Tumor mutational burden predicts the efficacy of pembrolizumab monotherapy: a pan-tumor retrospective analysis of participants with advanced solid tumors
Cristescu, Razvan, Aurora-Garg, Deepti, Albright, Andrew, Xu, Lei, Liu, Xiao Qiao, Loboda, Andrey, Lang, Lixin, Jin, Fan, Rubin, Eric H, Snyder, Alexandra, Lunceford, Jared
Published in Journal for immunotherapy of cancer (01.01.2022)
Published in Journal for immunotherapy of cancer (01.01.2022)
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Journal Article
Defining tumor resistance to PD-1 pathway blockade: recommendations from the first meeting of the SITC Immunotherapy Resistance Taskforce
Kluger, Harriet M., Tawbi, Hussein A., Ascierto, Maria L., Bowden, Michaela, Callahan, Margaret K., Cha, Edward, Chen, Helen X., Drake, Charles G., Feltquate, David M., Ferris, Robert L., Gulley, James L., Gupta, Shilpa, Humphrey, Rachel W., LaVallee, Theresa M., Le, Dung T., Hubbard-Lucey, Vanessa M., Papadimitrakopoulou, Vassiliki A., Postow, Michael A., Rubin, Eric H., Sharon, Elad, Taube, Janis M., Topalian, Suzanne L., Zappasodi, Roberta, Sznol, Mario, Sullivan, Ryan J.
Published in Journal for immunotherapy of cancer (01.03.2020)
Published in Journal for immunotherapy of cancer (01.03.2020)
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Journal Article
Rendering the 3 + 3 Design to Rest: More Efficient Approaches to Oncology Dose-Finding Trials in the Era of Targeted Therapy
Nie, Lei, Rubin, Eric H, Mehrotra, Nitin, Pinheiro, José, Fernandes, Laura L, Roy, Amit, Bailey, Stuart, de Alwis, Dinesh P
Published in Clinical cancer research (01.06.2016)
Published in Clinical cancer research (01.06.2016)
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Journal Article
Antitumor activity in RAS-driven tumors by blocking AKT and MEK
Tolcher, Anthony W, Khan, Khurum, Ong, Michael, Banerji, Udai, Papadimitrakopoulou, Vassiliki, Gandara, David R, Patnaik, Amita, Baird, Richard D, Olmos, David, Garrett, Christopher R, Skolnik, Jeffrey M, Rubin, Eric H, Smith, Paul D, Huang, Pearl, Learoyd, Maria, Shannon, Keith A, Morosky, Anne, Tetteh, Ernestina, Jou, Ying-Ming, Papadopoulos, Kyriakos P, Moreno, Victor, Kaiser, Brianne, Yap, Timothy A, Yan, Li, de Bono, Johann S
Published in Clinical cancer research (15.02.2015)
Published in Clinical cancer research (15.02.2015)
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Journal Article
Epothilones: Mechanism of Action and Biologic Activity
GOODIN, Susan, KANE, Michael P, RUBIN, Eric H
Published in Journal of clinical oncology (15.05.2004)
Published in Journal of clinical oncology (15.05.2004)
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Journal Article
Phase I Study of Eribulin Mesylate Administered Once Every 21 Days in Patients with Advanced Solid Tumors
Tan, Antoinette R, Rubin, Eric H, Walton, Diana C, Shuster, Dale E, Wong, Y Nancy, Fang, Fang, Ashworth, Simon, Rosen, Lee S
Published in Clinical cancer research (15.06.2009)
Published in Clinical cancer research (15.06.2009)
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Journal Article
From Famine to Feast: Developing Early-Phase Combination Immunotherapy Trials Wisely
Day, Daphne, Monjazeb, Arta M, Sharon, Elad, Ivy, S Percy, Rubin, Eric H, Rosner, Gary L, Butler, Marcus O
Published in Clinical cancer research (01.09.2017)
Published in Clinical cancer research (01.09.2017)
