, Ina, Jarek, Michael, Geffers, Robert, Scharfe, Maren, Klawonn, Frank, Schirmacher, Peter, Malek, Nisar P., Ott, Michael, Nordheim, Alfred, Vogel, Arndt, Manns, Michael P., Zender, Lars
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
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Journal Article
Abstract 4377: Liver X receptor mediated lipotoxicity represents a treatment option for liver cancer
Rudalska, Ramona, Harbig, Jule, Snaebjoernsson, Marteinn, Taranets, Lyudmyla, Heinzmann, Florian, Zwirner, Stefan, Hu, Wei Ciu, Kronenberger, Thales, Kang, Tae-Won, Poso, Antti, Laufer, Stefan, Rosenfeldt, Mathias, Malek, Nisar P., Pichler, Bernd, Popov, Nikita, Schulze, Almut, Zender, Lars, Dauch, Daniel
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer
Rudalska, Ramona, Harbig, Jule, Snaebjornsson, Marteinn T, Klotz, Sabrina, Zwirner, Stefan, Taranets, Liudmyla, Heinzmann, Florian, Kronenberger, Thales, Forster, Michael, Cui, Wei, D'Artista, Luana, Einig, Elias, Hinterleitner, Martina, Schmitz, Werner, Dylawerska, Agata, Kang, Tae-Won, Poso, Antti, Rosenfeldt, Mathias T, Malek, Nisar P, Bitzer, Michael, Laufer, Stefan, Pichler, Bernd J, Popov, Nikita, Schulze, Almut, Zender, Lars, Dauch, Daniel
Published in Nature cancer (01.02.2021)
Published in Nature cancer (01.02.2021)
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Journal Article
Abstract 1257: A MYC-Aurka protein complex represents an actionable target in p53 altered liver cancer
Daniel, Dauch, Rudalska, Ramona, Cossa, Giacomo, Nault, Jean Charles, Imbeaud, Sandrine, Malek, Nisar P., Longerich, Thomas, Laufer, Stefan, Poso, Antti, Zucman-Rossi, Jessica, Eilers, Martin, Zender, Lars
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 4876: Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib
Rudalska, Ramona, Dauch, Daniel, McJunkin, Katherine, Kang, Tae-Won, Wuestefeld, Torsten, Geffers, Robert, Lowe, Scott W., Zender, Lars
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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