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Journal Article
Selective Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 Is Generally Well-Tolerated and Has Activity in Non–Small-Cell Lung Cancer and Other Solid Tumors: Results of a Phase I Trial
HERBST, Roy S, MADDOX, Anne-Marie, OCHS, Judith, MUCCI LORUSSO, Patricia, ROTHENBERG, Mace L, SMALL, Eric J, RUBIN, Eric H, BASELGA, Jose, ROJO, Federico, WAUN KI HONG, SWAISLAND, Helen, AVERBUCH, Steven D
Published in Journal of clinical oncology (15.09.2002)
Published in Journal of clinical oncology (15.09.2002)
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Journal Article
Topors Functions as an E3 Ubiquitin Ligase with Specific E2 Enzymes and Ubiquitinates p53
Rajendra, Rajeev, Malegaonkar, Diptee, Pungaliya, Pooja, Marshall, Henderson, Rasheed, Zeshaan, Brownell, James, Liu, Leroy F, Lutzker, Stuart, Saleem, Ahamed, Rubin, Eric H
Published in The Journal of biological chemistry (27.08.2004)
Published in The Journal of biological chemistry (27.08.2004)
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Journal Article
Pharmacokinetic/Pharmacodynamic Modeling and Simulation of Neutropenia during Phase I Development of Liposome-Entrapped Paclitaxel
FETTERLY, Gerald J, GRASELA, Thaddeus H, RUBIN, Eric H, TAN, Antoinette R, SHERMAN, Jeffrey W, DUL, Jeanne L, GRAHN, Amy, LECOMTE, Diane, FIEDLER-KELLY, Jill, DAMJANOV, Nevena, FISHMAN, Mayer, KANE, Michael P
Published in Clinical cancer research (15.09.2008)
Published in Clinical cancer research (15.09.2008)
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Journal Article
Pharmacokinetics of Cetuximab After Administration of Escalating Single Dosing and Weekly Fixed Dosing in Patients with Solid Tumors
TAN, Antoinette R, MOORE, Dirk F, HIDALGO, Manuel, DOROSHOW, James H, POPLIN, Elizabeth A, GOODIN, Susan, MAURO, David, RUBIN, Eric H
Published in Clinical cancer research (01.11.2006)
Published in Clinical cancer research (01.11.2006)
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Journal Article
A Study to Determine the Effects of Food and Multiple Dosing on the Pharmacokinetics of Vorinostat Given Orally to Patients with Advanced Cancer
RUBIN, Eric H, AGRAWAL, Nancy G. B, WAGNER, John A, IWAMOTO, Marian, FRIEDMAN, Evan J, SCOTT, Pamela, MAZINA, Kathryn E, SUN, Linda, LIHONG DU, RICKER, Justin L, FRANKEL, Stanley R, GOTTESDIENER, Keith M
Published in Clinical cancer research (01.12.2006)
Published in Clinical cancer research (01.12.2006)
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Journal Article
A Single Supratherapeutic Dose of Vorinostat Does Not Prolong the QTc Interval in Patients with Advanced Cancer
Munster, Pamela N, Rubin, Eric H, Van Belle, Simon, Friedman, Evan, Patterson, Jaclyn K, Van Dyck, Kristien, Li, Xiadong, Comisar, Wendy, Chodakewitz, Jeffery A, Wagner, John A, Iwamoto, Marian
Published in Clinical cancer research (15.11.2009)
Published in Clinical cancer research (15.11.2009)
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Journal Article
Phase I Dose-Finding Study of Weekly Single-Agent Patupilone in Patients With Advanced Solid Tumors
RUBIN, Eric H, ROTHERMEL, John, TESFAYE, Fisseha, TIANLING CHEN, HUBERT, Martine, HO, Yu-Yun, HSU, Chyi-Hung, OZA, Amit M
Published in Journal of clinical oncology (20.12.2005)
Published in Journal of clinical oncology (20.12.2005)
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Journal Article